|   |
8 | . | 10 | . | . | . | . | . | . | . | . | . | 20 | |
|
|
|
. | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | |
|
|
|
|
|
|
. | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |  | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  | . | . | . | . | . | . | . |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
Query Sequence |   |
A | S | P | E | S | Q | Q | I | H | V | W | N | L | . |
. |
. |
. |
N | H | E | G | A | L | T | L | T | Q | V | V | D | V | P | G | Q | V | Q | P | M | V | V | S | P | D | K | R | Y | L | Y | V | G | V | R | P | E | F | R | V | L | A | Y | R | I | A | P | D | D | G | A | L | T | . |
. |
. |
. |
. |
. |
. |
F | A | A |
Query Conservation |   |
|   |   |   |
|   |   |
|   |
|   |
|   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|
|
|
|   |   |
|   |
|
|   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |
|
|
|
|   |
|   |
|
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | S | D | E | Q | N | H | L | V | V | A | R | V | H | I | P | N | D | V | T | G | K | I | E | C | E | I | K | I | N | H | E | G | E | V | N | R | A | R | Y | X | P | Q | N | P | H | I | I | A | T | K | T | P | S | S | D | V | L | V | F | D | Y | T | K | H | P | A | K | P | D | P | S | G | E | C | N | P | D | L | R |
Template Known Secondary structure |   |
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| S |  |  |  |  |  |  |  |  |  |  | S | S |
|
| S |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |
| S | S | S | S |  |  |  |  |  | G | G | G | S |
| S | S |
|
| T | T |
|
|
|
|
| S |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
71 | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 |
  |
  |   |
77 | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . |
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | S | A | L | P | G | S | P | T | H | I | S | T | D | H | Q | G | Q | F | V | F | V | G | S | Y | N | A | G | N | V | S | V | T | R | L | E | D | G | L | P | . |
. |
. |
. |
. |
V | G | V | V | D | V | V | E | G | L | D | G | C | H | S | A | N | I | S | P | D | N | R | T | L | W | V | P | A | L | K | Q | D | R | I |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | R | G | H | Q | K | E | G | Y | G | L | S | W | N | S | N | L | S | G | H | L | L | S | A | S | D | D | H | T | V | C | L | W | D | I | N | A | G | P | K | E | G | K | I | V | D | A | K | A | I | F | T | G | H | S | A | V | V | E | D | V | A | W | H | L | L | H | E | S | L | F | G | S | V | A | D | D | Q | K | L |
Template Known Secondary structure |   |
 |  |
|
| S | S |
|
|
|
|  |  |  |
| S | S | S | T | T |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  | S | S |
| S |
| S | S |
| S |  |  |  |
| S |  |  |  |
|
|
| S | S |
|  |  |  |  |  |  |
| S | S |
| T | T |  |  |  |  |  |  | T | T | S |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
172 | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . |
  |
  |   |
152 | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
C | L | F | T | V | S | D | D | G | H | L | V | A | Q | D | P | A | E | V | T | T | V | E | G | A | G | P | R | H | M | V | F | H | P | N | E | Q | Y | A | Y | C | V | N | E | L | N | S | S | V | D | V | W | E | L | K | D | P | H | G | N | I | E | C | V | Q | T | L | D | M | M | P | E | N | F | S | D | T | R | W | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
X | I | W | D | T | R | S | N | T | T | S | K | P | S | H | L | V | D | A | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | A | E | V | N | C | L | S | F | N | P | Y | S | E | F | I | L | A | T | G | S | A | D | K | T | V | A | L | W | D | L | R | N | L | K | L | K | L | H | T | F | E | S | H | K | D | E | I |
Template Known Secondary structure |   |
 |  |  |  | S | S | S | S |
| S | S | S |
| S |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | S | S |
|  |  |  |  |  |  |
| S | S |
| S | S |  |  |  |  |  |  | T | T | S |  |  |  |  |  |  | T | T |
| T | T | S |
|
|  |  |  |  |
|
| S | S |
|  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
252 | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . |
  |
  |   |
232 | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | D | I | H | I | T | P | D | G | R | H | L | Y | A | C | D | R | T | A | S | L | I | T | V | F | S | V | S | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | G | S | V | L | S | K | E | G | F | Q | P | T | E | T | Q | P | R | G | F | N | V | D | H | S | G | K | Y | L | I | A | A | G | Q | K | S | H | H | I | S |
Query Conservation |   |
  |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |   |
|   |
|
|   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |
|   |
|   |
|   |
|   |
|
|   |
Template Sequence |   |
F | Q | V | H | W | S | P | H | N | E | T | I | L | A | S | S | G | T | D | R | R | L | N | V | W | D | L | S | K | I | G | E | E | Q | S | A | E | D | A | E | D | G | P | P | E | L | L | F | I | H | G | G | H | T | A | K | I | S | D | F | S | W | N | P | N | E | P | W | V | I | C | S | V | S | E | D | N | I | X | Q |
Template Known Secondary structure |   |
 |  |  |  |  |
| S | S |
| T | T |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  | G | G | G | T | T |
|
|
|
|  |  |  |  | T | T |
|
| T | T |  |  |  |  |  |
|
|
| S | S |
|  |  |  |  |  |  |
| S | S | S | T | T |  |  |  |  |  |  | T | T | S |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . |
  |
  |   |
301 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
Query Sequence |   |
V | Y | E | I | V |
Query Conservation |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
Template Conservation |   |
|
|   |   |
|
Template Sequence |   |
I | W | Q | X | A |
Template Known Secondary structure |   |
 |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
  |   |
400 | . | . | . | . |
  |