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Job DescriptionP11875
Confidence100.00%DateThu Jan 5 11:32:57 GMT 2012
Rank30Aligned Residues382
% Identity20%Templatec1obhA_
PDB info PDB header:synthetaseChain: A: PDB Molecule:leucyl-trna synthetase; PDBTitle: leucyl-trna synthetase from thermus thermophilus complexed2 with a pre-transfer editing substrate analogue in both3 synthetic active site and editing site
Resolution2.2 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   88.90.........100......... 110.........120.........130.........140.........150.........160.....
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Query Sequence  DPAFLAEHVQQALASDRLGVAT. . PEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQ
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Template Conservation      

      
               
  
    

 

 




       

  

 

 
  

   
 
 



Template Sequence  NPHAIEAKWQRFWEEKGFMKAKDLPGGGKQYVLVMFPYPSGDLHMGHLKNYTMGDVLARFRRMQGYEVLHPMGWDAFGLP
Template Known Secondary structure 

TTTTT


SS









SS
BT




B


S
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   5....10.........20.........30.........40.........50.........60.........70.........80....
 
   166...170.........180.........190.........200.........210.........220.........230.........240.....
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Query Sequence  FGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQITYDR
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Template Conservation 

  
 
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Template Sequence  AENAALKFGVHPKD. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . WTYANIRQAKESLRL
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   86...90......... 100.........110....
 
   246...250. ........260.........270.........280........
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Query Sequence  LNVTLT. . RDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVF. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  MGILYDWDREVTTCEPEYYRWNQWIFLKMWEKGLAYRAKEQWYLRITAYAERLLKDLEGLNWPEKVKAMQRAWIGRSEGA
Template Known Secondary structure  TT



GGG

BTTSTT



GGGGTTTT

S

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   115....120.........130.........140.........150.........160.........170.........180.........190....
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
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Template Sequence  EILFPVEGKEVRIPVFTTRPDTLFGATFLVLAPEHPLTLELAAPEKREEVLAYVEAAKRKTEIERQAEGREKTGVFLGAY
Template Known Secondary structure  BTT
S
S
GGGGGG


TT
TTTTTS

GGGTS
S
TTS


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   231........240.........250.........260.........270.........280.........290.........300.........310
 
  
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
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Template Sequence  ALNPATGERIPIWTADYVLFGYGTGAIMAVPAHDQRDYEFARKFGLPIKKVIERPGEPLPEPLERAYEEPGIMVNSGPFD
Template Known Secondary structure 
TTT

TTS
SSSTTS
GGG
T





BTTB


SS
SS


S


SSGGGT
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   311........320.........330.........340.........350.........360.........370.........380.........390
 
   289290.........300.....
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . LDEFKNKEGEPMGVIIQ. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  GTESEEGKRKVIAWLEEKGLGKGRVTYRLRDWLISRQRYWGTPIPMVHCVVPVPEEELPVLLPDLKDVEDISPLEAHPEF
Template Known Secondary structure  T
BTSS





SSS






GGG







S
STT

GGGG
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   391........400.........410.........420.........430.........440.........450.........460.........470
 
   306...310.........320......... 330.........340........ .350.........360
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Query Sequence  . . . . . . KKDGGYLYTTTDIACAKYRYETLH. . . . . . . . . . . . . . ADRVLYYIDSRQHQHLMQA. . . . . WAIVRKAGYVPE
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Template Conservation            



 



                          
 
  
 
 
               
         
Template Sequence  YETTCPKRDTDTMDTFFDSSWYYLRYTDPHNDRLPFDPEKANAWMPVDQYIGGVEHAVLHLLYSRFFTKFLHDLGMVKVE
Template Known Secondary structure 





B



TTTTSTT
SSSS


SBS

TT
TTS
S
S
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   480.........490.........500.........510.........520.........530.........540.........550.........
 
   361........370..... ....380.......
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Query Sequence  SVPLEHHMFGMMLGK. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DGKPFKTRAGGT
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Template Sequence  EPFQGLFTQGMVLAWTDFGPVEVEGSVVRLPEPTRIRLEIPESALSLEDVRKMGAELRPHEDGTLHLWKPAVMSKSKGNG
Template Known Secondary structure 
SBS



TT

T
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STT

TTSS

TTTT

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   566...570.........580.........590.........600.........610.........620.........630.........640.....
 
   388.390.........400.........410.........420.........430........ .440.........450.........460......
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Query Sequence  VKLADLLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNR. TTDYIFDWDNMLAFEGNTAPYMQYAYTR
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Template Sequence  VMVGPFVKE. . . . . . . . . . . . . . . . . . . . . . . . . . . QGADIARITILFAAPPENEMVWTEEGVQGAWR. . . . FLNRIYRR
Template Known Secondary structure 
B...........................S
S
TTS

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   646...650.... .....660.........670.........680...... ...690....
 
   467..470.........480.........490.........500.........510.........520.........530.........540......
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Query Sequence  VLSVFRKAEIDEEQLAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEE
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Template Sequence  VAEDREALLETSGVFQAEAL. . . EGKDRELYGKLHETLKKVTEDLEALRFNTAIAALMEFLNALYEYRKDRPVT. . . . . .
Template Known Secondary structure  TT





GGG
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TT
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   695....700.........710.... .....720.........730.........740.........750.........760.....
 
   547..550.........560.........
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Query Sequence  VRNSRLKLAQLTAKTLKLGLDTL
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Template Sequence  . . . . . . . . . PVYRTAIRYYLQML
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   766...770.........
 
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No model constructed - rank, confidence too low




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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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