|   |
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | |
. | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | L | T | P | L | N | S | Y | E | N | R | V | Y | Q | F | Q | D | E | . |
D | R | R | R | F | V | V | K | F | Y | R | P | E | R | W | T | A | D | Q | I | L | E | E | H | Q | F | A | L | Q | L | V | N | D | E | V | P | V | A | A | P | V | A | F | N | G | Q | T | L | L | N | H | Q | G | F | Y | F | A | V | F | P | S |
Query Conservation |   |
  |
|   |   |
|   |   |   |
|
|   |
|
|   |
|   |   |   | . |
|
|   |   |   |
|
|
|   |   |
|
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|
|
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
| . |
|
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   | . |
|
|   |
|
|
|
|   |   |
|   |   |
|   |   |
|
|
|   |   |
|
|   |
|
|
|
|
|   |
|   |
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Template Sequence |   |
E | F | Q | I | I | N | G | . |
T | N | I | L | I | K | V | K | D | M | S | K | Q | A | K | Y | L | I | R | L | Y | G | P | . |
T | D | E | I | I | N | R | E | R | E | K | K | I | S | C | I | L | Y | N | K | N | I | A | K | K | I | Y | V | F | F | T | N | G | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | E | E | F |
Template Known Secondary structure |   |
 |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |
|
| . |
|
| S |
| S |
|  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | S | B |
|
|  |  |  |  |  | T | T |  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
| . |
|
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
112 | . | . | . | . | . | . | |
. | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | |
. | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . |
  |
  |   |
109 | 110 | . | . | . | . | . | . | |
|
|
. | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
Query Sequence |   |
V | G | G | R | Q | F | E | A | . |
. |
. |
D | N | I | D | Q | M | E | A | V | G | R | Y | L | G | R | M | H | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | G | R | K | Q | L | F | I | H | R | P | T | I | G | L | N | E | Y | L | I | E | P | R | K | L | F | E | D | A | T | L | I | P | S | G | . |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |
|   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
|   |
|   |
|
|
|   |   |
|
|   |   |
|   |
|   |   |   |
|
|   |   |
|
|   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
M | D | G | Y | A | L | S | R | E | D | I | K | N | P | K | F | Q | K | L | I | A | K | N | L | K | L | L | H | D | I | K | L | N | E | N | L | Y | K | E | L | Q | V | T | Q | K | V | P | G | T | R | P | S | F | L | W | N | T | I | W | K | Y | F | H | L | L | N | E | E | R | K | K | I | C | S | F | D | A | K | A | N |
Template Known Secondary structure |   |
|
| S |  |  |
|
| T | T | T | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | T |
|
| S | S | S |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
| T | T | S | T | T |  |
Template Predicted Secondary structure |   |
 |
|
|  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
183 | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . |
  |
  |   |
|
|
|
|
|
170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | |
|
|
|
. | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 |
Predicted Secondary structure |   |
. | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
| . | . | . | . |  |  |  |  |
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
L | K | A | A | F | L | K | A | T | D | E | L | I | A | A | V | T | A | H | W | R | E | D | F | T | V | L | R | L | H | G | D | C | H | A | G | N | I | L | W | R | D | G | . |
. |
. |
. |
P | M | F | V | D | L | D | D | A | R | N | G | P | A | V | Q | D | L | W | M | L | L | N | G | D | K | A | E |
Query Conservation |   |
. | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|   |   |   |
| . | . | . | . |   |   |
|
|
|
|
|
|   |   |   |
|   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |   | . | . | . |   |   |
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|   |
|   |
|
|
|
|
|
|
|
|
|   |
|   |   |
|
|
Template Sequence |   |
I | L | K | L | I | D | F | D | V | L | R | D | S | I | V | E | V | E | S | L | C | K | R | E | . |
. |
. |
N | S | P | I | V | L | C | H | C | D | L | L | S | S | N | I | I | N | T | V | G | E | G | D | S | I | S | F | I | D | F | E | Y | S | C | P | M | E | R | A | Y | D | I | A | N | H | F | N | E | Y | A | G | F |
Template Known Secondary structure |   |
 |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . | . | T |
|
|  |  |  |  |
| S |
|
|
| G | G | G |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
263 | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | |
|
|
. | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
241 | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | |
|
. | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
Q | R | M | Q | L | E | T | I | I | E | A | Y | E | E | F | S | E | . |
. |
F | D | T | A | E | I | G | L | I | E | P | L | R | A | M | R | L | V | Y | Y | L | A | W |
Query Conservation |   |
. | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   | . | . |
|   |   |   |
|
|   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |
|
|
|   |
|   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |
|   |
|
|
|   |
|
|
|
|
Template Sequence |   |
N | C | D | W | D | L | T | P | S | K | E | E | E | Y | H | F | I | M | H | Y | L | G | T | D | D | E | E | L | I | N | Q | L | I | R | E | I | Q | P | F | Y | I | C | S | H | I | N | W | G | L | W |
Template Known Secondary structure |   |
T | T |
| G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
375 | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . |
  |