|   |
152 | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | |
|
. | . | 170 | . | . | . | . | . | . | . | |
|
|
. | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | Y | T | P | D | I | L | R | C | R | K | S | G | V | L | T | . |
. |
G | L | P | D | A | Y | G | R | G | R | . |
. |
. |
I | I | G | D | Y | R | R | V | A | L | Y | G | I | D | Y | L | M | K | D | K | L | A | Q | F | T | S | L | Q | A | D | L | E | N | G | V | N | L | E | Q | T | I | R | L | R | E | E | I | A | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   | . | . |
|
|   |   |   |   |
|   |
|   | . | . | . |
|
|   |
|
|   |
|   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|
|   |   |
|   |   |
|
|   |   |
|   |
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
M | V | P | S | F | I | M | K | A | H | E | S | G | I | I | H | V | H | D | I | D | Y | S | P | A | L | P | F | T | N | C | C | L | V | D | L | K | G | M | L | E | N | G | F | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 | S |
|  |  |  |  |  |  |  |  |  | T | S |  |  |  | T | T | T | T | T | T | T | T | S |
|
|
|
|
|  |  |
|
|  |  |  |  |  |  | S |
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
49 | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
227 | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
Q | H | R | A | L | G | Q | M | K | E | M | A | A | K | Y | G | Y | D | I | S | G | P | A | T | N | A | Q | E | A | I | Q | W | T | Y | F | G | Y | L | A | A | V | K | S | Q | N | G | A | A | M | S | F | G | R | T | S | T | F | L | D | V | Y | I | E | R | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |
|
|
|
|   |   |
|
|   |
|
|   |   |   |   |
|   |
|
|   |   |
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|
|
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |
| . |
|
|
|   |   |   |
|
|   |   |
|
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | G | N | A | Q | I | E | T | P | K | S | I | G | V | A | T | A | I | M | A | Q | I | T | A | Q | V | A | S | H | Q | Y | G | . |
G | T | T | F | A | N | V | D | K | V | L | S | P | Y | V | K | R | T | Y | A | K | H | I | E | D | A | E | K | W | Q | I | A | D |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |  | T | T |  |  |  |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | S | . |
|  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
94 | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | |
. | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
292 | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | |
|
|
. | . | . | . | . | . | . | 360 | . | . | . | |
|
Predicted Secondary structure |   |
. | . | . |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  | . | . | . |  |  |  |  |  |  |  |  |  |  |  | . | . |
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
. |
Query Sequence |   |
. |
. |
. |
L | K | A | G | K | I | T | E | Q | E | A | Q | E | M | V | D | H | L | V | M | K | L | R | M | V | R | F | L | R | T | P | E | Y | D | E | L | F | S | G | D | P | I | W | A | T | E | S | I | G | G | M | G | L | D | G | R | T | L | V | T | K | . |
. |
. |
N | S | F | R | F | L | N | T | L | Y | T | . |
. |
Query Conservation |   |
. | . | . |
|
|   |
|   |
|
|   |
|
|
|   |
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |
|
|
|
|
|   |   |   |
|
|   |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|   |   |   | . | . |
Alig confidence |   |
. | . | . |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |   |
|   |   |   | . |
|   |   |   |
|   |
|   |   |
|   |
|   |
|   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |
|
|   |
|
|
|   |
|
|   | . | . | . | . | . | . |
|   |   |   |   |   |
|   |
|   |
|   |
|
|
|
|   |
|   |   |   |
|   |
Template Sequence |   |
A | L | N | Y | A | Q | S | K | . |
T | E | K | D | V | Y | D | A | F | Q | A | Y | E | Y | E | V | N | T | L | F | S | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
N | G | Q | T | P | F | V | T | I | T | F | . |
. |
. |
. |
. |
. |
G | T | G | T | D | W | T | E | R | M | I | Q | K | A | I | L | K | N | R | I | K | G | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | . | . | . | . | . | . | . | . | . | T | S | S |
|
|
|  |  |  |  |  | . | . | . | . | . | . |
|
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| B |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
159 | 160 | . | . | . | . | . | . | |
. | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | 190 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . |
  |
  |   |
|
|
364 | . | . | . | . | . | |
370 | . | . | . | . | . | . | . | . | . | 380 | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | |
. | . | . | . | . | . | . | . | . | 420 | . | |
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
. | . |  |
|
|
|
|
| . |
|  |  |  |  |  |  |
|
|
|
|
|  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  | . |  |
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
. |
. |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
. |
. |
M | G | P | S | P | E | . |
P | N | M | T | I | L | W | S | E | K | L | P | L | . |
. |
. |
. |
. |
. |
. |
N | F | K | K | F | A | A | K | V | S | I | D | T | S | S | L | Q | Y | E | N | D | D | L | M | R | P | D | F | . |
N | N | D | D | Y | A | I | A | C | C | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
. | . |
|   |   |
|   |
| . |
|
|
|
|
|
|   |
|   |   |
|
|
| . | . | . | . | . | . | . |   |
|
|   |   |   |   |
|   |   |   |
|   |
|   |
|   |   |   |
|
|
|
|
|
|
|   |
| . |   |
|
|
|
|
|
|   |
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
. | . |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |
|   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |
|   |   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |
|
Template Sequence |   |
G | R | D | G | I | T | P | I | F | P | K | L | V | M | F | V | E | E | G | V | N | L | Y | K | D | D | P | N | Y | D | I | K | Q | L | A | L | E | C | A | S | K | R | M | Y | P | D | I | I | S | A | K | N | N | K | A | I | T | G | S | S | V | P | V | S | P | M | G | C | R | S | F | L | S | V | W | K | D | S | T | G |
Template Known Secondary structure |   |
T | T | T | T | B |
|
| S |
| S |  |  |  |  |  |  |
| T | T | T | T | S | S | T | T | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S |
|
|
|
| B | T | T | T | B |
|
|
|
|
| B |
| T | T | S |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
223 | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . |
  |
  |   |
422 | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | P | M | I | V | G | K | Q | M | Q | F | F | G | A | R | A | N | L | A | K | T | M | L | Y | A | I | N | G | G | V | D | E | K | L | K | M | Q | V | G | P | K | S | E | P | I | K | G | D | V | . |
. |
. |
. |
. |
L | N | Y | D | E | V | M | E | R | M | D | H | F | M | D | W | L | A | K | Q | Y | I | T | A | L | N |
Query Conservation |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |
|
|
|
|   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
| . |   |
|
|   |   |
|
|
|
|
|
|
|
|
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |   |
|   |   |   |
|
|
|
|   |   |   |
|   |   |
|   |   |
Template Sequence |   |
N | E | I | L | D | G | . |
R | N | N | L | G | V | V | T | L | N | L | P | R | I | A | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | S | Y | I | G | T | Q | F | N | E | Q | K | F | V | E | L | F | N | E | R | M | D | L | C | F | E | A | L | M | C | R | I | S |
Template Known Secondary structure |   |
| B |
|
| T | T | . |
| B |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T |  |  | T | T |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
303 | . | . | . | . | . | |
. | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . |
  |
  |   |
497 | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | I | H | Y | M | H | D | K | Y | S | Y | E | A | S | L | M | A | L | H | D | R | D | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | R | T | M | A | C | G | I | A | G | L | S | V | A | A | D | S | L | S | A | I | K | Y | A | K | V | K | P | I | R | D | E | D | G | L | A | I | D | F | E | I | E | G | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |
|   |   |   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|
|
|   |
|   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
S | L | K | G | V | K | A | T | V | A | P | I | L | Y | Q | E | G | A | F | G | V | R | L | K | P | D | D | D | I | I | E | L | F | K | N | G | R | S | S | V | S | L | G | Y | I | G | I | H | E | L | N | I | L | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 | T | T | T |
| B | G | G | G |
|  |  |  |  | T | S | S | T | T | S | S |
|
|
| T | T | S | B | T |  |  |  |  | T | T | T | T | S |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
358 | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
564 | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | P | Q | F | G | N | N | D | P | R | V | D | D | L | A | V | D | L | V | E | R | F | M | K | K | I | Q | K | L | H | T | Y | R | D | A | I | P | T | Q | S | V | L | T | I | T | S | N | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
V | Y | G | K | K | T | G | N | T | P | D | G | R | R | A | G | A | P | F | G | P | G | A |
Query Conservation |   |
  |
|
|
|
|
|
|
|
|   |
|
|   |
|
|   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|
|
|   |   |   |   |
|   |   |
|   |
|   |   |
| . | . | . | . | . | . | . | . | . |   |   |
|   |   |
|
|
|
|
|
|
|
|   |
|
|   |
|
|
|   |
|   |
Alig confidence |   |
. | . | . | . |
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
. | . | . | . |
|   |   | . | . | . | . | . | . |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|
|   |   |
|
|
|
|
|   |   |   |
|
|
|
|   |
|   |   |   |
|
|   |
|   |   |   |   |
|   |   | . | . | . | . | . | . |
|
|
|
|
|
Template Sequence |   |
. |
. |
. |
. |
G | R | D | . |
. |
. |
. |
. |
. |
I | G | R | E | I | L | T | K | M | N | A | H | L | K | Q | W | T | E | R | T | G | F | A | F | S | L | Y | S | T | P | A | E | N | L | C | Y | R | F | C | K | L | D | T | E | K | Y | G | S | V | K | D | V | T | D | K | G | . |
. |
. |
. |
. |
. |
W | Y | T | N | S |
Template Known Secondary structure |   |
. | . | . | . | T | S |
| . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | T | T | T | T | S | . | . | . | . | . | . |
|
|
|
| T |
Template Predicted Secondary structure |   |
. | . | . | . |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
412 | . | . | |
|
|
|
|
|
. | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | |
|
|
|
|
|
. | . | . | . | . |
  |
  |   |
635 | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | P | M | H | G | R | D | Q | K | G | A | V | A | S | L | T | S | V | A | K | L | P | F | A | Y | A | K | D | G | I | S | Y | T | F | S | I | V | P | N | A | L | G | K | D | D | E | V | R | K | T | N | L | A | G | L | M | D | G | Y | F | H | H | E | A | S | I | E | G | G | Q | H | L | N | V | N |
Query Conservation |   |
|
|   |   |
|
|
|   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|   |   |   |   |   |   |
|   |   |
|
|   |
|
|   |
|   |   |
|   |   |   |   |
|   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|   |   |
|   |   |   |
|
|   |
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |   | . |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   | . | . | . | . | . | . |
|   |   |   |
|   |   |
|
|   |   |
|
|   |   |   |   |   | . | . | . | . | . | . |   |
|   |
|   |   |
|
|
Template Sequence |   |
F | H | V | S | V | E | E | N | I | T | P | F | E | K | I | S | R | E | A | P | Y | . |
H | F | I | A | T | G | G | H | I | S | Y | V | E | L | P | . |
. |
. |
. |
. |
. |
D | M | K | N | N | L | K | G | L | E | A | V | W | D | Y | A | A | Q | . |
. |
. |
. |
. |
. |
H | L | D | Y | F | G | V | N |
Template Known Secondary structure |   |
T |
|
|
| T | T | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |  | T | T |
| T | T | B |
|
|  |  |  |  |
|
| . | . | . | . | . | . |
|
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |
| S |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
| . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
476 | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | |
. | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
530 | . | . | . | . | . | . | . |
  |