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Job DescriptionP52697
Confidence98.79%DateThu Jan 5 12:06:01 GMT 2012
Rank141Aligned Residues309
% Identity9%Templatec2g5tA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2....... 10.........20.........30.........40.........50.........60.........70....
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Query Sequence  KQTVYIAS. . . . . . . PESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTF
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Template Sequence  QFILLEYNYVKQWRHSYTASYDIYDLNKR. . . QLITEERIPNNTQWVTWSPVGHKLAYVW. . NNDIYVKIEPNLPSYRIT
Template Known Secondary structure  S
SSS
TTTT...

SS


SSB

SSSS
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   112.......120.........130.........140 .........150.........160........ .170.........180......
 
   75....80. ........90.........100.........110.........120.
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Query Sequence  AAESALP. . . . . . . . . . . . . . . GSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVD. . . . . . . . . . . . . . . . . .
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Template Sequence  WTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTV
Template Known Secondary structure  S

BTTTSB

TSSSSB

TTSS
TT



STT
SS


BTTS


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   187..190.........200.........210.........220.........230.........240.........250.........260......
 
   122.......130.........140.... .....150.........160.........170..
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . VVEGLDGCHSANISPDNRTLWVP. . . ALKQDRICLFTVSDDGHLVAQDPAEVTT
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Template Conservation   
 
 
                                

 
         
                            
Template Sequence  KFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHI
Template Known Secondary structure  TTS

SSS







TS

SSSSSTTGGGT

TTS
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   267..270.........280.........290.........300.........310.........320.........330.........340......
 
   173......180.........190.........200.........210.........220.........230.........240.........250
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Query Sequence  VEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDGRHLYACDRTA. .
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Template Sequence  EMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMP
Template Known Secondary structure 
SSS
SSSSS




TTSS
TTS
TT
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S

SSS

SSS
GGG
T
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   347..350.........360.........370.........380.........390.........400.........410.........420......
 
   251........260.........270. ........280.........290........ .300.........310.....
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Query Sequence  SLITVFSVSEDGSVLSKEGFQ. . . PTETQPRGFNVDHSGKYLIAAGQKSHH. ISVYEIVGEQGLLHEKG
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Template Conservation      
  
          

         
   
 
 

            
               
 
Template Sequence  GGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLE
Template Known Secondary structure  T
BTT
TT
SSTTT
TTTB
B
TTSS
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TTTT
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   427..430.........440.........450.........460.........470.........480.........490.....
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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