Job Description P17888 Confidence 100.00% Date Wed Jan 25 15:20:40 GMT 2012 Rank 7 Aligned Residues 370 % Identity 18% Template c3l9oA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent rna helicase dob1; PDBTitle: crystal structure of mtr4, a co-factor of the nuclear exosome Resolution 3.39 Å

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		179	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	T	P	E	F	S	D	W	R	T	N	Y	A	V	S	G	E	R	L	R	L	N	T	E	Q	A	T	A	V	G	A	I	H	S	A	A	D	T	F	S	A	W	L	L	A	G	V	T	G	S	G	K	T	E	V	Y	L	S	V	L	E	N	V	L	A	Q	G	K	Q	A	L	V	M	V	P	E	I	G	L	T
Query Conservation
Alig confidence																																		.	.	.	.
Template Conservation																																		.	.	.	.
Template Sequence		D	Y	T	P	I	A	E	H	K	R	V	N	E	A	R	T	Y	P	F	T	L	D	P	F	Q	D	T	A	I	S	C	I	.	.	.	.	D	R	G	E	S	V	L	V	S	A	H	T	S	A	G	K	T	V	V	A	E	Y	A	I	A	Q	S	L	K	N	K	Q	R	V	I	Y	T	S	P	I	K	A	L	S
Template Known Secondary structure			S	S	T	T	T	T	T				S		S	S			S	S														.	.	.	.	T	T	T									S	S	S																T	T								S	S
Template Predicted Secondary structure																																		.	.	.	.
Template SS confidence
		130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.					.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.
		259	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310								.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.
Predicted Secondary structure																																																						.	.	.	.	.	.	.
Query SS confidence																																																						.	.	.	.	.	.	.
Query Sequence		P	Q	T	I	A	R	F	R	E	R	F	N	A	P	V	E	V	L	H	S	G	L	N	D	S	E	R	L	S	A	W	L	K	A	K	N	G	E	A	A	I	V	I	G	T	R	S	A	L	F	T	P	.	.	.	.	.	.	.	F	K	N	L	G	V	I	V	I	D	E	E	H	D	S	S	Y	K	Q	Q	E
Query Conservation																																																						.	.	.	.	.	.	.
Alig confidence														.											.	.	.	.	.	.	.	.	.	.	.																			.	.	.	.	.	.	.
Template Conservation														.											.	.	.	.	.	.	.	.	.	.	.
Template Sequence		N	Q	K	Y	R	E	L	L	A	E	F	G	.	D	V	G	L	M	T	G	D	I	T	.	.	.	.	.	.	.	.	.	.	.	I	N	P	D	A	G	C	L	V	M	T	T	E	I	L	R	S	M	L	Y	R	G	S	E	V	M	R	E	V	A	W	V	I	F	D	E	V	H	Y	M	R	D	K	E	R	G
Template Known Secondary structure												T	S	.	S						S	S		B	.	.	.	.	.	.	.	.	.	.	.				S		S																	S	S												T	G	G	G	T	T	S
Template Predicted Secondary structure														.											.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		206	.	.	.	210	.	.	.	.	.	.	.		.	.	220	.	.	.	.	.	.	.												.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.
		332	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.		.	360	.	.	.	.	.	.	.	.		.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.
Predicted Secondary structure																													.											.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																													.											.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		G	W	R	Y	H	A	R	D	L	A	V	Y	R	A	H	S	E	Q	I	P	I	I	L	G	S	A	T	.	P	A	L	E	T	L	C	N	V	Q	.	Q	K	K	Y	R	L	L	R	L	T	R	R	A	G	N	A	R	P	A	I	Q	H	V	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																													.											.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence												.	.	.	.	.													.											.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation												.	.	.	.	.
Template Sequence		V	V	W	E	E	T	I	I	L	L	.	.	.	.	.	P	D	K	V	R	Y	V	F	L	S	A	T	I	P	N	A	M	E	F	A	E	W	I	C	K	I	H	S	Q	P	C	H	I	V	Y	T	N	F	R	P	T	P	L	Q	H	Y	L	F	P	A	H	G	D	G	I	Y	L	V	V	D	E	K	S	T	F
Template Known Secondary structure											S	.	.	.	.	.		T	T	S								S		S	S												T		S											S	S									T	T	S	S								T	T	T
Template Predicted Secondary structure												.	.	.	.	.
Template SS confidence
		274	.	.	.	.	.	280	.	.	.						.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.
		392	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.			420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																														.	.
Query SS confidence																														.	.
Query Sequence		L	D	L	K	G	Q	K	V	Q	A	G	L	A	P	A	L	I	T	R	M	R	Q	H	L	Q	A	D	N	.	.	Q	V	I	L	F	L	N	R	R	G	F	A	P	A	L	L	C	H	D	C	G	W	I	A	E	C	P	R	C	D	H	Y	Y	T	L	H	Q	A	Q	H	H	L	R	C	H	H	C	D	S	Q
Query Conservation																														.	.
Alig confidence																														.	.																												.	.
Template Conservation																																																											.	.
Template Sequence		R	E	E	N	F	Q	K	A	M	A	S	I	A	K	G	D	I	Y	K	I	V	K	M	I	W	K	K	K	Y	N	P	V	I	V	F	S	F	S	K	R	D	C	E	E	L	A	L	K	M	S	K	L	D	F	N	S	D	.	.	A	L	T	K	I	F	N	N	A	I	A	L	L	P	E	T	D	R	E	L	P
Template Known Secondary structure											T	T																T	T									S												T		S							.	.						G	G	G	S		T						T	T
Template Predicted Secondary structure																																																											.	.
Template SS confidence
		349	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.			.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.
		470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	P	V	P	R	Q	C	P	S	C	G	S	T	H	L	V	P	V	G	L	G	T	E	Q	L	E	Q	T	L	A	P	L	F	P	G	V	P	I	S	R	I	D	R	D	T	T	S	R	K	G	A	L	E	Q	Q	L	A	E	V	H	R	G	G	A	R	I	L	I	G	T	Q	M	L	A	K	G	H	H	F	P
Query Conservation
Alig confidence				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.										.	.	.	.	.	.	.
Template Conservation				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.										.	.	.	.	.	.	.
Template Sequence		Q	I	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	K	H	I	L	P	L	L	R	R	.	.	.	.	.	.	.	G	I	G	I	H	H	S	G	L	L	P	I	L	K	E	V	I	E	I	L	F	Q	E	G	F	L	K	V	L	F	A	T	E	T	F	S	I	G	L	N	M	K
Template Known Secondary structure				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.				T						.	.	.	.	.	.	.	T						S		S															T									S				S
Template Predicted Secondary structure				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.										.	.	.	.	.	.	.
Template SS confidence
		460	.																					.	.	.	.	.	.	.	.	470								.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.
		550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.			590	.	.	.	.	.	.	.	.	.	600	.	.	.	.
Predicted Secondary structure																																										.	.
Query SS confidence																																										.	.
Query Sequence		D	V	T	L	V	A	L	L	D	V	D	G	A	L	F	S	A	D	F	R	S	A	E	R	F	A	Q	L	Y	T	Q	V	A	G	R	A	G	R	A	G	.	.	K	Q	G	E	V	V	L	Q	T	H	H	P	E	H	P
Query Conservation																																										.	.
Alig confidence		.	.					.	.	.	.																															.	.
Template Conservation		.	.					.	.	.	.
Template Sequence		.	.	T	V	V	F	.	.	.	.	T	S	V	R	K	W	D	G	Q	Q	F	R	W	V	S	G	G	E	Y	I	Q	M	S	G	R	A	G	R	R	G	L	D	D	R	G	I	V	I	M	M	I	D	E	K	M	E	P
Template Known Secondary structure		.	.					.	.	.	.	S		S				S	S	S																	S			S	S	S		S	S
Template Predicted Secondary structure		.	.					.	.	.	.
Template SS confidence
				515	.	.	.					.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.