|   |
388 | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | |
|
|
|
. | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | P | R | A | P | V | V | T | I | M | G | H | V | D | H | G | K | T | S | L | L | D | Y | I | R | S | T | . |
. |
. |
. |
K | V | A | S | G | E | A | G | G | I | T | Q | H | I | G | A | Y | H | V | E | T | E | N | G | M | I | T | F | L | D | T | P | G | H | A | A | F | T | S | M | R | A | R | G | A | Q | A | T | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |   |   |   | . | . | . | . |   |   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|
|
|   |   |   |
|   |   | . | . | . | . |
|
|   |
|
|
Template Sequence |   |
F | G | T | S | L | K | I | G | I | V | G | L | P | N | V | G | K | S | T | F | F | N | V | L | T | N | D | P | N | E | S | R | V | P | V | P | D | E | R | F | D | F | L | C | Q | Y | H | K | P | A | S | K | I | P | A | F | L | N | V | V | D | I | A | G | G | N | A | F | L | S | H | . |
. |
. |
. |
I | S | A | C | D |
Template Known Secondary structure |   |
S | S | S |
|
|
|  |  |  |  |
|
| S | S | S | S |  |  |  |  |  |  |  |  |  |
|
|
| S |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  | . | . | . | . |  |  | T | S | S |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  | . | . | . | . |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
19 | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | |
|
|
|
90 | . | . | . | . |
  |
  |   |
464 | . | . | . | . | . | 470 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
I | V | V | L | V | V | A | A | D | D | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | M | P | Q | T | I | E | A | I | Q | H | A | K | A | A | Q | V | . |
Query Conservation |   |
  |   |   |
|
|
|   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |
|
|   |
|
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | I | F | H | L | T | R | A | V | D | P | I | R | D | I | E | I | I | H | E | E | L | Q | L | K | D | E | E | M | I | G | P | I | I | D | K | L | E | K | V | A | K | P | E | Y | D | I | M | C | K | V | K | S | W | V | I | D | K | P | V | R | F | Y | H | D | W | N | D | K | E | I | E | V | L | N | K | H | L | F | L |
Template Known Secondary structure |   |
S |  |  |  |  |  |  |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| G | G | G |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| G |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
119 | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
492 | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 540 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
P | V | V | V | A | V | N | K | I | D | K | P | E | A | D | P | D | R | V | K | N | E | L | S | Q | Y | G | I | L | P | E | E | W | G | G | E | S | Q | F | V | H | V | S | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | A | G | T | G | I | D | E | L | L | D | A |
Query Conservation |   |
. | . | . |   |   |
|
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |   |   |
|   |   |   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
Template Sequence |   |
T | S | K | P | M | V | Y | L | V | N | L | S | E | K | D | Y | I | R | K | K | N | K | W | L | I | K | I | K | E | . |
. |
W | V | D | K | Y | D | P | G | A | L | V | I | P | F | S | G | A | L | E | L | K | L | Q | E | L | S | A | E | E | R | Q | K | Y | L | E | A | N | M | T | Q | S | A | L | P | K | I | I | K | A |
Template Known Secondary structure |   |
G | G | S |
|  |  |  |  |  |  |
|
|  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |  | . | . |  |  |  |  |  | S | T | T |
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| S |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
221 | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | |
|
250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
  |
  |   |
548 | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | L | L | Q | A | E | V | L | E | L | K | A | V | R | K | G | M | A | S | G | A | V | I | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |
|
|   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |
Template Sequence |   |
G | F | A | A | L | Q | L | E | Y | F | F | T | A | G | P | D | E | V | R | A | W | T | I | R |
Template Known Secondary structure |   |
 |  |  |  | T | T |  |  |  |  |  |  |  | S | S | S |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
299 | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . |
  |