|   |
35 | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | |
|
. | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | I | S | Q | E | G | R | V | I | D | P | S | D | A | R | K | I | T | T | S | E | G | Q | S | Y | G | M | F | . |
. |
S | A | L | A | A | N | D | R | A | A | F | D | N | I | L | D | W | T | Q | N | N | L | A | Q | G | S | L | K | E | R | L | P | A | W | L | W | G | K | K | E | N | S | K | W | E | V | L | D | S | N |
Query Conservation |   |
  |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
| . | . |   |
|
|   |   |   |
|   |   |   |
|
|   |
|
|   |
|
|
|   |   |
|   |   |   |
|   |   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
| . | . |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   | . |   |
|
| . | . |   |
|
|   |   |
|   |
|
|   |   |
|
|   |
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
Template Sequence |   |
V | S | D | G | S | N | K | Y | V | L | N | D | N | T | . |
D | W | T | . |
. |
D | G | F | W | S | G | I | L | W | L | C | Y | E | Y | T | G | D | E | Q | Y | R | E | G | A | V | R | T | V | A | S | F | R | E | R | L | D | R | F | E | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L |
Template Known Secondary structure |   |
 |  | S | S | S | S | S |  |  |  |  | S | S |
| . | S | S |
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |
|
|
|
| . |
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
27 | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | |
. | . | . | |
|
. | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. |
  |
  |   |
113 | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|  |  |  |
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | A | S | D | G | D | V | W | M | A | W | S | L | L | E | A | G | R | L | W | K | E | Q | R | Y | T | D | I | G | S | A | L | L | K | R | I | A | R | E | E | V | V | T | V | P | G | L | G | S | M | L | L | P | G | K | V | G | F | A | E | D | N | S | W | R | F | N | P | S | Y | L | P | P | T | L | A | Q | Y | F | T |
Query Conservation |   |
  |
|
|
|
|
|
|   |
|
|   |
|
|
|   |
|   |   |   |
|
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|   |   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |
|
|   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   | . | . | . |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|   |
|
|   |   |   |   |
Template Sequence |   |
D | H | H | D | I | G | F | L | Y | S | L | S | A | K | A | Q | W | I | V | E | K | D | E | S | A | R | K | L | A | L | D | A | A | D | V | L | M | R | R | . |
. |
. |
W | R | A | D | A | G | I | I | Q | A | W | G | P | K | G | D | P | E | N | G | G | R | I | I | I | D | C | L | L | N | L | P | L | L | L | W | A | G |
Template Known Secondary structure |   |
S | S | S | T |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . | . |  |  | T | T | T | T |  |  |
|
| S | S | S | T | T |
| T | T | T | T | T |  |  |  | G | G | G | G | G | G |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | |
|
|
. | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
  |
  |   |
193 | . | . | . | . | |
|
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | |
|
. | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 250 | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | F | G | A | P | . |
. |
W | T | T | L | R | E | T | N | Q | R | L | L | L | E | T | . |
. |
A | P | K | G | F | S | P | D | W | V | R | Y | E | K | D | K | G | W | Q | L | K | A | E | K | T | L | I | S | S | Y | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | I | R | V | Y | M | W | V | G | M | M | P |
Query Conservation |   |
  |   |   |   |   | . | . |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   | . | . |   |   |
|
|
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|
|   |
|
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |   |
|
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|   |   |
|   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |
|
|
|
|
|
|
|   |   |   |
|
|   |   |   |
|   |   |
|   | . | . | . |
Template Sequence |   |
E | Q | T | G | D | P | E | Y | R | R | V | A | E | A | H | A | L | K | S | R | R | F | L | V | R | G | D | D | S | S | Y | H | T | F | Y | F | D | P | E | N | G | N | A | I | R | G | G | T | H | Q | G | N | T | D | G | S | T | W | T | R | G | Q | A | W | G | I | Y | G | F | A | L | N | S | R | Y | L | G | . |
. |
. |
Template Known Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | B |
| T | T | S |
| B |
| S |  |  |  |  |
| T | T | T |
|
|  |  |  |  |  |
| S | S | S | S | S | T | T | S |
| B |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | . |
Template Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | |
|
|
  |
  |   |
256 | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | |
|
. | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  | . | . |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | S | D | P | Q | K | A | R | M | L | N | R | F | K | P | M | A | T | F | T | E | K | N | G | Y | P | P | E | K | V | . |
. |
D | V | A | T | G | K | A | Q | G | K | G | P | V | G | F | S | A | A | M | L | P | F |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
| . | . |
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . |
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |
|   |
|
|
|
Template Sequence |   |
. |
. |
N | A | D | L | L | E | T | A | K | R | M | A | R | H | F | L | A | R | V | P | E | D | G | V | V | Y | W | D | F | E | V | P | Q | E | P | S | S | Y | R | D | S | S | A | S | A | I | T | A | C | G | L | L |
Template Known Secondary structure |   |
. | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T | S |
|
| B | S | B | T | T | S |
|
|
| T | T | S |
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
239 | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 |
  |