Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Q	H	K	L	L	I	N	G	E	L	V	S	G	E	G	E	K	Q	P	V	Y	N	P	A	T	G	D	V	L	L	E	I	A	E	A	S	A	E	Q	V	D	A	A	V	R	A	A	D	A	A	F	A	E	W	G	Q	T	T	P
Secondary structure
SS confidence
Disorder		?	?	?	?	?																																																				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		K	V	R	A	E	C	L	L	K	L	A	D	V	I	E	E	N	G	Q	V	F	A	E	L	E	S	R	N	C	G	K	P	L	H	S	A	F	N	D	E	I	P	A	I	V	D	V	F	R	F	F	A	G	A	A	R	C	L	N	G
Secondary structure
SS confidence
Disorder																																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	A	A	G	E	Y	L	E	G	H	T	S	M	I	R	R	D	P	L	G	V	V	A	S	I	A	P	W	N	Y	P	L	M	M	A	A	W	K	L	A	P	A	L	A	A	G	N	C	V	V	L	K	P	S	E	I	T	P	L	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	L	K	L	A	E	L	A	K	D	I	F	P	A	G	V	I	N	I	L	F	G	R	G	K	T	V	G	D	P	L	T	G	H	P	K	V	R	M	V	S	L	T	G	S	I	A	T	G	E	H	I	I	S	H	T	A	S	S	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		K	R	T	H	M	E	L	G	G	K	A	P	V	I	V	F	D	D	A	D	I	E	A	V	V	E	G	V	R	T	F	G	Y	Y	N	A	G	Q	D	C	T	A	A	C	R	I	Y	A	Q	K	G	I	Y	D	T	L	V	E	K	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	A	A	V	A	T	L	K	S	G	A	P	D	D	E	S	T	E	L	G	P	L	S	S	L	A	H	L	E	R	V	G	K	A	V	E	E	A	K	A	T	G	H	I	K	V	I	T	G	G	E	K	R	K	G	N	G	Y	Y	Y
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		A	P	T	L	L	A	G	A	L	Q	D	D	A	I	V	Q	K	E	V	F	G	P	V	V	S	V	T	P	F	D	N	E	E	Q	V	V	N	W	A	N	D	S	Q	Y	G	L	A	S	S	V	W	T	K	D	V	G	R	A	H	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.
Sequence		V	S	A	R	L	Q	Y	G	C	T	W	V	N	T	H	F	M	L	V	S	E	M	P	H	G	G	Q	K	L	S	G	Y	G	K	D	M	S	L	Y	G	L	E	D	Y	T	V	V	R	H	V	M	V	K	H
Secondary structure
SS confidence
Disorder																																																							?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1wnd chain A Region: 1 - 474 Aligned: 474 Modelled: 474 Confidence: 100.0% Identity: 100% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 3ed6 chain B Region: 1 - 474 Aligned: 473 Modelled: 474 Confidence: 100.0% Identity: 39% PDB header:oxidoreductase Chain: B: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: 1.7 angstrom resolution crystal structure of betaine aldehyde2 dehydrogenase (betb) from staphylococcus aureus Phyre2 PDB 1a4s chain A Region: 2 - 474 Aligned: 470 Modelled: 473 Confidence: 100.0% Identity: 37% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 1bxs chain A Region: 3 - 474 Aligned: 470 Modelled: 472 Confidence: 100.0% Identity: 37% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 2o2q chain A Region: 1 - 474 Aligned: 473 Modelled: 474 Confidence: 100.0% Identity: 35% PDB header:oxidoreductase Chain: A: PDB Molecule:formyltetrahydrofolate dehydrogenase; PDBTitle: crystal structure of the c-terminal domain of rat2 10'formyltetrahydrofolate dehydrogenase in complex with nadp Phyre2 PDB 2ve5 chain H Region: 2 - 474 Aligned: 472 Modelled: 473 Confidence: 100.0% Identity: 39% PDB header:oxidoreductase Chain: H: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: crystallographic structure of betaine aldehyde2 dehydrogenase from pseudomonas aeruginosa Phyre2 PDB 1o9j chain A Region: 2 - 474 Aligned: 471 Modelled: 473 Confidence: 100.0% Identity: 38% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 2jg7 chain G Region: 2 - 474 Aligned: 469 Modelled: 472 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: G: PDB Molecule:antiquitin; PDBTitle: crystal structure of seabream antiquitin and elucidation of2 its substrate specificity Phyre2 PDB 3rh9 chain A Region: 1 - 471 Aligned: 470 Modelled: 471 Confidence: 100.0% Identity: 32% PDB header:oxidoreductase Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase (nad(p)(+)); PDBTitle: the crystal structure of oxidoreductase from marinobacter aquaeolei Phyre2 PDB 1o04 chain A Region: 1 - 474 Aligned: 472 Modelled: 474 Confidence: 100.0% Identity: 38% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 1ag8 chain A Region: 1 - 474 Aligned: 472 Modelled: 474 Confidence: 100.0% Identity: 38% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 2d4e chain B Region: 2 - 474 Aligned: 471 Modelled: 473 Confidence: 100.0% Identity: 36% PDB header:oxidoreductase Chain: B: PDB Molecule:5-carboxymethyl-2-hydroxymuconate semialdehyde PDBTitle: crystal structure of the hpcc from thermus thermophilus hb8 Phyre2 PDB 3ifg chain H Region: 1 - 473 Aligned: 471 Modelled: 473 Confidence: 100.0% Identity: 36% PDB header:oxidoreductase Chain: H: PDB Molecule:succinate-semialdehyde dehydrogenase (nadp+); PDBTitle: crystal structure of succinate-semialdehyde dehydrogenase from2 burkholderia pseudomallei, part 1 of 2 Phyre2 PDB 3iwk chain B Region: 3 - 474 Aligned: 471 Modelled: 472 Confidence: 100.0% Identity: 37% PDB header:oxidoreductase Chain: B: PDB Molecule:aminoaldehyde dehydrogenase; PDBTitle: crystal structure of aminoaldehyde dehydrogenase 1 from2 pisum sativum (psamadh1) Phyre2 PDB 3r31 chain A Region: 2 - 474 Aligned: 471 Modelled: 472 Confidence: 100.0% Identity: 38% PDB header:oxidoreductase Chain: A: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: crystal structure of betaine aldehyde dehydrogenase from agrobacterium2 tumefaciens Phyre2 PDB 3ek1 chain C Region: 1 - 474 Aligned: 470 Modelled: 474 Confidence: 100.0% Identity: 37% PDB header:oxidoreductase Chain: C: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of aldehyde dehydrogenase from brucella2 melitensis biovar abortus 2308 Phyre2 PDB 3k2w chain D Region: 3 - 474 Aligned: 471 Modelled: 472 Confidence: 100.0% Identity: 31% PDB header:oxidoreductase Chain: D: PDB Molecule:betaine-aldehyde dehydrogenase; PDBTitle: crystal structure of betaine-aldehyde dehydrogenase from2 pseudoalteromonas atlantica t6c Phyre2 PDB 3qan chain B Region: 2 - 474 Aligned: 469 Modelled: 473 Confidence: 100.0% Identity: 29% PDB header:oxidoreductase Chain: B: PDB Molecule:1-pyrroline-5-carboxylate dehydrogenase 1; PDBTitle: crystal structure of 1-pyrroline-5-carboxylate dehydrogenase from2 bacillus halodurans Phyre2 PDB 1t90 chain B Region: 2 - 474 Aligned: 471 Modelled: 473 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: B: PDB Molecule:probable methylmalonate-semialdehyde PDBTitle: crystal structure of methylmalonate semialdehyde2 dehydrogenase from bacillus subtilis Phyre2 PDB 3jz4 chain C Region: 1 - 473 Aligned: 471 Modelled: 473 Confidence: 100.0% Identity: 37% PDB header:oxidoreductase Chain: C: PDB Molecule:succinate-semialdehyde dehydrogenase [nadp+]; PDBTitle: crystal structure of e. coli nadp dependent enzyme Phyre2 1 d1wnda_ 2 c3ed6B_ 3 d1a4sa_ 4 d1bxsa_ 5 c2o2qA_ 6 c2ve5H_ 7 d1o9ja_ 8 c2jg7G_ 9 c3rh9A_ 10 d1o04a_ 11 d1ag8a_ 12 c2d4eB_ 13 c3ifgH_ 14 c3iwkB_ 15 c3r31A_ 16 c3ek1C_ 17 c3k2wD_ 18 c3qanB_ 19 c1t90B_ 20 c3jz4C_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1wnda_ 100.0 100 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 2 c3ed6B_ 100.0 39 PDB header:oxidoreductase Chain: B: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: 1.7 angstrom resolution crystal structure of betaine aldehyde2 dehydrogenase (betb) from staphylococcus aureus 3 d1a4sa_ 100.0 37 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 4 d1bxsa_ 100.0 37 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 5 c2o2qA_ 100.0 35 PDB header:oxidoreductase Chain: A: PDB Molecule:formyltetrahydrofolate dehydrogenase; PDBTitle: crystal structure of the c-terminal domain of rat2 10'formyltetrahydrofolate dehydrogenase in complex with nadp 6 c2ve5H_ 100.0 39 PDB header:oxidoreductase Chain: H: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: crystallographic structure of betaine aldehyde2 dehydrogenase from pseudomonas aeruginosa 7 d1o9ja_ 100.0 38 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 8 c2jg7G_ 100.0 28 PDB header:oxidoreductase Chain: G: PDB Molecule:antiquitin; PDBTitle: crystal structure of seabream antiquitin and elucidation of2 its substrate specificity 9 c3rh9A_ 100.0 32 PDB header:oxidoreductase Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase (nad(p)(+)); PDBTitle: the crystal structure of oxidoreductase from marinobacter aquaeolei 10 d1o04a_ 100.0 38 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 11 d1ag8a_ 100.0 38 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 12 c2d4eB_ 100.0 36 PDB header:oxidoreductase Chain: B: PDB Molecule:5-carboxymethyl-2-hydroxymuconate semialdehyde PDBTitle: crystal structure of the hpcc from thermus thermophilus hb8 13 c3ifgH_ 100.0 36 PDB header:oxidoreductase Chain: H: PDB Molecule:succinate-semialdehyde dehydrogenase (nadp+); PDBTitle: crystal structure of succinate-semialdehyde dehydrogenase from2 burkholderia pseudomallei, part 1 of 2 14 c3iwkB_ 100.0 37 PDB header:oxidoreductase Chain: B: PDB Molecule:aminoaldehyde dehydrogenase; PDBTitle: crystal structure of aminoaldehyde dehydrogenase 1 from2 pisum sativum (psamadh1) 15 c3r31A_ 100.0 38 PDB header:oxidoreductase Chain: A: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: crystal structure of betaine aldehyde dehydrogenase from agrobacterium2 tumefaciens 16 c3ek1C_ 100.0 37 PDB header:oxidoreductase Chain: C: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of aldehyde dehydrogenase from brucella2 melitensis biovar abortus 2308 17 c3k2wD_ 100.0 31 PDB header:oxidoreductase Chain: D: PDB Molecule:betaine-aldehyde dehydrogenase; PDBTitle: crystal structure of betaine-aldehyde dehydrogenase from2 pseudoalteromonas atlantica t6c 18 c3qanB_ 100.0 29 PDB header:oxidoreductase Chain: B: PDB Molecule:1-pyrroline-5-carboxylate dehydrogenase 1; PDBTitle: crystal structure of 1-pyrroline-5-carboxylate dehydrogenase from2 bacillus halodurans 19 c1t90B_ 100.0 28 PDB header:oxidoreductase Chain: B: PDB Molecule:probable methylmalonate-semialdehyde PDBTitle: crystal structure of methylmalonate semialdehyde2 dehydrogenase from bacillus subtilis 20 c3jz4C_ 100.0 37 PDB header:oxidoreductase Chain: C: PDB Molecule:succinate-semialdehyde dehydrogenase [nadp+]; PDBTitle: crystal structure of e. coli nadp dependent enzyme 21 c2w8qA_ not modelled 100.0 35 PDB header:oxidoreductase Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase, PDBTitle: the crystal structure of human ssadh in complex with ssa. 22 d1uzba_ not modelled 100.0 29 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 23 c3b4wA_ not modelled 100.0 35 PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of mycobacterium tuberculosis aldehyde dehydrogenase2 complexed with nad+ 24 c3i44A_ not modelled 100.0 31 PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of aldehyde dehydrogenase from bartonella2 henselae at 2.0a resolution 25 d1euha_ not modelled 100.0 30 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 26 c2hg2A_ not modelled 100.0 38 PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase a; PDBTitle: structure of lactaldehyde dehydrogenase 27 c3prlD_ not modelled 100.0 32 PDB header:oxidoreductase Chain: D: PDB Molecule:nadp-dependent glyceraldehyde-3-phosphate dehydrogenase; PDBTitle: crystal structure of nadp-dependent glyceraldehyde-3-phosphate2 dehydrogenase from bacillus halodurans c-125 28 d1ky8a_ not modelled 100.0 29 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 29 c3ju8B_ not modelled 100.0 29 PDB header:oxidoreductase Chain: B: PDB Molecule:succinylglutamic semialdehyde dehydrogenase; PDBTitle: crystal structure of succinylglutamic semialdehyde dehydrogenase from2 pseudomonas aeruginosa. 30 d1bi9a_ not modelled 100.0 36 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 31 c3hazA_ not modelled 100.0 30 PDB header:oxidoreductase Chain: A: PDB Molecule:proline dehydrogenase; PDBTitle: crystal structure of bifunctional proline utilization a2 (puta) protein 32 c3rosA_ not modelled 100.0 29 PDB header:oxidoreductase Chain: A: PDB Molecule:nad-dependent aldehyde dehydrogenase; PDBTitle: crystal structure of nad-dependent aldehyde dehydrogenase from2 lactobacillus acidophilus 33 c2vroB_ not modelled 100.0 22 PDB header:oxidoreductase Chain: B: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of aldehyde dehydrogenase from2 burkholderia xenovorans lb400 34 c3efvC_ not modelled 100.0 30 PDB header:oxidoreductase Chain: C: PDB Molecule:putative succinate-semialdehyde dehydrogenase; PDBTitle: crystal structure of a putative succinate-semialdehyde dehydrogenase2 from salmonella typhimurium lt2 with bound nad 35 c3r64A_ not modelled 100.0 30 PDB header:oxidoreductase Chain: A: PDB Molecule:nad dependent benzaldehyde dehydrogenase; PDBTitle: crystal structure of a nad-dependent benzaldehyde dehydrogenase from2 corynebacterium glutamicum 36 c3pqaA_ not modelled 100.0 31 PDB header:oxidoreductase Chain: A: PDB Molecule:lactaldehyde dehydrogenase; PDBTitle: crystal structure of glyceraldehyde-3-phosphate dehydrogenase gapn2 from methanocaldococcus jannaschii dsm 2661 37 d1ad3a_ not modelled 100.0 25 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 38 c3v4cB_ not modelled 100.0 25 PDB header:oxidoreductase Chain: B: PDB Molecule:aldehyde dehydrogenase (nadp+); PDBTitle: crystal structure of a semialdehyde dehydrogenase from sinorhizobium2 meliloti 1021 39 d1ez0a_ not modelled 100.0 19 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 40 c3lnsD_ not modelled 100.0 24 PDB header:oxidoreductase Chain: D: PDB Molecule:benzaldehyde dehydrogenase; PDBTitle: benzaldehyde dehydrogenase, a class 3 aldehyde dehydrogenase, with2 bound nadp+ and benzoate adduct 41 c3k9dD_ not modelled 100.0 16 PDB header:oxidoreductase Chain: D: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of probable aldehyde dehydrogenase from listeria2 monocytogenes egd-e 42 d1o20a_ not modelled 100.0 15 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 43 c3my7A_ not modelled 100.0 18 PDB header:oxidoreductase Chain: A: PDB Molecule:alcohol dehydrogenase/acetaldehyde dehydrogenase; PDBTitle: the crystal structure of the acdh domain of an alcohol dehydrogenase2 from vibrio parahaemolyticus to 2.25a 44 c2h5gA_ not modelled 100.0 17 PDB header:oxidoreductase Chain: A: PDB Molecule:delta 1-pyrroline-5-carboxylate synthetase; PDBTitle: crystal structure of human pyrroline-5-carboxylate synthetase 45 d1vlua_ not modelled 100.0 17 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 46 c1vluB_ not modelled 100.0 17 PDB header:oxidoreductase Chain: B: PDB Molecule:gamma-glutamyl phosphate reductase; PDBTitle: crystal structure of gamma-glutamyl phosphate reductase (yor323c) from2 saccharomyces cerevisiae at 2.40 a resolution 47 d1k75a_ not modelled 98.3 16 Fold:ALDH-like Superfamily:ALDH-like Family:L-histidinol dehydrogenase HisD 48 c3oqbF_ not modelled 25.6 8 PDB header:oxidoreductase Chain: F: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of putative oxidoreductase from bradyrhizobium2 japonicum usda 110 49 d1h6da1 not modelled 23.9 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 50 d2ioja1 not modelled 21.9 14 Fold:MurF and HprK N-domain-like Superfamily:HprK N-terminal domain-like Family:DRTGG domain 51 c2ec4A_ not modelled 20.7 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:fas-associated factor 1; PDBTitle: solution structure of the uas domain from human fas-2 associated factor 1 52 c1sazA_ not modelled 19.9 21 PDB header:transferase Chain: A: PDB Molecule:probable butyrate kinase 2; PDBTitle: membership in the askha superfamily: enzymological2 properties and crystal structure of butyrate kinase 2 from3 thermotoga maritima 53 d1lc0a1 not modelled 15.9 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 54 c2yukA_ not modelled 15.8 19 PDB header:transferase Chain: A: PDB Molecule:myeloid/lymphoid or mixed-lineage leukemia PDBTitle: solution structure of the hmg box of human myeloid/lymphoid2 or mixed-lineage leukemia protein 3 homolog 55 d1t0tv_ not modelled 15.5 7 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Chlorite dismutase-like 56 d1wo8a1 not modelled 15.2 14 Fold:Methylglyoxal synthase-like Superfamily:Methylglyoxal synthase-like Family:Methylglyoxal synthase, MgsA 57 d1vdha_ not modelled 15.0 21 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Chlorite dismutase-like 58 d1k99a_ not modelled 14.4 6 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 59 c1j3xA_ not modelled 14.3 6 PDB header:dna binding protein Chain: A: PDB Molecule:high mobility group protein 2; PDBTitle: solution structure of the n-terminal domain of the hmgb2 60 d1j3xa_ not modelled 14.3 6 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 61 c2eqzA_ not modelled 14.2 5 PDB header:transcription Chain: A: PDB Molecule:high mobility group protein b3; PDBTitle: solution structure of the first hmg-box domain from high2 mobility group protein b3 62 c2crjA_ not modelled 13.8 13 PDB header:gene regulation Chain: A: PDB Molecule:swi/snf-related matrix-associated actin- PDBTitle: solution structure of the hmg domain of mouse hmg domain2 protein hmgx2 63 c2yvqA_ not modelled 12.9 16 PDB header:ligase Chain: A: PDB Molecule:carbamoyl-phosphate synthase; PDBTitle: crystal structure of mgs domain of carbamoyl-phosphate2 synthetase from homo sapiens 64 c3fd8A_ not modelled 12.8 13 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of an oxidoreductase from enterococcus2 faecalis 65 c3fghA_ not modelled 12.6 3 PDB header:transcription Chain: A: PDB Molecule:transcription factor a, mitochondrial; PDBTitle: human mitochondrial transcription factor a box b 66 c3jtpB_ not modelled 12.5 17 PDB header:protein binding Chain: B: PDB Molecule:adapter protein meca 1; PDBTitle: crystal structure of the c-terminal domain of meca 67 c2co9A_ not modelled 12.1 10 PDB header:transcription Chain: A: PDB Molecule:thymus high mobility group box protein tox; PDBTitle: solution structure of the hmg_box domain of thymus high2 mobility group box protein tox from mouse 68 c1vjtA_ not modelled 11.9 12 PDB header:hydrolase Chain: A: PDB Molecule:alpha-glucosidase; PDBTitle: crystal structure of alpha-glucosidase (tm0752) from thermotoga2 maritima at 2.50 a resolution 69 c2iswB_ not modelled 11.3 8 PDB header:lyase Chain: B: PDB Molecule:putative fructose-1,6-bisphosphate aldolase; PDBTitle: structure of giardia fructose-1,6-biphosphate aldolase in2 complex with phosphoglycolohydroxamate 70 c2qguA_ not modelled 11.2 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:probable signal peptide protein; PDBTitle: three-dimensional structure of the phospholipid-binding protein from2 ralstonia solanacearum q8xv73_ralsq in complex with a phospholipid at3 the resolution 1.53 a. northeast structural genomics consortium4 target rsr89 71 d1sgva1 not modelled 11.1 26 Fold:PUA domain-like Superfamily:PUA domain-like Family:PUA domain 72 c3cxjB_ not modelled 10.9 20 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an uncharacterized protein from2 methanothermobacter thermautotrophicus 73 c3e7hA_ not modelled 10.8 21 PDB header:transferase Chain: A: PDB Molecule:dna-directed rna polymerase subunit beta; PDBTitle: the crystal structure of the beta subunit of the dna-2 directed rna polymerase from vibrio cholerae o1 biovar3 eltor 74 c3ec7C_ not modelled 10.5 18 PDB header:oxidoreductase Chain: C: PDB Molecule:putative dehydrogenase; PDBTitle: crystal structure of putative dehydrogenase from salmonella2 typhimurium lt2 75 d2lefa_ not modelled 10.5 8 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 76 d1vkna1 not modelled 10.4 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 77 c3evnA_ not modelled 10.4 5 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of putative oxidoreductase from streptococcus2 agalactiae 2603v/r 78 c3tfwB_ not modelled 10.4 10 PDB header:transferase Chain: B: PDB Molecule:putative o-methyltransferase; PDBTitle: crystal structure of a putative o-methyltransferase from klebsiella2 pneumoniae 79 c3db2C_ not modelled 9.9 24 PDB header:oxidoreductase Chain: C: PDB Molecule:putative nadph-dependent oxidoreductase; PDBTitle: crystal structure of a putative nadph-dependent oxidoreductase2 (dhaf_2064) from desulfitobacterium hafniense dcb-2 at 1.70 a3 resolution 80 d1s7ia_ not modelled 9.8 14 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:DGPF domain (Pfam 04946) 81 d1ydwa1 not modelled 9.6 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 82 d1ryda1 not modelled 9.5 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 83 c2p2sA_ not modelled 9.4 8 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of putative oxidoreductase (yp_050235.1) from2 erwinia carotovora atroseptica scri1043 at 1.25 a resolution 84 d2dlxa1 not modelled 9.1 8 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:UAS domain 85 c2q4eB_ not modelled 8.8 13 PDB header:oxidoreductase Chain: B: PDB Molecule:probable oxidoreductase at4g09670; PDBTitle: ensemble refinement of the protein crystal structure of gene product2 from arabidopsis thaliana at4g09670 86 d1lwma_ not modelled 8.8 11 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 87 c2cs1A_ not modelled 8.7 11 PDB header:dna binding protein Chain: A: PDB Molecule:pms1 protein homolog 1; PDBTitle: solution structure of the hmg domain of human dna mismatch2 repair protein 88 c2ze3A_ not modelled 8.6 14 PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus 89 c2ixaA_ not modelled 8.6 9 PDB header:hydrolase Chain: A: PDB Molecule:alpha-n-acetylgalactosaminidase; PDBTitle: a-zyme, n-acetylgalactosaminidase 90 d1saza2 not modelled 8.5 20 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Acetokinase-like 91 d1hsma_ not modelled 8.3 18 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 92 c3labA_ not modelled 8.3 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate) PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica 93 d1zh8a1 not modelled 8.2 18 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 94 c3nt5B_ not modelled 8.2 21 PDB header:oxidoreductase Chain: B: PDB Molecule:inositol 2-dehydrogenase/d-chiro-inositol 3-dehydrogenase; PDBTitle: crystal structure of myo-inositol dehydrogenase from bacillus subtilis2 with bound cofactor and product inosose 95 c2vxhF_ not modelled 8.0 17 PDB header:oxidoreductase Chain: F: PDB Molecule:chlorite dismutase; PDBTitle: the crystal structure of chlorite dismutase: a detox enzyme2 producing molecular oxygen 96 c3mtjA_ not modelled 7.9 13 PDB header:oxidoreductase Chain: A: PDB Molecule:homoserine dehydrogenase; PDBTitle: the crystal structure of a homoserine dehydrogenase from thiobacillus2 denitrificans to 2.15a 97 d1v64a_ not modelled 7.8 8 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 98 d1hmfa_ not modelled 7.6 17 Fold:HMG-box Superfamily:HMG-box Family:HMG-box 99 c1hmfA_ not modelled 7.6 17 PDB header:dna-binding Chain: A: PDB Molecule:high mobility group protein fragment-b; PDBTitle: structure of the hmg box motif in the b-domain of hmg1

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0