|   |
6 | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | |
. | . | . | . | . | . | . | 80 | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | A | D | E | I | R | E | Q | F | S | Q | A | M | S | A | M | Y | Q | Q | E | V | P | Q | Y | G | T | L | L | E | L | V | A | D | V | N | L | A | V | L | E | N | N | P | Q | L | H | E | K | M | V | N | A | D | E | L | A | R | L | N | V | E | R | H | G | A | I | R | . |
V | G | T | A | Q | E | L | A | T | L | R | R |
Query Conservation |   |
  |   |   |
|
|
|
|   |
|
|   |
|
|
|   |
|
|   |   |
|
|
|
|
|
|   |
|
|   |   |
|   |   |
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |
|
|
|
|
|
|
| . |
|
|
|   |   |
|
|   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   | . | . | . | . | . | . |
|   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
| . |   |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |
|
|
Template Sequence |   |
E | G | R | A | T | R | A | E | I | A | Q | A | L | N | X | V | . |
. |
. |
. |
. |
. |
L | F | A | G | I | L | D | R | V | P | T | G | R | A | Y | T | D | D | V | A | A | T | G | . |
G | V | V | F | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
H | G | A | L | R | T | V | W | R | D | N | G | A | L | P | E | G | E |
Template Known Secondary structure |   |
T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | . |
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
| T | T | S |
| S | T | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |
| . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
36 | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | |
. | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . |
  |
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | F | A | I | M | G | M | Y | P | V | S | Y | Y | D | L | S | Q | A | G | V | P | V | H | S | T | A | F | R | P | I | D | D | A | S | L | A | R | N | P | F | R | V | F | T | S | L | L | R | L | E | L | I | E | N | E | I | L | R | Q | K | A | A | E | I | L | R | Q | R | D | I | F | T | P | R | C | R | Q | L | L | E |
Query Conservation |   |
  |
|
|   |   |
|
|   |
|
|
|
|
|
|
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |
|
|
|   |
|   |
|
|   |   |
|   |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |
|
|   |
|
|
|   |   |   |
|   |
|   |
|
|   |
|
|
|   |
|
|   |
|   |
|   |
|   |
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|   |
|
|   |
|   |
|
|
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
Template Sequence |   |
A | A | F | T | R | I | L | R | P | L | G | Y | R | L | N | G | N | Y | P | L | D | R | I | S | X | T | G | R | S | Y | A | H | A | D | A | P | E | G | I | A | Q | F | F | V | S | E | F | H | P | E | R | F | S | D | A | F | R | E | A | V | G | R | V | T | G | N | S | A | D | P | L | T | P | R | A | Q | T | L | L | W |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  | G | G | G | T |  |  |  |  |  |  |  |  | T | T |
| T | T | T | S |
|  |  |  |  |  |  |  |
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . |
  |
  |   |
165 | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | Y | E | Q | Q | G | G | F | N | E | T | Q | A | Q | E | F | V | Q | E | A | L | E | T | F | R | W | H | Q | S | A | T | V | D | E | E | T | Y | R | A | L | H | N | E | H | R | L | I | A | D | V | V | C | F | P | G | C | H | I | N | H | L | T | P | R | T | L | D | I | D | R | V | Q | S | M | M | P | E | C | G | I |
Query Conservation |   |
  |   |
|   |   |
|
|
|   |   |   |   |
|   |
|
|
|   |   |
|   |   |   |
|   |
|
|   |   |
|   |
|   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |
|
|
|   |   |
|   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |   |
|   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
| . |   |   |   |   |   |   |
|   |   |
|
|
|
|   |
|   |   |
|
|
|
|
|
|
|
|   |   |   | . |
|   |   |   |
|
|
|
|   |   |
|
|
|
|   |   |   |   |
| . |   |   |   |   |   |   |
Template Sequence |   |
Q | L | D | R | D | G | V | L | T | V | A | D | G | A | E | L | I | G | L | L | V | P | C | F | . |
E | R | Q | H | G | V | P | R | L | A | D | Y | E | T | L | L | R | E | S | A | E | X | A | W | I | A | T | E | . |
G | N | A | F | N | H | A | T | D | R | V | D | D | V | F | G | L | S | E | . |
Q | Q | A | L | G | R |
Template Known Secondary structure |   |
 |  |  |  |  | S |  |  |
|  |  |  |  |  |  |  |  |  |  |  | G | G | G | S | . | S |
|
| S |
|
|
| B |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  | . | T | T | S |
| S |  |  |  |  |  |
| S |
|  |  |  |  |  |  | . |  |
|
|
| S |
|
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | |
. | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | |
. | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | |
. | . | . | . | . | . |
  |
  |   |
245 | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | |
. | . | |
|
|
. | . | . | . | . | . | 290 | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
| . |
|  | . | . | . |  |  |  |  |  |
|  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | P | K | I | L | I | E | G | P | P | R | R | E | V | P | I | L | L | R | Q | T | S | F | K | A | L | E | E | T | V | L | F | A | G | Q | K | Q | . |
G | T | . |
. |
. |
H | T | A | R | F | G | E | I | E | Q | R |
Query Conservation |   |
  |   |
|
|   |
|
|
|
|
|   |
|   |   |   |
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|   |
|   |   |   |   |   | . |
|   | . | . | . |
|   |
|
|
|
|
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|
|   |
|   |   |   | . | . | . | . | . | . | . |   |
|   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |
|
|
|
|
|
|
|
Template Sequence |   |
P | X | D | V | E | V | S | G | S | G | R | . |
. |
. |
. |
. |
. |
. |
V | Q | T | A | F | R | A | D | T | V | R | R | Q | F | I | G | A | Q | G | E | T | V | E | R | D | V | P | G | S | F | Y | E | F | I | T | R |
Template Known Secondary structure |   |
|
|
|
|
|
|
| T | T | S |
| . | . | . | . | . | . | . |
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
258 | . | 260 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . |
  |