|   |
13 | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | |
|
. | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
Query Sequence |   |
V | A | L | G | G | G | H | G | L | G | R | V | L | S | S | L | S | S | . |
. |
L | G | S | R | L | T | G | I | V | T | T | T | D | N | G | G | S | T | G | R | I | R | R | S | E | G | G | I | A | W | G | D | M | R | N | C | L | N | Q | L | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | E | P | S | V | A |
Query Conservation |   |
|   |
|   |
|
|
|
|   |   |   |
|
|   |
|
|   |   | . | . |   |   |   |   |   |
|   |
|
|
|
|   |
|
|
|
|
|
|
|   |
|
|   |   |   |
|   |   |   |   |
|
|
|
|   |   |
|   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|
|
|
|
|   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|   |
|   | . | . | . | . | . | . | . |   |
|
|
|
|   |   |
|   |
|
|
|   |   |   |
|   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |
Template Sequence |   |
I | I | F | S | G | G | T | G | T | P | K | L | L | D | G | L | K | E | I | L | P | E | E | E | L | T | V | V | V | N | T | A | E | D | L | W | V | S | G | N | L | I | . |
. |
. |
. |
. |
. |
. |
S | P | D | L | D | T | V | L | Y | L | F | S | D | Q | I | D | R | K | R | W | W | G | I | E | N | D | T | F | G | T | Y |
Template Known Secondary structure |   |
 |  |  |  |
| T | T | T |  |  |  |  |  |  |  |  | T | T | T | S |
| G | G | G |
|  |  |  |  |
|
| T | T |
|  |  |  | T | T |  |  |  | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  | T | T | T |
| B |
| T | T | T | T | S | S | B | T | T |
|
|
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . |
  |
  |   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | |
. | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | A | M | F | E | Y | R | F | G | G | N | G | E | L | S | G | H | N | L | . |
G | N | L | M | L | K | A | L | D | H | L | S | V | R | P | L | E | A | I | N | L | I | R | N | L | L | K | V | D | T | H | L | I | P | M | S | E | H | P | V | D | L | M | A | I | D | D | Q | G | H | E | V | Y | G | E | V | N | I | D | Q |
Query Conservation |   |
  |   |
|   |   |   |
|
|   |   |   |   |   |
|   |
|
|   |
| . |
|
|
|   |
|   |
|   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |
|   |
|   |
|   |
|
|
|   |
|   |   |   |
|   |
|   |
|   |   |   |
|
|   |   |
|   |
|
|   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |
|   |
|   |
|   |
|
|
|   |
|   |   |   |
|   |
|   |
|   |   |   |
|
|   |   |   |   |
|
|   |   |
|   |   |
Template Sequence |   |
E | R | X | K | E | L | G | I | E | E | G | L | K | L | G | D | R | D | R | A | T | H | I | I | R | S | N | I | I | R | D | G | A | S | L | T | D | S | T | V | K | L | S | S | L | F | G | I | K | A | N | I | L | P | X | S | D | D | P | V | S | T | Y | I | E | T | A | E | G | I | X | H | F | Q | D | F | W | I | G | K |
Template Known Secondary structure |   |
 |  |  |  |  |  | T |
|
|
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| S |  |  |  |  | S | B | S | S |
|
|  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T | T | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
75 | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . |
  |
  |   |
157 | . | . | |
160 | . | . | . | . | . | . | . | . | |
|
. | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . |
Predicted Secondary structure |   |
|
|
| . |
|  |  |  |  |  |  |
|
| . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | T | T | . |
P | I | Q | E | L | L | L | T | P | . |
. |
N | V | P | A | T | R | E | A | V | H | A | I | N | E | A | D | L | I | I | I | G | P | G | S | F | Y | T | S | L | M | P | I | L | L | L | K | E | I | A | Q | A | L | R | R | T | P | A | P | M | V | Y | I | G | N | L | G | R | E | L | S | L | P | A | A | N |
Query Conservation |   |
  |   |   | . |   |
|   |
|
|   |
|   |   | . | . |   |   |   |   |   |
|   |   |
|   |
|
|   |   |
|
|   |
|
|   |
|
|
|
|   |   |
|
|
|   |
|   |
|
|
|   |
|
|   |   |
|
|   |   |
|   |
|   |
|
|   |
|   |
|
|   |   |   |   |
|   |
|
|   |
|
Alig confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |   |
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|
|   |   |   | . | . |   |   |
|   |
|   |
|
|   |   |   |   |   | . |   |   |
|   |
Template Sequence |   |
R | G | E | P | D | V | R | G | V | D | I | R | G | V | S | E | A | S | I | S | P | K | V | L | E | A | F | E | K | E | E | N | I | L | I | G | P | S | N | P | I | T | S | I | G | P | I | I | S | L | P | G | X | R | E | L | L | K | K | K | . |
. |
K | V | V | A | V | S | P | I | I | G | N | A | P | . |
V | S | G | P |
Template Known Secondary structure |   |
T | T |
| S |
|
| S |  |  |  |  |  | T | T | T | T |
|
| B |
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
| S | S |
| T | T | T | T |  |  |  |  |  |  | S | T | T |  |  |  |  |  | T | T | S | . | . |  |  |  |  |  |
| S |
|
| S | S | S |
| . |
|
| S | T |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |
|
|
|
|
|
|
|
| . |
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
155 | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | |
|
. | . | . | . | . | 220 | . | . | . | . | . | . | . | |
. | . | 230 | . |
  |
  |   |
234 | . | . | |
|
|
|
|
|
|
. | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . |
Predicted Secondary structure |   |
|
|  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
| . | . | . | . | . |
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | K | L | . |
. |
. |
. |
. |
. |
. |
E | S | K | L | A | I | M | E | Q | Y | V | G | K | K | V | I | D | A | V | I | V | G | P | K | V | D | . |
. |
. |
. |
. |
V | S | A | V | K | E | R | I | V | I | Q | E | V | L | E | A | S | D | I | P | Y | R | H | D | R | Q | L | L | H | N | A | L | E | K | A | L | Q | A | L |
Query Conservation |   |
  |   |   | . | . | . | . | . | . | . |   |
|   |
|   |   |
|   |   |   |   |
|   |   |   |   |
|   |
|
|
|   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|
|
|   |   |   |
|
|   |   |
|   |   |
|   |   |   |
|
Alig confidence |   |
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   | . |   |   |   |
|   |   |
|
|
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   | . | . | . | . |   |   |
|   |   |   |
|
|
|   |
|
|   |   |   |   |   |   |
Template Sequence |   |
A | G | K | L | X | P | A | C | G | I | E | V | S | S | X | G | V | A | E | Y | Y | Q | . |
D | F | L | D | V | F | V | F | D | E | R | D | R | A | D | E | F | A | F | E | R | L | G | C | H | A | S | R | A | D | T | L | X | T | S | . |
. |
. |
. |
T | E | K | S | K | E | L | A | E | I | V | V | Q | A | F | L | E | H |
Template Known Secondary structure |   |
T | T | T | T | S | T | T | T | T |
|
| S | S |  |  |  |  |  |  | T | T | T | . | T | T |
|
|  |  |  |  |
| S | S |
|
|
|
|  |  |  |  |  | T | T |
|
|  |  |  |  |
|
|
|
|
|
| S | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
| . |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
| . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
232 | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | |
. | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | |
|
|
|
. | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . |
  |