|   |
18 | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | N | L | N | H | E | G | A | L | T | L | T | Q | V | V | D | V | P | G | Q | V | Q | P | M | V | V | S | P | D | K | R | Y | L | Y | V | G | V | R | P | E | F | R | V | L | A | Y | R | I | A | P | D | D | G | A | L | T | F | A | A | E | S | A | L | P | G | S | P | T | H | I | S | T | D | H | Q | G | Q | F | V | F |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|
|
|
|   |   |
|   |
|
|   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   | . | . |
|
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |   |
| . |
|
|   |
|   |
|   |   |
|   |
|
|   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | N | P | T | D | L | V | C | C | R | T | L | Q | . |
. |
G | H | S | G | K | V | Y | S | L | D | W | T | P | E | K | N | W | I | . |
V | S | A | S | Q | D | G | R | L | I | V | W | N | A | L | T | S | . |
. |
. |
. |
Q | K | T | H | A | I | K | L | H | C | P | W | V | M | E | C | A | F | A | P | N | G | Q | S | V |
Template Known Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |
| . | . |
|
| S | S |
|  |  |  |  |  |  |
| T | T | S | S |
|  | . |  |  |  |  | T | T | S |  |  |  |  |  |  | T | T | T | T | . | . | . | . |  |  |  |  |  |  |  |
|
|
| T | T |
|
|
|
|  |  |
| T | T | S | S |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  | . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  | . |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
| . | . | . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
51 | . | . | . | . | . | . | . | . | 60 | . | . | . | |
|
. | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | |
. | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | |
|
|
|
. | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . |
  |
  |   |
98 | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | |
|
|
|
. | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
| . | . | . | . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | G | S | Y | N | A | G | N | V | S | V | T | R | L | E | D | G | L | P | V | G | V | V | D | V | V | E | G | L | . |
. |
. |
. |
D | G | C | H | S | A | N | I | S | P | D | N | R | T | L | W | V | P | A | L | K | Q | D | R | I | C | L | F | T | V | S | D | D | G | H | L | V | A | Q | D | P | A | E | V | T | T | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | C | G | G | L | D | S | A | C | S | I | F | N | L | S | S | Q | A | D | R | D | G | N | M | P | V | S | R | V | L | T | G | H | K | G | Y | A | S | S | C | Q | Y | V | P | D | Q | E | T | R | L | I | T | G | S | G | D | Q | T | C | V | L | W | D | V | T | T | G | Q | R | I | S | I | F | G | S | E | F | P | S | G |
Template Known Secondary structure |   |
 |  |
|
| S | S | S |
|
|  |  |  |  |
|
|
|
| S | S |
|
|
| S | S | T | T |
|
| B |
|
|
|
| S | S |
|
|
|
|
| B |
|
| S | S | S | S | S |
|  |  |  |  |
| T | T | S |
|  |  |  |  |
| T | T | T |
|
|  |  |  |  |  |
|
|
| S | S | S | S |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
124 | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . |
  |
  |   |
174 | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
E | G | A | G | P | R | H | M | V | F | H | P | N | E | Q | Y | A | Y | C | V | N | E | L | N | S | S | V | D | V | W | E | L | K | D | P | H | G | N | I | E | C | V | Q | T | L | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
H | T | A | D | V | L | S | L | S | I | N | S | L | N | A | N | M | F | I | S | G | S | C | D | T | T | V | R | L | W | D | L | R | I | T | S | R | A | V | R | T | Y | H | G | H | E | G | D | I | N | S | V | K | F | F | P | D | G | Q | R | F | G | T | G | S | D | D | G | T | C | R | L | F | D | M | R | T | G | H | Q |
Template Known Secondary structure |   |
|
| S |
|  |  |  |  |  |  |
| S | S | S |
|
|  |  |  |  |  |  | T | T | S |
|  |  |  |  |  | T | T | T | T |
|
|
|
|  |  |  |
|
|
| S | S |
|
|
|  |  |  |  |
| T | T | S | S |  |  |  |  |  |
| S | S | S |
|  |  |  |  |  | T | T | T | T |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
204 | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . |
  |
  |   |
|
|
|
|
|
|
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | |
. | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
M | M | P | E | N | F | S | D | T | R | W | A | A | D | I | H | I | T | P | D | G | R | H | L | Y | A | C | D | R | T | A | S | L | I | T | V | F | S | V | S | E | D | G | S | V | L | S | K | E | G | F | Q | P | . |
T | E | T | Q | P | R | G | F | N | V | D | H | S | G | K | Y | L | I | A | A |
Query Conservation |   |
. | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |   |
|   |
|
|
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
| . |   |
|
|
|   |
|
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|
|
|   |   |
|   |
|   |
Template Sequence |   |
L | Q | V | Y | N | R | E | P | D | R | N | D | N | E | L | P | I | V | T | S | V | A | F | S | I | S | G | R | L | L | . |
F | A | G | Y | S | N | G | D | C | Y | V | W | D | T | L | L | A | E | M | V | L | N | L | G | T | L | Q | N | S | H | E | G | R | I | S | C | L | G | L | S | S | D | G | S | A | L | C | T | G |
Template Known Secondary structure |   |
 |  |  |  |
|
|
|
| S | S | S |
|
| S | S |
| S |
| S |  |  |  |  |
| S | S | S | S |  |  | . |  |  |  |
| T | T | S |
|  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |
|
| S |
| S | S |
|
|
|
|
|
|  |  |  |  |
| S | S | S | S |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  | . |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
284 | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | |
. | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . |
  |
  |   |
293 | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | Q | K | S | H | H | I | S | V | Y | E | I | V | G | E |
Query Conservation |   |
  |   |   |   |   |   |
|   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
| . |   |   |
|   |
|
|   |   |
|
|   |
Template Sequence |   |
S | W | D | . |
K | N | L | K | I | W | A | F | S | G | H |
Template Known Secondary structure |   |
| T | T | . | S |
|  |  |  |  |  |
|
| S | S |
Template Predicted Secondary structure |   |
 |
|
| . |
|  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
363 | . | . | |
. | . | . | . | 370 | . | . | . | . | . | . |
  |