|   |
509 | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | |
. | . | . | . | . | . | 540 | . | |
|
|
. | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | |
|
|
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |  | . | . | . |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
| . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
G | L | A | M | V | I | A | R | N | G | K | A | I | L | Y | D | T | G | L | A | W | P | E | G | D | . |
S | G | Q | Q | L | I | I | P | . |
. |
. |
W | L | H | W | H | N | L | E | P | E | G | V | I | L | S | H | E | H | L | D | H | R | G | G | L | D | S | I | L | H | I | W | P | M | L | W | I | R | S | P | . |
. |
. |
Query Conservation |   |
|
|
|
|
|
|   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |   |   |   |   | . |   |   |   |   |   |
|   |
| . | . | . |   |
|   |   |   |
|
|   |   |
|   |
|
|
|
|
|   |
|   |
|
|   |
|
|   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . | . |
Template Conservation |   |
  |
|   |   |   |
|
|   |   |   |   |   |
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |
|
|
|   |
|
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |
|
|
|   |
|   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . |
|
|
|   |
|   |   |
|
Template Sequence |   |
K | N | T | Y | A | V | Q | F | Q | D | E | I | V | L | I | D | A | G | I | K | F | P | E | D | E | L | L | G | I | D | Y | V | I | P | D | Y | T | Y | L | V | K | N | E | D | K | I | K | G | L | F | I | T | H | G | H | E | D | H | I | G | G | I | P | Y | L | L | R | Q | V | N | I | . |
P | V | Y | G | G | K | L | A |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  | T | T |  |  |  |  |  |
|
|
|
| B |
|
|
| T | T | S | T | T |
| S |  |  |  |  |
|
|  |  |  |  | T | T | G | G | G |  |  |  |  |  |  | S |
|
|
|  |  |  |  | T | T |  |  |  |  |  | T | T |
|
|
| . |
|  |  |  |
|  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
| . |
|  |  |  |
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
22 | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | |
. | . | . | . | . | . | . | 100 |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
582 | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | 640 | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
| . | . | . | . | . | . | . |
|
|  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | N | W | E | H | H | Q | P | C | V | R | G | E | A | W | Q | W | Q | G | L | R | F | S | A | H | W | P | L | Q | G | S | N | D | K | G | N | N | H | S | C | V | V | K | V | D | D | G | T | N | S | I | L | L | T | G | D | . |
. |
. |
. |
. |
. |
. |
I | E | A | P |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|
|
|
|
| . | . | . | . | . | . | . |
|   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |
|
|
| . | . | . | . | . |
|
|
|   |   |   |   |
|   |
|   |   |
|   |
|
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
I | G | L | L | R | N | K | L | E | E | H | G | L | L | R | Q | T | K | L | N | I | I | G | E | D | D | I | V | K | F | R | K | T | A | V | S | F | F | R | T | T | H | S | I | . |
. |
. |
. |
. |
P | D | S | Y | G | I | V | V | K | T | P | P | G | N | I | V | H | T | G | D | F | K | F | D | F | T | P | V | G | E | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | S | T | T | T | T | S |
|  |  |  |
|
| T | T |
|
|  |  |  | T | T |  |  |  |  |  |  |  |
| B |
| S | S | . | . | . | . | . | S | S |
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |
|
| S |
| B |
|
| S | S |
| S | S | S |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
101 | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . |
  |
  |   |
642 | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | |
|
|
|
. | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  | . | . | . | . |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
| . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | E | Q | K | M | L | S | R | Y | W | Q | Q | V | Q | A | T | L | L | Q | . |
. |
. |
. |
V | P | H | H | G | S | N | T | S | S | S | L | P | L | I | Q | R | V | . |
. |
. |
. |
. |
. |
N | G | K | V | A | L | A | S | A | S | R | Y | N | A | W | R | L | P | S | N | K | V | K | H | R | Y | Q | L | Q | G | Y | Q | W |
Query Conservation |   |
  |
|   |   |
|
|   |   |   |   |   |   |
|   |   |
|
|
|
| . | . | . | . |
|   |
|
|
|
|   |
|
|
|
|   |   |
|
|   |   |
| . | . | . | . | . | . |   |
|   |   |
|
|
|
|   |
|   |   |
|
|
|
|
|
|   |   |
|
|
|   |
|
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|   |   |   |   |   |   | . |   |
|
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |
|
|
|
|
|   |   |
|
|
|
|
| . | . |   |
|   |
|   |
|   |   |   |
|   |   |   |
|
|   |
|
Template Sequence |   |
A | N | L | T | K | M | A | E | I | G | K | E | . |
G | V | L | C | L | L | S | D | S | T | N | S | E | N | P | E | F | T | M | S | E | R | R | V | G | E | S | I | H | D | I | F | R | K | V | D | G | R | I | I | F | A | T | F | A | S | N | I | . |
. |
H | R | L | Q | Q | V | I | E | A | A | V | Q | N | G | R | K | V |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  | T | . |
|  |  |  |  |  |  |  |
| T | T | T | T |
|
| S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S |
|  |  |  |  |
|
| T | T |
|  | . | . |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
| . |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
176 | . | . | . | 180 | . | . | . | . | . | . | . | |
. | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | |
|
. | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
  |
  |   |
712 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
Query Sequence |   |
I | D | T | P | H |
Query Conservation |   |
  |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|
Template Sequence |   |
A | V | F | G | R |
Template Known Secondary structure |   |
 |  |  | S |  |
Template Predicted Secondary structure |   |
 |  |  |
|  |
Template SS confidence |   |
|
|
|
|
|
  |   |
253 | . | . | . | . |
  |