Job Description P0AC13 Confidence 94.61% Date Thu Jan 5 11:16:53 GMT 2012 Rank 98 Aligned Residues 193 % Identity 16% Template c2cw6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Resolution 2.10 Å

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		32	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	T	H	N	S	L	I	D	A	V	K	H	A	N	L	M	I	N	A	G	A	T	I	I	D	V	G	G	E	S	T	R	P	G	A	A	E	V	S	V	E	E	E	L	Q	R	V	I	P	V	V	E	A	I	A	Q	R	F	E	V	W	I	S	V	D	T	S	K	P	E	V	I	R	E	S	A	K	V	G	A
Query Conservation
Alig confidence																																													.	.	.	.	.	.
Template Conservation																																													.	.	.	.	.	.
Template Sequence		K	N	I	V	S	T	P	V	K	I	K	L	I	D	M	L	S	E	A	G	L	S	V	I	E	T	T	S	F	V	S	P	K	W	V	P	Q	M	G	D	H	T	E	.	.	.	.	.	.	V	L	K	G	I	Q	K	F	P	G	I	N	Y	P	V	L	T	P	N	L	K	G	F	E	A	A	V	A	A	G	A
Template Known Secondary structure		S	S																	T	T		S										T	T	T		G	G	G	T	T				.	.	.	.	.	.					S				T	T		B							S										T	T
Template Predicted Secondary structure																																													.	.	.	.	.	.
Template SS confidence
		48	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90							.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.
		112	.	.	.	.	.	.	.	120	.	.	.																			.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.
Predicted Secondary structure														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		H	I	I	N	D	I	R	S	L	S	E	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	A	L	E	A	A	A	E	T	G	L	P	V	C	L	M	H	M	Q	G	N	P	K	T	M	Q	E	A	P	K	Y	D	D	V	F	A	E	V	N	R	Y	F	I	E	Q	I	A	R	C	E
Query Conservation														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																															.	.	.	.	.	.	.	.
Template Conservation																																																														.	.	.	.	.	.	.	.
Template Sequence		K	E	V	V	I	F	G	A	A	S	E	L	F	T	K	K	N	I	N	C	S	I	E	E	S	F	Q	R	F	D	A	I	L	K	A	A	Q	S	A	N	I	S	V	R	G	Y	V	S	C	A	L	G	C	P	Y	E	G	K	I	S	.	.	.	.	.	.	.	.	P	A	K	V	A	E	V	T	K	K	F	Y
Template Known Secondary structure		S								S									T	S	S		T	T	T															T	T									S	T	T		B	T	T	T	B	S			.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																														.	.	.	.	.	.	.	.
Template SS confidence
		122	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.									.	.	.	.	.	.	.	.	190	.	.	.
		174	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	A	G	I	A	K	E	K	L	L	L	D	P	G	F	G	F	G	K	N	L	S	H	N	Y	S	L	L	A	R	L	A	E	F	H	H	F	N	L	P	L	L	V	G	M	S	R	K	S	M	I	G	Q	L	L	N	V	G	P	S	E	R	L	S	G	S	L	A	C	A	V	I	A	A	M	Q	G	A	H	I
Query Conservation
Alig confidence							.	.										.																	.	.	.	.				.	.	.	.	.	.					.	.	.	.	.
Template Conservation							.	.										.																	.	.	.	.				.	.	.	.	.	.					.	.	.	.	.
Template Sequence		S	M	G	C	Y	.	.	E	I	S	L	G	D	T	I	G	.	V	G	T	P	G	I	M	K	D	M	L	S	A	V	M	Q	.	.	.	.	E	V	P	.	.	.	.	.	.	L	A	A	L	.	.	.	.	.	A	V	H	C	H	D	T	Y	G	Q	A	L	A	N	T	L	M	A	L	Q	M	G	V	S	V
Template Known Secondary structure			T	T		S	.	.							T	T		.																	.	.	.	.		S		.	.	.	.	.	.	G	G	G		.	.	.	.	.					B		T	T	S												T	T
Template Predicted Secondary structure							.	.										.																	.	.	.	.				.	.	.	.	.	.					.	.	.	.	.
Template SS confidence
		194	.	.	.	.			.	200	.	.	.	.	.	.	.		.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.					.	.	.							.	.	.	230						.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.
		254	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	R	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	D	S
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		256	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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