|   |
74 | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | |
|
|
. | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
| . | . | . |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | E | D | I | A | L | M | A | E | M | G | F | K | V | F | R | T | S | I | A | W | S | R | L | F | P | Q | G | D | E | I | T | P | N | Q | Q | G | I | A | F | Y | R | S | V | F | E | E | C | K | K | Y | G | I | E | P | L | V | T | L | C | H | . |
. |
. |
F | D | V | P | M | H | L | V | T | E | Y | G | S | W | R | N |
Query Conservation |   |
  |
|
|
|   |
|   |   |   |
|
|   |   |   |
|
|
|
|
|   |
|
|
|
|   |
|   |
|   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|   |
|
|
|
|
|   |
| . | . | . |
|
|
|
|   |   |
|   |   |   |   |
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|
|
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|   |
|
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |
Template Sequence |   |
Q | D | X | X | T | F | L | X | Q | N | G | F | N | A | V | R | I | P | V | T | W | Y | E | H | X | D | A | E | . |
. |
G | N | V | D | E | A | W | X | X | R | V | K | A | I | V | E | Y | A | X | N | A | G | L | Y | A | I | V | N | V | H | H | D | T | A | A | G | S | G | A | W | I | . |
. |
K | A | D | T | D | V | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |
|
|
|
| G | G | G | B |
| T | T | . | . |
|
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |
|
| T | T | B | S | S | S | T | T |
|
| B | . | . |
| S | S |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
55 | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | |
|
. | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | |
|
. | . | . | . | . | . | 130 |
  |
  |   |
151 | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | |
|
. | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | K | L | V | E | F | F | S | R | Y | A | R | T | C | F | E | A | F | D | G | L | . |
. |
V | K | Y | W | L | T | F | N | E | I | N | I | M | L | H | S | P | F | S | G | A | G | L | V | F | E | E | G | E | N | Q | D | Q | V | K | Y | Q | A | A | H | H | Q | L | V | A | S | A | L | A | T | K | I | A | H | E | V | N |
Query Conservation |   |
  |   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |
|
|
|
| . | . |
|   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |
|
|   |   |
|
|   |
|
|
|   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|
Template Sequence |   |
A | A | T | K | E | K | F | K | K | L | W | T | Q | I | A | N | A | L | A | D | Y | D | Q | H | L | L | F | E | G | Y | N | E | X | L | D | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | N | S | W | D | E | P | Q | K | A | S | G | Y | E | A | L | N | N | Y | A | Q | D | F | V | D | A | V | R | A | T | G | G | N | N |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | S |
| T | T |  |  |  |  |
|
| S |
|
|
|
| T | . | . | . | . | . | . | . | . | . | . | T |
|
| S | S | S |
| S | S | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| G | G | G |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
131 | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 |
  |
  |   |
229 | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | Q | N | Q | V | G | C | M | L | A | G | G | N | F | Y | P | Y | S | C | K | P | E | D | V | W | A | A | L | E | K | D | R | E | N | L | F | F | I | D | V | Q | A | R | G | T | Y | P | A | Y | S | A | R | V | F | R | E | K | G | V | T | I | N | K | A | P | G | D | D | E | I | L | K | N | T | V | D | F | V | S | F |
Query Conservation |   |
  |   |   |   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |
|   |
Template Sequence |   |
A | T | R | N | L | I | V | N | T | Y | A | A | A | K | G | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | V | L | N | N | F | X | L | P | T | D | A | . |
. |
. |
. |
. |
. |
. |
. |
V | N | N | H | L | I | V | Q | V |
Template Known Secondary structure |   |
G | T |
|
|  |  |  |  |
| G | G | G |
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  | T |
|
|
|
|
|
| S | . | . | . | . | . | . | . | . | S | S | S |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
201 | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 220 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | 230 | . | . | . | . | . | . | . |
  |
  |   |
309 | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | |
. | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | Y | Y | A | S | R | C | A | S | A | E | M | N | A | N | N | S | S | A | A | N | V | V | K | S | L | R | N | P | Y | L | Q | V | S | D | W | G | W | G | I | D | P | L | G | L | R | I | T | M | N | M | M | Y | D | R | Y | . |
Q | K | P | L | F | L | V | E | N | G | L | G | A | K | D | E | F | A | A | N | G | E | I |
Query Conservation |   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |
|   |
|
|   |   |   |
|   |   |   |   |   |
|
| . |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
H | S | Y | D | P | W | N | F | F | N | T | K | T | T | W | D | S | E | C | H | N | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | T | E | I | F | S | A | L | S | K | K | F | T | T | I | P | Y | I | I | G | E | Y | G | T | H | G | E | S | D | I | S | V | S | K | S | S |
Template Known Secondary structure |   |
 |  |
|
| S | T | T |  |  |  |  |
| S | S |
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
| S | S | S |
|  |  |  |  |  |  |
| S |
|
| G | G | G |
|
|
|
| T | T | S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
238 | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . |
  |
  |   |
388 | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | D | D | Y | R | I | S | Y | L | R | E | H | I | R | A | M | G | E | A | I | A | D | G | I | P | L | M | G | Y | T | T | W | G |
Query Conservation |   |
  |
|   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |
|
|   |
|
|
|   |
|   |
|
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   | . | . | . |   |   |   |   |
|   |
Template Sequence |   |
P | A | E | K | I | K | L | A | A | D | Q | A | A | D | X | V | K | L | A | K | D | H | H | S | . |
. |
. |
A | T | F | Y | W | X |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . | . | . |
|  |  |  |  | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
296 | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | |
|
|
320 | . | . | . | . | . |
  |