Return to main results Retrieve Phyre Job Id

Job DescriptionP30125
Confidence100.00%DateThu Jan 5 11:45:46 GMT 2012
Rank26Aligned Residues348
% Identity21%Templatec2qfyE_
PDB info PDB header:oxidoreductaseChain: E: PDB Molecule:isocitrate dehydrogenase [nadp]; PDBTitle: crystal structure of saccharomyces cerevesiae mitochondrial nadp(+)-2 dependent isocitrate dehydrogenase in complex with a-ketoglutarate
Resolution2.10 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   1........10.........20.........30.........40.........50.........60.........70.........80
Predicted Secondary structure 





























Query SS confidence 















































































Query Sequence  MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPK
Query Conservation 
     
 










      

 
        
       
       
  

  
       
  
 
    
 
Alig confidence 


..

























....












































Template Conservation     ..


 
 




 

   
        ....  
     


 
    

  
  






   
 



  

 
Template Sequence  VKQ. . PVVELDGDEMTRIIWDKIKKKLILPY. . . . LDVDLKYYDLSVESRDATSDKITQDAAEAIKKYGVGIKCATITPD
Template Known Secondary structure 
SS..


TTTTT....


STTTS






Template Predicted Secondary structure 


..






....



















Template SS confidence 















































































   7.. 10.........20.........30..... ....40.........50.........60.........70.........80
 
   81... .....90.........100.........110.........120.........130.........140.........150.......
Predicted Secondary structure 



..
















































.
Query SS confidence 



. .








































































.
Query Sequence  WEHL. . PPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQ.
Query Conservation      ..        
    

  








    

     
         

 








 
 
          .
Alig confidence 



..



























.








......




























.
Template Conservation                
 
  


 




  


 .   

    ......    










 
 
 
      
  
Template Sequence  EARVKEFNLHKMWKSPNGTIRNILGGTVFREPIV. IPRIPRLVP. . . . . . RWEKPIIIGRHAHGDQYKATDTLIPGPGSL
Template Known Secondary structure  TT
SS




S

.
TTS

SST......T

S

SSGGGS

SS
Template Predicted Secondary structure 



















.







......






















Template SS confidence 















































































   81........90.........100.........110.... .....120... ......130.........140.........150...
 
   158.160.........170.........180.........190.........200 .........210...
Predicted Secondary structure  .......................





.
Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . .










































.












Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . YEKAFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQ. SSILWREIVNEIA
Query Conservation  ....................... 
 
      

   


 
 

  
    
 

 
 




 .  


     


Alig confidence  .......................










































.












Template Conservation         
                         
    




 

  
      

 
 
 

 
  

 
     

 
Template Sequence  ELVYKPSDPTTAQPQTLKVYDYKGSGVAMAMYNTDESIEGFAHSSFKLAIDKKLNLFLSTKNTILKKYDGRFKDIFQEVY
Template Known Secondary structure 

S
TTTS

SS




TT

TTTSTT
Template Predicted Secondary structure 



























Template SS confidence 















































































   154.....160.........170.........180.........190.........200.........210.........220.........230...
 
   214 .....220.........230.........240.........250.........260.........270...... ...280.....
Predicted Secondary structure  .......




























.




Query SS confidence 
. . . . . . .





























































.








Query Sequence  T. . . . . . . EYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQG. FGLYEPAGG
Query Conservation   .......


 
      

     

  
  





 

 








 
 




 





   . 
 


 

Alig confidence 
.......

























.


































.








Template Conservation    

        
      

     

  
  
.


  

 





  
 
 



  

 


       

  

Template Sequence  EAQYKSKFEQLGIHYEHRLIDDMVAQMIKSKGGF. IMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKTFESEAAHG
Template Known Secondary structure  TT

S


.
T
TTS
TTS


S
Template Predicted Secondary structure 












.

























Template SS confidence 















































































   234.....240.........250.........260....... ..270.........280.........290.........300.........310..
 
   286...290...... ...300.........310....... ..320.........330 .........340... ..
Predicted Secondary structure 










......



........











......

Query SS confidence 










. . . . . .




















. . . . . . .












.












. . . . . .

Query Sequence  SAPDIAGKNIA. . . . . . NPIAQILSLALLLRYSLDADD. . . . . . . AACAIERAINRAL. EEGIRTGDLARGA. . . . . . AA
Query Conservation 







  
......

 
 


 



    
   ....... 
  
  

   
.  
  
 



  ......  
Alig confidence 










......














.




.......












.












......

Template Conservation 



 

  


     

 
 


 
 

 
.

       
   
  
  

  

   
  
 



          
Template Sequence  TVTRHYRKYQKGEETSTNSIASIFAWSRGLLK. RGELDNTPALCKFANILESATLNTVQQDGIMTKDLALACGNNERSAY
Template Known Secondary structure 

TTT






.T
TS



T


GGG
Template Predicted Secondary structure 












.

























Template SS confidence 















































































   313......320.........330.........340.... .....350.........360.........370.........380.........390.
 
   346...350.........360...
Predicted Secondary structure 



Query SS confidence 

















Query Sequence  VSTDEMGDIIARYVAEGV
Query Conservation    
 
  


   
 
  
Alig confidence 

















Template Conservation   

 

 


   
   
Template Sequence  VTTEEFLDAVEKRLQKEI
Template Known Secondary structure 

Template Predicted Secondary structure 

Template SS confidence 

















   392.......400.........
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions