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Job DescriptionP11875
Confidence100.00%DateThu Jan 5 11:32:57 GMT 2012
Rank25Aligned Residues393
% Identity22%Templatec1qu2A_
PDB info PDB header:ligase/rnaChain: A: PDB Molecule:isoleucyl-trna synthetase; PDBTitle: insights into editing from an ile-trna synthetase structure2 with trna(ile) and mupirocin
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   110.........120.........130.........140.........150.........160.........170.........180.........
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Query Sequence  PEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQFGMLIAWLEKQQQENAGEMELADL
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Template Sequence  KGNETFILHDGPPYANGNLHMGHALNKILKDFIVRYKTMQGFYAPYVPGWDTHGLPIEQALTKKGVDRKKMSTAE. . . . .
Template Known Secondary structure  TTS
B





BSSS


TTT
B




B

ST

STTT
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   45....50.........60.........70.........80.........90.........100.........110.........
 
   190.........200.........210.........220.........230.........240.........250. ........260.......
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Query Sequence  EGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQITYDRLNVTLT. . RDDVMGESLYNPMLPG
Query Conservation     
                       

                             
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Template Conservation  ..................................     
  
   
        



  

   
 
 
  
      
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . FREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYEAAQIR
Template Known Secondary structure  ..................................TTT

S
TTS
TTS
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   120.........130.........140.........150.........160.....
 
   268.270.........280. ........290........
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Query Sequence  IVADLKAKGLAVES. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . EGATVVFLDEFKNKEGE. . . . .
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Template Sequence  IFGEMADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFNVKDDKGVVDADAKFIIWTTTPWTIPSNVAITV
Template Known Secondary structure  TT
TTTT

GGG

B


SSTTGGGTT

B

S
GGGSS

B



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   166...170.........180.........190.........200.........210.........220.........230.........240.....
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation   
   
          
                           
  
 
     
       
     
    


 

Template Sequence  HPELKYGQYNVNGEKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEWVVAQHPFLDRESLVINGDHVTTDAGTGCVH
Template Known Secondary structure 
TT






TTTT




TTTT

SS








TTT
TT


B

TT

SB





SS

SSS
S


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   246...250.........260.........270.........280.........290.........300.........310.........320.....
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
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Template Sequence  TAPGHGEDDYIVGQQYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRTKKPVI
Template Known Secondary structure  B
TTS
STTTSSS







SSS


TT
SS
SSS
SSTTGGGSS



TTT

B
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   326...330.........340.........350.........360.........370.........380.........390.........400.....
 
   299300......... 310.........320......
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PMGVIIQKKDG. . . . GYLYTTTDIACAKYRYE. . . . . .
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Template Sequence  FRATPQWFASISKVRQDILDAIENTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAENGEIIMTKETVNHVAD
Template Known Secondary structure 
TSSS



S
SSS
B



TTS


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   406...410.........420.........430.........440.........450.........460.........470.........480.....
 
   327..330.........340.. .....
Predicted Secondary structure  ..........................................................








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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TLHADRVLYYIDSRQH. QHLMQ
Query Conservation  ..........................................................    
  
 
 
 
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Template Sequence  LFAEHGSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYRGWFNS
Template Known Secondary structure 
TS
SSTT


SS
TTS





TTTTTSTT

SSBSGGGGTT
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   486...490.........500.........510.........520.........530.........540.........550.........560.....
 
   348.350.........360.........370.........380.........390.........400.........410.........420.......
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Query Sequence  AWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKLANAVGIG
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Template Sequence  SITTSVATRGVSPYKFLLSHGF. . VMDGEGKKMSKSLGNVIVPDQVVKQ. . . . . . . . . . . . . . . . . . . . . . . . . . . KGAD
Template Known Secondary structure  SS
SBS

..
TTS



SSSS



...........................T
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   566...570.........580....... ..590.........600.........610.. ....
 
   428.430.........440.........450.........460.........470.........480.........490.........500.......
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Query Sequence  AVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEIDEEQLAAAPVIIREDREAQLAARLLQFEETL
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Template Sequence  IARLWVSSTDYLADVRISDEILKQ. TSDDYRKIRNTLRFMLGNINDFNPDTDSIPESEL. . . LEVDRYLLNRLREFTAST
Template Known Secondary structure  TS
TTS


.TSTT




GGGS...
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   617..620.........630.........640 .........650.........660.........670.... .....680.........690..
 
   508.510.........520......... 530.........540.........550.........560.........570....
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Query Sequence  TVVAREGTPHVMCAYLYDLAGL. . FSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGLDTLGIETV
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Template Sequence  INNYENFDYLNIYQEVQNFINVELSNFYLDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILV
Template Known Secondary structure  TT






TTS
TT
TTTS
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   693......700.........710.........720.........730.........740.........750.........760.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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