|   |
27 | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | |
|
|
|
. | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | W | E | Q | F | K | K | D | Y | I | S | Q | E | G | R | V | I | D | P | S | D | A | R | K | I | T | T | S | E | G | Q | S | Y | G | M | F | S | A | . |
. |
. |
. |
L | A | A | N | D | R | A | A | F | D | N | I | L | D | W | T | Q | N | N | L | A | Q | G | S | L | K | E | R | L | P | A | W | L | W | G | K | K | E |
Query Conservation |   |
  |
|   |   |   |
|   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|   |
| . | . | . | . |
|   |   |   |
|   |   |   |
|
|   |
|
|   |
|
|
|   |   |
|   |   |   |
|   |   |   |   |
|   |
|
|   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|   |   |
|   |   |   |
|   |
|   |
|
| . | . |
|   |
|
|
|   |   |   |   |
|   |   | . |
|   |   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
A | W | K | G | Y | R | K | F | A | W | G | H | D | E | . |
. |
L | K | P | V | S | R | S | F | S | E | W | F | . |
G | L | G | L | T | L | I | D | A | L | D | T | M | W | I | L | G | L | R | K | E | F | E | E | A | R | K | W | V | S | K | K | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
| T | T | S | S |  | . | . |  |  | T | T | T | T |  |  |  |
| S | S | . | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |  |  |
|
|
|
|
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | |
|
. | . | . | . | . | . | 280 | . | . | . | . | . | |
. | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
103 | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | |
|
. | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | S | K | W | E | V | L | D | S | N | S | A | S | D | G | D | V | W | M | A | W | S | L | L | E | A | G | R | L | W | K | E | Q | R | Y | T | D | I | G | S | A | L | L | K | R | I | A | R | E | E | V | V | T | V | P | G | . |
. |
L | G | S | M | L | L | P | G | K | V | G | F | A | E | D | N | S | W | R | F | N | P |
Query Conservation |   |
  |   |   |   |   |
|   |
|   |
|   |
|
|
|
|
|
|   |
|
|   |
|
|
|   |
|   |   |   |
|
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |   |   |
| . | . |   |   |   |   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |
|
|
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . |   |
|   |   |   |   |   |
|   |
|
|
|
|   |
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |
|   |   |
|
|   |
|
|   |   |
|
|
|   |
|
| . |   |
|
|   |
|
|
|
|
|
|   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
. |
. |
H | F | E | K | D | V | D | V | N | L | F | E | S | T | I | R | I | L | G | G | L | L | S | A | Y | H | L | S | G | D | S | L | F | L | R | K | A | E | D | F | G | N | R | L | M | . |
P | A | F | R | T | P | S | K | I | P | Y | S | D | V | N | I | G | T | G | V | A | H | P | P | R | W | T | S | D | S | T | V |
Template Known Secondary structure |   |
. | . |
|
|
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | . | G | G | G |
| S | T | T | S |
|
|
| S |  |  |  | T | T | T |
|
|  |  |
|
| T | T |
| S |  |  |  |  |
Template Predicted Secondary structure |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
319 | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | |
. | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . |
  |
  |   |
181 | . | |
|
. | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | |
|
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | |
|
. | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | |
|
|
250 | . |
Predicted Secondary structure |   |
 |  | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  | . | . | . |  |  |
Query SS confidence |   |
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
Query Sequence |   |
S | Y | . |
. |
L | P | P | T | L | A | Q | Y | F | T | R | F | G | A | P | . |
. |
W | T | T | L | R | E | T | N | Q | R | L | L | L | E | T | A | P | . |
. |
K | G | F | S | P | D | W | V | R | Y | E | K | D | K | G | W | Q | L | K | A | E | K | T | L | I | S | S | Y | D | A | I | R | V | Y | M | . |
. |
. |
W | V |
Query Conservation |   |
|
| . | . |   |   |
|   |   |   |   |   |
|
|   |   |   |   |   | . | . |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   | . | . |
|
|
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
| . | . | . |
|   |
Alig confidence |   |
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
Template Conservation |   |
|   |   |
|
|
|   |
|
|
|   |   |
|
|   |
|
|
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |   | . |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|
|
|
|
|   |   |
|
Template Sequence |   |
A | E | V | T | S | I | Q | L | E | F | R | E | L | S | R | L | T | G | D | K | K | F | Q | E | A | V | E | K | V | T | Q | H | I | H | G | L | S | G | K | K | D | G | L | V | P | M | F | I | N | T | H | . |
S | G | L | F | T | H | L | G | V | F | T | L | G | A | R | A | D | S | Y | Y | E | Y | L | L | K | Q | W | I |
Template Known Secondary structure |   |
 |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |
|
| B | T | T | B |
|
| S |  |  |  | T | T | . | T |
|
|  |  | S | T | T |  |  |
| S | S | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
| . |
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
396 | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | |
. | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . |
  |
  |   |
252 | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | |
|
. | . | . | . | . | . | . | 290 | . | . | . | . | |
|
|
. | . | . | . | . | 300 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | M | M | P | D | S | D | P | Q | K | A | R | M | L | N | R | F | K | P | M | A | T | F | T | E | K | N | G | Y | P | P | . |
. |
E | K | V | D | V | A | T | G | K | A | Q | G | . |
. |
. |
K | G | P | V | G | F | S | A | A | M | L | P | F |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . |   |   |
|
|   |   |
|
|   |   |   |   | . | . | . |   |   |   |   |
|   |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |   |   |
|
Template Sequence |   |
Q | G | G | K | Q | E | T | Q | L | L | E | D | Y | V | E | A | I | E | G | V | R | T | H | L | L | R | H | S | E | P | S | K | L | T | F | V | G | E | L | A | H | G | R | F | S | A | K | M | D | H | L | V | C | F | L | P | G | T | L | A | L |
Template Known Secondary structure |   |
 | T | T | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |
| T | T | T |
|
|  |  |  |
|  |  |  | T | T |  |  |  |
|  |  |  | G | G | G | G |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
475 | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . |
  |