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Job DescriptionP11875
Confidence100.00%DateThu Jan 5 11:32:57 GMT 2012
Rank29Aligned Residues410
% Identity21%Templatec1wkbA_
PDB info PDB header:ligaseChain: A: PDB Molecule:leucyl-trna synthetase; PDBTitle: crystal structure of leucyl-trna synthetase from the2 archaeon pyrococcus horikoshii reveals a novel editing3 domain orientation
Resolution2.05 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   83......90.........100.........110.........120.........130.........140.........150.........160..
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Query Sequence  INIFLDPAFLAEHVQQALASDRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDW
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Template Conservation       

      
     
           

 
   


 

 




     
 

  

 

 
  
    


  
Template Sequence  LNFKAIEEKWQKRWLEAKIFEPNIRDKPKEKKFYITVAFPYLSGHLHVGHARTYTIPDVIARFKRMQGYNVLFPMAWHIT
Template Known Secondary structure 


TTTT


GGGS
GGG


BTTS

BT




BB

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   4.....10.........20.........30.........40.........50.........60.........70.........80...
 
   163......170.........180.........190.........200.........210.........220.........230.........240..
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Query Sequence  GTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQIT
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Template Sequence  GSPIVGIAERIKNRDPK. . . . . . . . . . . . . . . . . . . . . . . . . . . TIWIYRDVYKVPEEILWTFEDPINIVKYFMKAAKET
Template Known Secondary structure  BSTT
...........................TS


GGGS
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   84.....90.........100 .........110.........120.........130......
 
   243......250.........260 .........270.........280........
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Query Sequence  YDRLNVTLTRDDVMGESL. . . . YNPMLPGIVADLKAKGLAVESEGATVVF. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  FIRAGFSVDWSREFYTTSLFPPFSKFIEWQFWKLKEKGYIVKGAHRVRWDPVVGTPLGDHDLMEGEDVPILDYIIIKFEL
Template Known Secondary structure  TT



GGG

B
STTSTT
TTTT

TT

SB
SS


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   137..140.........150.........160.........170.........180.........190.........200.........210......
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation          
 
 

 
 

       
 
   
                                      
  
 
   
Template Sequence  RENGEVIYLPAATLRPETVYGVTNMWVNPNATYVKAKVRRKDKEETWIVSKEAAYKLSFQDREIEVIEEFKGEKLIGKYV
Template Known Secondary structure 
SS
S

S
GGGGGG


TTS
TTTTSS

TTTTTTT
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   217..220.........230.........240.........250.........260.........270.........280.........290......
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation    
       
     
    


 
   


   
                                  
         
Template Sequence  RNPVSGDEVIILPAEFVDPDNATGVVMSVPAHAPFDHVALEDLKRETEILEKYDIDPRIVFPAVEEVNKLGIKSQKDKEK
Template Known Secondary structure 
SSS


TTS
TTSTTS

TTT



S

S


TT
S







TT

SGGGTS


TT
S
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   297..300.........310.........320.........330.........340.........350.........360.........370......
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation                          
         
   
   
                      
     



     
Template Sequence  LEQATKTIYKAEYHKGIFKVPPYEGKPVQEVKEAIAKEMLEKGIAEIMYEFAEKNVISRFGNRAVIKIIHDQWFIDYGNP
Template Known Secondary structure  TS

SGGGTTTTTSSSS

B
TTS
B

TT
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   393......400.........410.........420.........430.........440.........450.........460.........470..
 
   289290.........300.........310.........320......
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . LDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYE. . . . . . . . . . . .
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Template Sequence  EWKEKARKALERMKILPETRRAQFEAIIDWLDKKACARKIGLGTPLPWDPEWVIESLSDSTIYMAYYTISRHINKLRQEG
Template Known Secondary structure  TSSGGG



SSSBS
TT
TTTSSSSTT
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   473......480.........490.........500.........510.........520.........530.........540.........550..
 
   327..330.........340.........350.........360
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPE
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Template Conservation                                                    
 
    
 
                    
Template Sequence  KLDPEKLTPEFFDYIFLEEFSEDKEKELEKKTGIPAEIIHEMKEEFEYWYPLDWRCSGKDLIPNHLTFFIFNHVAIFREE
Template Known Secondary structure 


GGG

S


S


S
SGGGTTTS
GG
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   553......560.........570.........580.........590.........600.........610.........620.........630..
 
   361 ........370.........380.........390.........400.........410.........420.........430........
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Query Sequence  S. . VPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNR
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Template Sequence  HWPKGIAVNGFGTL. . . EGQKMSKSKGNVLNFIDAIEE. . . . . . . . . . . . . . . . . . . . . . . . . . . NGADVVRLYIMSLAE
Template Known Secondary structure  GS



...TTB


TTTT


B...........................


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   633......640...... ...650.........660....... ..670.........680..
 
   439440.........450.........460.........470.........480.........490.........500.........510.......
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Query Sequence  . TTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEIDEEQLAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPH
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Template Conservation     
  
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Template Sequence  HDSDFDWRRKEVGK. . . . . . . . LRKQIERFYELISQFAEYEVKGNVEL. . . . KDIDRWMLHRLNKAIKETTNALEEFRTR
Template Known Secondary structure  TT


........T



S



....
TT
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   683......690...... ...700.........710.........720.. .......730.........740.........750
 
   518.520..... ....530.........540.........550.........560...
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Query Sequence  VMCAYLYD. LAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLK
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Template Conservation   
   
   
      
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Template Sequence  TAVQWAFYSIMNDLRWYLRRTEGR. . DDEAKRYVLRTLADVWVRLMA
Template Known Secondary structure  TTTT
..

T
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   751........760.........770.... .....780.........790.....
 
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No model constructed - rank, confidence too low




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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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