|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | F | A | L | C | D | V | N | A | F | Y | A | S | C | E | T | V | F | R | P | D | L | W | G | K | P | V | V | V | L | S | N | N | D | G | C | V | I | A | R | N | A | E | A | K | A | L | G | V | K | M | G | D | P | W | F | K | Q | K | D | L | F | R | R | C | G | V | V | C | F | S | S | N | Y | E | L | Y | A | D | M |
Query Conservation |   |
|
|   |
|
|
|   |
|   |
|
|
|
|
|
|   |   |   |   |
|   |
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|
|   |
|   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|
|   |
|   |
|
|
|
|
|
|   |   |   |   |
|   |
|   |   |   |
|   |   |
|   | . | . | . | . | . | . |
|   |
|   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |   |   |
|   |   |
|
|
|   | . | . |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
I | V | I | F | V | D | F | D | Y | F | F | A | Q | V | E | E | V | L | N | P | Q | Y | K | G | K | P | L | V | V | S | . |
. |
. |
. |
. |
. |
V | Y | S | A | N | Y | E | A | R | K | L | G | V | K | A | G | M | P | I | I | K | A | M | Q | I | A | P | S | . |
. |
A | I | Y | V | P | M | R | K | P | I | Y | E | A | F |
Template Known Secondary structure |   |
|  |  |  |  |  | B | T | T |  |  |  |  |  |  |  |  |  | S |
| S |
| S | S | S |
| B |
|
|
| . | . | . | . | . | . |
|
|
|
|
|  |  |  |  | T | T | T |
|
| S | S | S |
|  |  |  |  | T | T | S | S | T | T | . | . | S | B |
|
|
|
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
| . | . |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | |
|
60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . |
  |
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | |
|
. | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | N | R | V | M | S | T | L | E | E | L | S | P | R | V | E | I | Y | S | I | D | E | A | F | C | D | L | T | G | V | R | N | C | R | . |
. |
D | L | T | D | F | G | R | E | I | R | A | T | V | L | Q | R | T | H | L | T | V | G | V | G | I | A | Q | T | K | T | L | A | K | L | A | N | H | A | A | K | K | W | Q | R |
Query Conservation |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   | . | . |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |
|
|   |   |
|
|
|
|
|   |
|   |   |
|
|
|
|
|
|   |   |   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|
|
|
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |   |
|   |
|
|
|   |   |   |   |
|
|
|
|
|
|   |   |   |
|
|   |
| . |
Template Sequence |   |
S | N | R | I | M | N | L | L | N | K | H | A | D | K | I | E | V | A | S | I | D | E | A | Y | L | D | V | T | N | K | V | E | G | N | F | E | N | G | I | E | L | A | R | K | I | K | Q | E | I | L | E | K | E | K | I | T | V | T | V | G | V | A | P | N | K | I | L | A | K | I | I | A | D | K | S | K | P | N | G | . |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |
| S | T | T |  |  |  |  |  |
| T | T | T | T | T | T |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| B |
|  |  |  |  | S | S |  |  |  |  |  |  |  |  |  | T | T | T | T | T |
| . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | |
  |
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | |
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | T | G | G | V | V | D | L | S | N | L | E | R | Q | R | K | L | M | S | A | L | P | V | D | D | V | W | G | I | G | R | R | I | S | K | K | L | D | A | M | G | I | K | T | V | L | D | L | A | D | T | D | I | R | F | I | R | K | H | F | N | . |
V | V | L | E | R | T | V | R | E | L | R | G | E | P | C | L | Q | L |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|   |
|
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|
|
|   |   |
|
|   |   |   |
|   |   |
|
|
| . |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |
|
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|   |
|
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |
|   |
|   |   |   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
L | G | V | I | R | P | T | E | V | Q | D | F | L | N | E | L | D | I | D | E | I | P | G | I | G | S | V | L | A | R | R | L | N | E | L | G | I | Q | K | L | R | D | I | L | S | K | N | Y | N | E | L | E | K | I | T | G | K | A | K | A | L | Y | L | L | K | L | A | Q | N | K | Y | S | E | P | V |
Template Known Secondary structure |   |
. | . | . | . | . |  |  |  |
|
| G | G | G |  |  |  |  |  |  | T |
| B | S | T | T |
| T | T | S |
|  |  |  |  |  |  |  | T | T | T | T |
|
| B | G | G | G | G | G | G | S |
|  |  |  |  |  | T | T | S |
| S |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|
|
Template Predicted Secondary structure |   |
. | . | . | . | . |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
164 | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
  |
  |   |
238 | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | E | F | A | P | T | K | Q | E | I | I | C | S | R | S | F | G | E | R | I | T | D | Y | P | S | M | R | Q | A | I | C | S | Y | A | A | R | A | A | E | K | L | R | S | E | H | Q | Y | C | R | F | I | S | T | F | I | K | T | S | P | F | A | L | N | E | P | Y | Y | G | N | S | A | S | V | K | L | L | T | P | T | Q |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
Alig confidence |   |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   | . | . |   |   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   | . | . | . | . | . | . |   |   |
|   |   |   |   |
|   |   |   |   |   |
Template Sequence |   |
E | N | K | . |
. |
S | K | I | P | H | G | R | Y | L | T | L | P | Y | N | T | R | D | V | K | V | I | . |
. |
. |
L | P | Y | L | K | K | A | I | N | E | A | Y | N | K | V | N | G | I | P | M | R | I | T | V | I | A | I | M | E | D | L | D | . |
. |
. |
. |
. |
. |
I | L | S | K | G | K | K | F | K | H | G | I | S |
Template Known Secondary structure |   |
| S |  | . | . |  |
|
|
|  |  |  |  |  |
|
| S | S |
| B |
|
| S | T | T | T | . | . | . | T |  |  |  |  |  |  |  |  |  |  |  |  | T | S | S | S |
|  |  |  |  |  |  |  |  |  |  | S | S | S |
| . | . | . | . | . | . |  |  |  |  |  |  |  |
| S | S |
|
|
|
Template Predicted Secondary structure |   |
|
|
| . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
239 | 240 | . | |
|
. | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | |
|
|
. | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | |
|
|
|
|
|
. | . | . | . | . | 300 | . | . | . | . | . | . | . |
  |
  |   |
318 | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | |
|
. | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | S | R | D | I | I | N | A | A | T | R | S | L | D | A | I | W | . |
. |
Q | A | G | H | R | Y | Q | K | A | G | V | M | L | G | D | F | F | S |
Query Conservation |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   | . | . |   |   |   |   |   |
|
|   |
|   |
|   |   |   |   |
|   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |
|
|   |
Template Sequence |   |
. |
I | D | N | A | Y | K | V | A | E | D | L | L | R | E | L | L | V | R | D | K | R | R | N | V | R | R | I | G | V | K | L | D | N | I | I | I |
Template Known Secondary structure |   |
. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
308 | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . |
  |