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Job DescriptionP24240
Confidence99.61%DateThu Jan 5 11:41:32 GMT 2012
Rank89Aligned Residues272
% Identity16%Templatec3lpgA_
PDB info PDB header:hydrolase/hydrolase inhibitorChain: A: PDB Molecule:beta-glucuronidase; PDBTitle: structure of e. coli beta-glucuronidase bound with a novel, potent2 inhibitor 3-(2-fluorophenyl)-1-(2-hydroxyethyl)-1-((6-methyl-2-oxo-1,3 2-dihydroquinolin-3-yl)methyl)urea
Resolution2.42 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   71........80.........90.........100.........110.........120.........130.........140.........
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Query Sequence  HRYKEDIALMAEMGFKVFRTSIAWSRLFPQGDEITPNQQGIAFYRSVFEECKKYGIEPLVTLCHFDVPMHLVTEYGSWR.
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Template Sequence  VLXVHDHALXDWIGANSYRTSHYPYA. . . . . . . . . . . . . . . . . . EEXLDWADEHGIVVIDETAAVGFNLSLGIGFEAGNK
Template Known Secondary structure  T


TTS


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B


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   309310.........320.........330.... .....340.........350.........360.........370
 
   150.........160.........170. ........180.........190.........200.........210.......
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Query Sequence  . . . . . . . . . . NRKLVEFFSRYARTCFEAFDGL. . VKYWLTFNEINIMLHSPFSGAGLVFEEGENQDQVKYQAAHHQLVAS
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Template Sequence  PKELYSEEAVNGETQQAHLQAIKELIARDKNHPSVVXWSIANEPDTRPQ. . . . . . . . . . . . . . . . . . . . . . . . . GAREYF
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S
SSBTTTB
TT
TT




ST.........................
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   371........380.........390.........400.........410......... 420.....
 
   218.220.........230.........240.........250.........260.........270.........280.........290.......
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Query Sequence  ALATKIAHEVNPQNQVGCMLAGGNFYPYSCKPEDVWAALEKDRENLFFIDVQARGTYPAYSARVFREKGVTINKAPGDDE
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Template Sequence  APLAEATRKLDPTRPITCVNV. XFCDAHTDTISDL. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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SSS
B
.TTS
TTT
SSGGG.............................................
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   426...430.........440...... ...450.........
 
   298.300.........310.........320.........330.........340.........350.........360.........370.......
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Query Sequence  ILKNTVDFVSFSYYASRCASAEMNANNSSAANVVKSLRNPYLQVSDWGWGIDPLGLRITMNMMYDRYQKPLFLVENGLGA
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Template Sequence  . . . . . FDVLCLNRY. . . . . . . . . . . . . . . . . . . . . . . . . YGWYVQSGDLETAEKVLEKELLAWQEKLHQPIIITEYGVDT
Template Known Secondary structure  .....SSS

.........................BTTTBSTT








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   460........ .470.........480.........490.........500.........
 
   378.380.........390.........400.........410.........420..... ....430.........440.........450....
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Query Sequence  KDEFAANGEINDDYRISYLREHIRAMGEAIADGIPLMGYTTWGCIDLV. . . SASTGEMSKRYGFVFVDRDDAGNGTLTRT
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Template Sequence  LAGLHSXYTDXWSE. . EYQCAWLDXYHRVFDRVSAVVGEQVWNFADFATSQGILRV. GGNKKGIF. . . . . . . . . . TRDRK
Template Known Secondary structure 
TT


TT

TTS..TT
TTS
B
B

BTTBS.SSB

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   510.........520... ......530.........540.........550.........560... ......570. .....
 
   455....460.........470....
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Query Sequence  RKKSFWWYKKVIASNGEDLE
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Template Sequence  PKSAAFLLQKRWTGXNFGEK
Template Known Secondary structure  B
TS
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   577..580.........590......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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