|   |
25 | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | |
. | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | V | A | D | Y | I | P | A | L | A | T | V | D | G | S | R | L | G | I | A | I | C | T | V | . |
D | G | Q | L | F | Q | A | G | D | A | Q | E | R | F | S | I | Q | S | I | S | K | V | L | S | L | V | V | A | M | R | H | Y | S | E | E | E | I | W | Q | R | V | G | K | D | P | S | G | S | P | F | N | S | L | V | Q |
Query Conservation |   |
  |
|
|   |
|
|
|   |
|
|   |
|
|
|   |   |   |
|
|
|
|   |
|
| . |
|
|   |   |   |   |   |
|
|   |   |   |   |
|
|
|
|
|
|
|
|   |
|   |   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |
|
|   |
|
|
|
|   |   |
|
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |
| . |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |
|   |
|   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |
|   |   |   |
|   |
Template Sequence |   |
K | G | I | D | E | I | K | N | L | E | T | D | F | N | G | R | I | G | V | Y | A | L | D | T | G | S | G | K | S | F | S | Y | R | . |
A | N | E | R | F | P | L | C | S | S | F | K | G | F | L | A | A | A | V | L | K | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | Q | D | N | R | L | N | L | N | Q | I | V | N |
Template Known Secondary structure |   |
T | T |  |  |  |  |  |  |  |  |  |  |  | T | S |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  | S | . | T | T | S |
|  |  |
| G | G | G | G |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |  | T | T | S | S |
| T | T |
|  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
| . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
28 | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | |
. | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 90 | . | . | . | . | . |
  |
  |   |
104 | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | E | M | E | Q | G | I | P | R | N | P | F | I | N | A | G | A | L | V | V | C | D | M | L | Q | G | R | L | S | A | P | R | Q | R | M | L | E | V | V | R | G | L | S | G | V | S | D | I | S | Y | D | T | V | V | A | R | S | E | F | E | H | S | A | R | N | A | A | I | A | W | L | M | K | S | F | G | N | F | H | H |
Query Conservation |   |
|
|   |   |   |
|   |
|   |
|
|
|
|
|
|
|
|
|   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |
|
|   |
|
|
|   |   |
|
|   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|
| . | . | . | . | . | . |
|   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
Template Sequence |   |
Y | N | T | R | S | L | E | F | H | S | P | I | T | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
K | Y | K | D | N | G | M | S | L | G | D | M | A | A | A | A | L | Q | Y | S | D | . |
. |
. |
. |
. |
. |
N | G | A | T | N | I | I | L | E | R | Y | I | G | G | P | E | G | M | T | K | F | M | R | S | I | G | D | E | D | F |
Template Known Secondary structure |   |
| T | T | S |
|
|
| S | S |
|  |  |  |  | . | . | . | . | . | . | . | . | . |  | T | T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  | S |
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S |
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
97 | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
  |
  |   |
184 | . | |
|
|
|
. | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | |
|
Predicted Secondary structure |   |
|  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |
Query SS confidence |   |
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
Query Sequence |   |
D | V | . |
. |
. |
. |
T | T | V | L | Q | N | Y | F | H | Y | C | A | L | K | M | S | C | V | E | L | A | R | T | F | V | F | L | A | N | Q | G | K | A | I | H | I | D | E | P | V | V | T | P | M | Q | A | R | Q | I | N | A | L | M | A | T | S | G | M | Y | Q | N | A | G | E | F | A | W | R | V | G | L | P | . |
. |
Query Conservation |   |
|   | . | . | . | . |   |   |   |
|
|   |
|
|   |   |
|
|
|   |
|
|   |   |
|
|
|   |   |
|
|
|
|
|
|   |
|   |   |
|   |
|
|
|   |
|
|   |   |   |   |   |
|   |
|
|
|   |
|   |
|
|
|
|
|
|   |
|
|   |
|
|   |   |
|
|
|
| . | . |
Alig confidence |   |
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|   |
|
|   |   |
|   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | L | D | R | W | E | L | D | L | N | T | A | I | P | G | D | E | R | D | T | S | T | P | A | A | V | A | K | S | L | K | T | L | A | L | G | . |
. |
. |
. |
. |
. |
. |
. |
N | I | L | S | E | H | E | K | E | T | Y | Q | T | W | L | K | G | N | T | T | G | A | A | R | I | R | A | S | V | P | S | D | W | V | V | G |
Template Known Secondary structure |   |
B |
|
| S |
| T | T | G | G | G |
|
|
| T | T |
|
| T | T |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S | . | . | . | . | . | . | . | . | S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S |
| T | T | T | G | G | G | G | S |
| T | T | S |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . |
  |
  |   |
258 | . | 260 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 270 | |
|
. | . | |
|
. | . | . | . | . | . | . | |
|
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  | . | . | . | . | . |  |  |  |  |  | . | . |
|
| . | . |
|  |  |  |  |  |  | . | . |
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
| . |
. |
|
| . |
. |
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | K | S | G | V | G | G | G | . |
. |
. |
. |
. |
I | V | A | I | V | . |
. |
P | H | . |
. |
E | M | A | I | A | V | W | . |
. |
S | P | E | L | D | D | A | G | N | S | L | A | G | I | A | V | L | E | Q | L | T | K | Q | L | G |
Query Conservation |   |
|
|
|
|
|   |
|
| . | . | . | . | . |
|
|
|
|
| . | . |
|
| . | . |   |   |
|
|
|
|   | . | . |
|
|   |
|
|   |   |
|
|
|
|
|
|   |   |   |
|
|   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
| . | . |
|
| . | . |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|   |   |   |   |   |
|   |   |   |
|   |
|   |
|   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |
Template Sequence |   |
D | K | T | G | S | C | G | A | Y | G | T | A | N | D | Y | A | V | V | W | P | K | N | R | A | P | L | I | I | S | V | Y | T | T | K | N | E | K | E | A | K | H | E | D | K | V | I | A | E | A | S | R | I | A | I | D | N | L | K |
Template Known Secondary structure |   |
 |  |  |  |  |
| S | S | T | T |
|  |  |  |  |  |  |  |  |
| T | T | S |
|
|  |  |  |  |  |  |  |  |
| S |
| T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
233 | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 |
  |