|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | F | A | L | C | D | V | N | A | F | Y | A | S | C | E | T | V | F | R | P | D | L | W | G | K | P | V | V | V | L | S | N | N | D | G | C | V | I | A | R | N | A | E | A | K | A | L | G | V | K | M | G | D | P | W | F | K | Q | K | D | L | F | R | R | C | G | V | V | C | F | S | S | N | Y | E | L | Y | A | D | M |
Query Conservation |   |
|
|   |
|
|
|   |
|   |
|
|
|
|
|
|   |   |   |   |
|   |
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|
|   |
|   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|
|   |
|   |
|
|
|
|
|
|   |   |   |   |
|   |
|   |   |   |
|
|
|
|   |   | . | . |   |   |   |
|   |
|   |
|
|   |
|
|   |   |
|
|
|   |
|
|
|   |   |   |
|   |   |
|
|
|   | . | . |
|   |
|
|   |   |
|   |   |   |
|   |   |   |
Template Sequence |   |
T | I | V | H | I | D | M | D | A | F | Y | A | A | V | E | M | R | D | N | P | E | L | K | D | K | P | I | A | V | G | S | . |
. |
M | S | M | L | S | T | S | N | Y | H | A | R | R | F | G | V | R | A | A | M | P | G | F | I | A | K | R | L | C | P | Q | . |
. |
L | I | I | V | P | P | N | F | D | K | Y | R | A | V |
Template Known Secondary structure |   |
|  |  |  |  |  |  | T | T |  |  |  |  |  | T | T | T | S |
| G | G | G | S | S | S |
|  |  |  |  |
| . | . | S | S |
|  |  |  |  |
| S | S | T | T | T | T | T |
|
| T | T |
|
|  |  |  |  |  | T | T |
| T | T | . | . |
|  |  |  |
|
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
| . | . |
|
|  |  |  |  |  |
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
| . | . |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
102 | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | |
|
. | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | |
|
. | . | . | . | . | . | 170 | . | . | . | . | . | . | . |
  |
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | N | R | V | M | S | T | L | E | E | L | S | P | R | V | E | I | Y | S | I | D | E | A | F | C | D | L | T | G | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | N | C | R | D | L | T | D | F | G | R | E | I | R | A | T | V | L | Q | R | T | H | L | T | V | G | V | G | I | A |
Query Conservation |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|
|
|   |   |
|
|
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |
|
|   |   |
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |
|
|   |   |   |   |
|   |
|
|   |   |
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |   |   |
|
|
|
|   |
|
|
|
|
|
Template Sequence |   |
S | K | E | V | K | E | I | L | A | D | Y | D | P | N | F | M | A | M | S | L | D | E | A | Y | L | N | I | T | K | H | L | E | E | R | Q | N | W | P | E | D | K | R | R | Y | F | I | K | N | S | V | V | F | G | T | S | A | Q | E | V | V | K | E | I | R | F | R | I | E | Q | K | T | T | L | T | A | S | A | G | I | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
| T | T |
|
| B |
| S | S | S |  |  |  |  |
| T |  |  |  |  |  |  |  | T | S |
|
| T | T | T | S | B |
|
|
|
|
|
|
| B |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
178 | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . |
  |
  |   |
141 | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | T | K | T | L | A | K | L | A | N | H | A | A | K | K | W | Q | R | Q | T | G | G | V | V | D | L | S | N | L | E | R | Q | R | K | L | M | S | A | L | P | V | D | D | V | W | G | I | G | R | R | I | S | K | K | L | D | A | M | G | I | K | T | V | L | D | L | A | D | T | D | I | R | F | I | R | K | H | F | N | V |
Query Conservation |   |
  |
|   |   |
|
|
|
|
|
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|   |
|
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|
|
|   |   |
|
|   |   |   |
|   |   |
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |
|
|
|
|
|
|   |   |   |
|
|
|
|
|   | . | . | . | . |   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |
|   |
|
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|
|
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
Template Sequence |   |
P | N | T | M | L | A | K | V | C | S | D | K | N | K | P | N | G | Q | Y | . |
. |
. |
. |
Q | I | L | P | N | R | Q | A | V | M | D | F | I | K | D | L | P | I | R | K | V | S | G | I | G | K | V | T | E | K | M | L | K | A | L | G | I | I | T | C | T | E | L | Y | Q | Q | R | A | L | L | S | L | L | F | S | E | T |
Template Known Secondary structure |   |
S | S |  |  |  |  |  |  |  |  | T | T | T |
| S | S |
|  |  | . | . | . | . |  |
|
| S | S |  |  |  |  |  |  |  |  | T | T |
| B | S | T | T | S | T | T |
|
|  |  |  |  |  |  |  |  |  | T | T |
|
| B |  |  |  |  |  |  | T |  |  |  |  |  |  |  | S |
|  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  | . | . | . | . |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
315 | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | |
|
|
|
. | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 |
  |
  |   |
221 | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | E | R | T | V | R | E | L | R | G | E | P | C | L | Q | L | E | E | F | A | P | T | K | Q | E | I | I | C | S | R | S | F | G | E | R | I | T | D | Y | P | S | M | R | Q | A | I | C | S | Y | A | A | R | A | A | E | K | L | R | S | E | H | Q | Y | C | R | F | I | S | T | F | I | K | T | S | P | F | A | L | N |
Query Conservation |   |
  |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |   |
|   |   |   |
|   |
|
|
|   |   |   |
|   |   | . |   |   |   |   |
|
|
|
|   |
|   |
|
|   | . |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |   |   |   | . | . |
Template Sequence |   |
S | W | H | Y | F | L | H | I | S | L | G | L | G | S | T | H | L | T | R | . |
D | G | E | R | K | S | M | S | V | E | R | T | F | S | . |
E | I | N | K | A | E | E | Q | Y | S | L | C | Q | E | L | C | S | E | L | A | Q | D | L | Q | K | E | R | L | K | G | R | T | V | T | I | K | L | K | N | V | N | F | E | . |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T |
|
|
|
| S |
|
|
| . |
|
|
|
|
|  |  |  |  |  |  |  |  |  | . |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  | T | T |
|
| . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |
|
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
391 | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | |
410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | |
. | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | |
|
  |
  |   |
301 | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | |
|
|
|
340 | . | . | . | . | . | . | . | . | . | 350 |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | P | Y | Y | G | N | S | A | S | V | K | L | L | T | P | T | Q | D | S | R | D | I | I | N | A | A | T | R | S | L | D | A | I | W | Q | A | G | H | R | . |
. |
. |
. |
Y | Q | K | A | G | V | M | L | G | D | F |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . |
|
|   |
|   |
|   |   |   |   |
|
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . |   |   |
|
|
|   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|   |
|
Template Sequence |   |
. |
. |
. |
. |
V | K | T | R | A | S | T | V | S | S | V | V | S | T | A | E | E | I | F | A | I | A | K | E | L | L | K | T | E | I | D | A | D | F | P | H | P | L | R | L | R | L | M | G | V | R | I | S | S | F |
Template Known Secondary structure |   |
. | . | . | . |  |  |
|
|  |  |  |  |  |  |  |  |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T | S |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
. | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
467 | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . |
  |