|   |
378 | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | |
|
|
. | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  | . | . | . |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | N | S | I | N | L | P | G | L | Y | L | A | I | N | Y | G | N | A | D | I | V | E | T | I | F | N | S | L | S | E | T | G | Y | E | G | L | L | S | K | K | N | L | M | H | I | L | E | A | K | D | K | N | G | F | S | G | L | F | L | A | I | . |
. |
. |
S | R | K | D | K | N | V | V | T | S | I | L | N | A | L | P |
Query Conservation |   |
  |
|
|   |
|   |
|   |
|
|   |
|   |   |   |
|   |   |
|
|
|
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|   |
|
|
|   |   |
|   |
|
|
|
|   |
|
| . | . | . |   |   |
|
|   |
|
|
|
|   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |
|   |   |
|
|   |   |
|
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | N | R | F | D | R | D | R | L | F | N | A | V | S | R | G | V | P | E | D | L | A | G | L | P | E | Y | L | S | K | T | S | K | . |
. |
. |
. |
. |
. |
. |
Y | L | T | D | S | E | Y | T | E | G | S | T | G | K | T | C | L | X | K | A | V | L | N | L | K | D | G | V | N | A | C | I | L | P | L | L | Q | I | D | R |
Template Known Secondary structure |   |
| S |
|
|
|  |  |  |  |  |  |  |  |  |  | T |
| G | G | G | G | T | T |  |  |  |  |  |  |  |  | T |
| . | . | . | . | . | . | . |
| T | T | S | G | G | G | S | B | T | T | T | T | B |
|  |  |  |  |  |  |  | T |
| B | T | T | B |
| T | T |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
71 | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . |
  |
  |   |
455 | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | L | A | A | T | H | H | L | D | N | E | Q | V | Y | K | F | L | S | A | K | N | R | T | S | S | H | V | L | Y | H | V | M | A | N | G | D | A | D | M | L | K | I | V | L | N | A | L | P | L | L | I | R | T | C | H | L | T | K | E | Q | V | L | D | L | L | K | A | K | D | F | Y | G | C | P | G | L | Y | L | A | M |
Query Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |
|   |
|   |
|
|   |
|   |   |   |
|   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |
|
|
|
|   |
|
|
Alig confidence |   |
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
D | S | . |
. |
. |
. |
G | N | P | Q | P | L | V | N | A | Q | C | T | D | D | Y | Y | R | G | H | S | A | L | H | I | A | I | E | K | R | S | L | Q | C | V | K | L | L | V | E | N | G | A | N | V | H | A | R | A | C | G | . |
. |
R | F | F | Q | K | G | Q | G | T | C | F | Y | F | G | E | L | P | L | S | L | A | A |
Template Known Secondary structure |   |
 |  | . | . | . | . | T |
| S | S |
| G | G | G |
| B |
|
| S | T | T | T | T | T |
| B |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  | T | T |
|
| T | T |
|
|
|
| S | . | . | G | G | G |
| T | T | S | S | S | S |
|
| S |
| S | S |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
144 | . | |
|
|
|
. | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | |
|
. | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . |
  |
  |   |
535 | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | N | G | H | S | D | I | V | K | V | I | L | E | A | L | P | S | L | A | Q | E | I | N | I | S | A | S | D | I | V | D | L | L | T | A | K | S | L | A | R | D | T | G | L | F | M | A | M | Q | R | G | H | M | N | V | I | N | T | I | F | N | A | L | P | T | L | F | N | T | F | K | F | D | K | K | N | M | K | P | L |
Query Conservation |   |
  |   |
|
|   |
|
|
|   |   |
|
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|   |
|
|
|
|   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
C | T | K | Q | W | D | V | V | S | Y | L | L | E | N | P | H | Q | P | A | S | L | Q | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | D | S | Q | G | N | T | V | L | H | A | L | V | X | I | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 | T | T |
|  |  |  |  |  |  |  |  |  |
| S | S |
|
|
|
| T | T |
| . | . | . | . | . | . | . | . | . | . | . | . |
|
| T | T | S |
|
|  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
218 | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
615 | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | L | A | N | N | S | N | E | Y | P | G | L | F | S | A | I | Q | H | K | Q | Q | N | V | V | E | T | V | Y | L | A | L | S | D | H | A | R | L | F | G | F | T | A | E | D | I | M | D | F | W | Q | H | K | A | P | Q | K | Y | S | A | F | E | L | A | F | E | F | G | H | R | V | I | A | E | L | I | L | N | T | L |
Query Conservation |   |
|   |   |
|   |   |
|
|   |
|
|
|
|   |
|
|   |   |
|
|   |   |
|
|   |
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |
|
|
|
|   |
|
|   |   |
|
|   |   |
|
|
|
|
|
|   |   |
|
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |
|   |   |
|   |
|
|
|
|   |
|
|   |   |
|   |   |   |
|
|   |   |
|
|   |
|   |
Template Sequence |   |
. |
. |
. |
D | N | S | A | E | N | I | A | L | V | T | S | X | Y | D | G | L | L | Q | A | G | A | R | L | C | P | T | V | Q | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | D | I | R | N | L | Q | D | L | T | P | L | K | L | A | A | K | E | G | K | I | E | I | F | R | H | I | L | Q | R | E |
Template Known Secondary structure |   |
. | . | . |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T |
|
| G | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | G | G |
|
|
| T | T | S |
|
|  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
. | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
257 | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . |
  |