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Job DescriptionP52697
Confidence98.81%DateThu Jan 5 12:06:01 GMT 2012
Rank140Aligned Residues285
% Identity10%Templatec2qtbB_
PDB info PDB header:hydrolaseChain: B: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl2 cyclohexylalanine inhibitor
Resolution2.25 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   11........20........ .30.........40.........50.... .....60.........70.........
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Query Sequence  ESQQIHVWNLNHEGALTL. . . TQVVDVPGQVQPMVVSPDKRYLYVGV. . . . . . . . RPEFRVLAYRIAPDDGALTFAAESA
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Template Sequence  QENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKR. . . . QLITEER
Template Known Secondary structure  TTTTT


TTTTTTSSS



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   72.......80.........90.........100.........110.........120.........130.........140 .......
 
   80.........90.........100.........110.........120......... 130.........140...
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Query Sequence  LPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGC. . . . . . . . . . . . . . . . HSANISPDNRTLWV
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Template Sequence  IPNNTQWVTWSPVGHKLAYVW. . NNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAY
Template Known Secondary structure 

SSB

SSTT
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BTTTSB

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   148.150.........160........ .170.........180.........190.........200.........210.........220.....
 
   144.....150.........160.........170.........180.........190.........200.........210.........220...
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Query Sequence  PALKQDRICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPE
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Template Sequence  AQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKF. . . . . . . . . . . . . FVVNTDSLSSVTNATSIQITAPAS
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   226...230.........240.........250.........260........ .270.........280.........290..
 
   224.....230.........240...... ...250.........260.........270.. .......280.........290
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Query Sequence  NFSDTRWAADIHITPDGRHLYAC. . . DRTASLITVFSVSEDGSVLSKEGFQP. . . . . . . . . . TETQPRGFNVDHSGKYLI
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Template Sequence  MLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFY
Template Known Secondary structure  TS
TTSSTTTTTT
GGG

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   293......300.........310.........320.........330.........340.........350.........360.........370..
 
   291 ........300.........310....
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Query Sequence  A. AGQKSHHISVYEIVGEQGLLHEK
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Template Sequence  KIISNEEGYRHICYFQIDKKDCTFI
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   373......380.........390.......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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