Job Description P30125 Confidence 100.00% Date Thu Jan 5 11:45:46 GMT 2012 Rank 28 Aligned Residues 347 % Identity 28% Template c2iv0A_ PDB info PDB header:oxidoreductase Chain: A: PDB Molecule:isocitrate dehydrogenase; PDBTitle: thermal stability of isocitrate dehydrogenase from2 archaeoglobus fulgidus studied by crystal structure3 analysis and engineering of chimers Resolution 2.5 Å

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		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80
Predicted Secondary structure
Query SS confidence
Query Sequence		M	S	K	N	Y	H	I	A	V	L	P	G	D	G	I	G	P	E	V	M	T	Q	A	L	K	V	L	D	A	V	R	N	R	F	A	M	R	I	T	T	S	H	Y	D	V	G	G	A	A	I	D	N	H	G	Q	P	L	P	P	A	T	V	E	G	C	E	Q	A	D	A	V	L	F	G	S	V	G	G	P	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	P	D	N	P	I	I	P	Y	F	E	G	D	G	I	G	K	D	V	V	P	A	A	I	R	V	L	D	A	A	A	D	K	I	G	K	E	V	V	W	F	Q	V	Y	A	G	E	D	A	Y	K	L	Y	G	N	Y	L	P	D	D	T	L	N	A	I	K	E	F	R	V	A	L	K	G	P	L	T	T	P	V
Template Known Secondary structure				S	S	B								S	T	T																				T											S								S		S	S																							S
Template Predicted Secondary structure
Template SS confidence
		24	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.
		81	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.
Predicted Secondary structure																																																																													.	.	.	.	.
Query SS confidence																																																																													.	.	.	.	.
Query Sequence		W	E	H	L	P	P	D	Q	Q	P	E	R	G	A	L	L	P	L	R	K	H	F	K	L	F	S	N	L	R	P	A	K	L	Y	Q	G	L	E	A	F	C	P	L	R	A	D	I	A	A	N	G	F	D	I	L	C	V	R	E	L	T	G	G	I	Y	F	G	Q	P	K	G	R	E	G	S	.	.	.	.	.
Query Conservation																																																																													.	.	.	.	.
Alig confidence						.	.	.	.	.	.	.																																.	.	.	.	.																													.	.	.	.	.
Template Conservation						.	.	.	.	.	.	.																																.	.	.	.	.
Template Sequence		G	G	G	Y	.	.	.	.	.	.	.	R	S	L	N	V	T	I	R	Q	V	L	D	L	Y	A	N	V	R	P	V	Y	Y	L	K	G	V	P	S	P	I	K	.	.	.	.	.	H	P	E	K	V	N	F	V	I	F	R	E	N	T	E	D	V	Y	A	G	I	E	W	P	R	G	S	E	E	A	L	K	L
Template Known Secondary structure		S	S	S	S	.	.	.	.	.	.	.	S										T	T												T	T	S			S	S	S	.	.	.	.	.		G	G	G										S	S	S	G	G	G						T	T
Template Predicted Secondary structure						.	.	.	.	.	.	.																																.	.	.	.	.
Template SS confidence
		104	.	.	.								.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.						.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.
													156	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.		.	.	.	190	.	.	.	.	.	.	.	.	.	200		.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.																																.															.																	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.																																.															.																	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	G	Q	Y	E	K	A	F	D	T	E	V	Y	H	R	F	E	I	E	R	I	A	R	I	A	F	E	S	A	R	K	R	.	R	H	K	V	T	S	I	D	K	A	N	V	L	Q	.	S	S	I	L	W	R	E	I	V	N	E	I	A	T	E	Y	.	.	.	.	.	.
Query Conservation		.	.	.	.	.	.	.	.	.	.	.																																.															.																	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.																																.															.																	.	.	.	.	.	.
Template Conservation
Template Sequence		I	R	F	L	K	N	E	F	G	V	T	I	R	E	D	S	G	I	G	I	K	P	I	S	E	F	A	T	K	R	L	V	R	M	A	I	R	Y	A	I	E	N	N	R	K	S	V	T	L	V	H	K	G	N	I	M	K	Y	T	E	G	A	F	R	D	W	G	Y	E	V	A	K	Q	E	F	G	E	Y	C	I
Template Known Secondary structure															T	T																											T	T		S								T	T	T		T	T	T																S	T	T	T
Template Predicted Secondary structure
Template SS confidence
		172	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.
																	217	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	P	D	V	E	L	A	H	M	Y	I	D	N	A	T	M	Q	L	I	K	D	P	S	Q	F	D	V	L	L	C	S	N	L	F	G	D	I	L	S	D	E	C	A	M	I	T	G	S	M	G	M	L	P	S	A	S	L	N	E	Q	G	F	G	L	Y	E
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																																												.
Template Conservation																																																																												.
Template Sequence		T	E	D	E	L	W	D	K	Y	G	G	K	Q	P	E	G	K	I	V	V	K	D	R	I	A	D	N	M	F	Q	Q	I	L	T	R	T	D	E	Y	D	V	I	A	L	P	N	L	N	G	D	Y	L	S	D	A	A	A	A	L	I	G	G	L	G	I	A	P	G	S	N	I	G	D	G	.	I	G	V	F	E
Template Known Secondary structure											T	T				T	T									G	G	G								S	G	G	G																						T	T		G	G	G								T	T	.
Template Predicted Secondary structure																																																																												.
Template SS confidence
		252	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.		.	.	.	.	330
		282	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.			.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																															.	.
Query SS confidence																																																															.	.
Query Sequence		P	A	G	G	S	A	P	D	I	A	G	K	N	I	A	N	P	I	A	Q	I	L	S	L	A	L	L	L	R	Y	S	L	D	A	D	D	A	A	C	A	I	E	R	A	I	N	R	A	L	E	E	G	I	R	T	G	D	L	A	R	G	.	.	A	A	A	V	S	T	D	E	M	G	D	I	I	A	R	Y	V
Query Conservation																																																															.	.
Alig confidence																																.																															.	.
Template Conservation																																.
Template Sequence		P	V	H	G	S	A	P	K	Y	A	G	Q	N	K	V	N	P	T	A	E	I	L	T	G	A	L	M	F	E	Y	.	I	G	W	K	D	A	S	E	M	I	K	K	A	V	E	M	T	I	S	S	G	I	V	T	Y	D	I	H	R	H	M	G	G	T	K	V	G	T	R	E	F	A	E	A	V	V	E	N	L
Template Known Secondary structure			S	S				S	T	T	T	T	S	S		S																.	T	T																		T	T												S
Template Predicted Secondary structure																																.
Template SS confidence
		331	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.
		360	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Q	S
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		410	.

No model constructed - rank, confidence too low

---

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions