Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	E	Q	F	F	R	P	D	S	V	E	Q	A	L	E	L	K	R	R	Y	Q	D	E	A	V	W	F	A	G	G	S	K	L	N	A	T	P	T	R	T	D	K	K	I	A	I	S	L	Q	D	L	E	L	D	W	V	D	W	D
Secondary structure
SS confidence
Disorder		?	?	?	?																																				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		N	G	A	L	R	I	G	A	M	S	R	L	Q	P	L	R	D	A	R	F	I	P	A	A	L	R	E	A	L	G	F	V	Y	S	R	H	V	R	N	Q	S	T	I	G	G	E	I	A	A	R	Q	E	E	S	V	L	L	P	V	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	A	L	D	A	E	L	V	F	G	N	G	E	T	L	S	I	E	D	Y	L	A	C	P	C	D	R	L	L	T	E	I	I	I	K	D	P	Y	R	T	C	A	T	R	K	I	S	R	S	Q	A	G	L	T	V	V	T	A	A	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	M	T	D	H	D	G	M	R	I	A	L	D	G	V	A	S	K	A	L	R	L	H	D	V	E	K	Q	N	L	E	G	N	A	L	E	Q	A	V	A	N	A	I	F	P	Q	E	D	L	R	G	S	V	A	Y	K	R	Y	I	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.
Sequence		G	V	L	V	A	D	L	Y	A	D	C	Q	Q	A	G	E	E	A	V
Secondary structure
SS confidence
Disorder															?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1t3q chain F Region: 4 - 255 Aligned: 251 Modelled: 252 Confidence: 100.0% Identity: 20% PDB header:oxidoreductase Chain: F: PDB Molecule:quinoline 2-oxidoreductase medium subunit; PDBTitle: crystal structure of quinoline 2-oxidoreductase from pseudomonas2 putida 86 Phyre2 PDB 1n62 chain C Region: 1 - 254 Aligned: 254 Modelled: 254 Confidence: 100.0% Identity: 24% PDB header:oxidoreductase Chain: C: PDB Molecule:carbon monoxide dehydrogenase medium chain; PDBTitle: crystal structure of the mo,cu-co dehydrogenase (codh), n-2 butylisocyanide-bound state Phyre2 PDB 3hrd chain C Region: 1 - 256 Aligned: 256 Modelled: 256 Confidence: 100.0% Identity: 24% PDB header:oxidoreductase Chain: C: PDB Molecule:nicotinate dehydrogenase fad-subunit; PDBTitle: crystal structure of nicotinate dehydrogenase Phyre2 PDB 1ffu chain F Region: 1 - 253 Aligned: 253 Modelled: 253 Confidence: 100.0% Identity: 28% PDB header:hydrolase Chain: F: PDB Molecule:cutm, flavoprotein of carbon monoxide PDBTitle: carbon monoxide dehydrogenase from hydrogenophaga2 pseudoflava which lacks the mo-pyranopterin moiety of the3 molybdenum cofactor Phyre2 PDB 2w3r chain G Region: 4 - 259 Aligned: 255 Modelled: 256 Confidence: 100.0% Identity: 23% PDB header:oxidoreductase Chain: G: PDB Molecule:xanthine dehydrogenase; PDBTitle: crystal structure of xanthine dehydrogenase (desulfo form)2 from rhodobacter capsulatus in complex with hypoxanthine Phyre2 PDB 1wyg chain A Region: 3 - 256 Aligned: 253 Modelled: 254 Confidence: 100.0% Identity: 20% PDB header:oxidoreductase Chain: A: PDB Molecule:xanthine dehydrogenase/oxidase; PDBTitle: crystal structure of a rat xanthine dehydrogenase triple mutant2 (c535a, c992r and c1324s) Phyre2 PDB 3etr chain M Region: 4 - 256 Aligned: 252 Modelled: 253 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: M: PDB Molecule:xanthine dehydrogenase/oxidase; PDBTitle: crystal structure of xanthine oxidase in complex with2 lumazine Phyre2 PDB 3b9j chain J Region: 4 - 256 Aligned: 252 Modelled: 253 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: J: PDB Molecule:xanthine oxidase; PDBTitle: structure of xanthine oxidase with 2-hydroxy-6-methylpurine Phyre2 PDB 1rm6 chain E Region: 1 - 254 Aligned: 250 Modelled: 254 Confidence: 100.0% Identity: 22% PDB header:oxidoreductase Chain: E: PDB Molecule:4-hydroxybenzoyl-coa reductase beta subunit; PDBTitle: structure of 4-hydroxybenzoyl-coa reductase from thauera2 aromatica Phyre2 PDB 1n62 chain C domain 2 Region: 1 - 158 Aligned: 158 Modelled: 158 Confidence: 100.0% Identity: 25% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 1ffv chain C domain 2 Region: 1 - 159 Aligned: 159 Modelled: 159 Confidence: 100.0% Identity: 25% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 1t3q chain C domain 2 Region: 4 - 157 Aligned: 153 Modelled: 154 Confidence: 100.0% Identity: 22% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 1v97 chain A domain 6 Region: 4 - 159 Aligned: 155 Modelled: 156 Confidence: 100.0% Identity: 21% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 1rm6 chain B domain 2 Region: 1 - 158 Aligned: 156 Modelled: 158 Confidence: 100.0% Identity: 23% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 1jro chain A domain 4 Region: 5 - 157 Aligned: 152 Modelled: 153 Confidence: 100.0% Identity: 25% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 3b9j chain B domain 2 Region: 4 - 159 Aligned: 155 Modelled: 156 Confidence: 100.0% Identity: 21% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 1v97 chain A domain 4 Region: 157 - 256 Aligned: 100 Modelled: 100 Confidence: 99.9% Identity: 16% Fold: CO dehydrogenase flavoprotein C-domain-like Superfamily: CO dehydrogenase flavoprotein C-terminal domain-like Family: CO dehydrogenase flavoprotein C-terminal domain-like Phyre2 PDB 1jro chain A domain 3 Region: 158 - 259 Aligned: 102 Modelled: 102 Confidence: 99.9% Identity: 21% Fold: CO dehydrogenase flavoprotein C-domain-like Superfamily: CO dehydrogenase flavoprotein C-terminal domain-like Family: CO dehydrogenase flavoprotein C-terminal domain-like Phyre2 PDB 1t3q chain C domain 1 Region: 160 - 256 Aligned: 97 Modelled: 97 Confidence: 99.8% Identity: 18% Fold: CO dehydrogenase flavoprotein C-domain-like Superfamily: CO dehydrogenase flavoprotein C-terminal domain-like Family: CO dehydrogenase flavoprotein C-terminal domain-like Phyre2 PDB 1n62 chain C domain 1 Region: 158 - 253 Aligned: 96 Modelled: 96 Confidence: 99.8% Identity: 22% Fold: CO dehydrogenase flavoprotein C-domain-like Superfamily: CO dehydrogenase flavoprotein C-terminal domain-like Family: CO dehydrogenase flavoprotein C-terminal domain-like Phyre2 1 c1t3qF_ 2 c1n62C_ 3 c3hrdC_ 4 c1ffuF_ 5 c2w3rG_ 6 c1wygA_ 7 c3etrM_ 8 c3b9jJ_ 9 c1rm6E_ 10 d1n62c2 11 d1ffvc2 12 d1t3qc2 13 d1v97a6 14 d1rm6b2 15 d1jroa4 16 d3b9jb2 17 d1v97a4 18 d1jroa3 19 d1t3qc1 20 d1n62c1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1t3qF_ 100.0 20 PDB header:oxidoreductase Chain: F: PDB Molecule:quinoline 2-oxidoreductase medium subunit; PDBTitle: crystal structure of quinoline 2-oxidoreductase from pseudomonas2 putida 86 2 c1n62C_ 100.0 24 PDB header:oxidoreductase Chain: C: PDB Molecule:carbon monoxide dehydrogenase medium chain; PDBTitle: crystal structure of the mo,cu-co dehydrogenase (codh), n-2 butylisocyanide-bound state 3 c3hrdC_ 100.0 24 PDB header:oxidoreductase Chain: C: PDB Molecule:nicotinate dehydrogenase fad-subunit; PDBTitle: crystal structure of nicotinate dehydrogenase 4 c1ffuF_ 100.0 28 PDB header:hydrolase Chain: F: PDB Molecule:cutm, flavoprotein of carbon monoxide PDBTitle: carbon monoxide dehydrogenase from hydrogenophaga2 pseudoflava which lacks the mo-pyranopterin moiety of the3 molybdenum cofactor 5 c2w3rG_ 100.0 23 PDB header:oxidoreductase Chain: G: PDB Molecule:xanthine dehydrogenase; PDBTitle: crystal structure of xanthine dehydrogenase (desulfo form)2 from rhodobacter capsulatus in complex with hypoxanthine 6 c1wygA_ 100.0 20 PDB header:oxidoreductase Chain: A: PDB Molecule:xanthine dehydrogenase/oxidase; PDBTitle: crystal structure of a rat xanthine dehydrogenase triple mutant2 (c535a, c992r and c1324s) 7 c3etrM_ 100.0 19 PDB header:oxidoreductase Chain: M: PDB Molecule:xanthine dehydrogenase/oxidase; PDBTitle: crystal structure of xanthine oxidase in complex with2 lumazine 8 c3b9jJ_ 100.0 19 PDB header:oxidoreductase Chain: J: PDB Molecule:xanthine oxidase; PDBTitle: structure of xanthine oxidase with 2-hydroxy-6-methylpurine 9 c1rm6E_ 100.0 22 PDB header:oxidoreductase Chain: E: PDB Molecule:4-hydroxybenzoyl-coa reductase beta subunit; PDBTitle: structure of 4-hydroxybenzoyl-coa reductase from thauera2 aromatica 10 d1n62c2 100.0 25 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CO dehydrogenase flavoprotein N-terminal domain-like 11 d1ffvc2 100.0 25 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CO dehydrogenase flavoprotein N-terminal domain-like 12 d1t3qc2 100.0 22 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CO dehydrogenase flavoprotein N-terminal domain-like 13 d1v97a6 100.0 21 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CO dehydrogenase flavoprotein N-terminal domain-like 14 d1rm6b2 100.0 23 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CO dehydrogenase flavoprotein N-terminal domain-like 15 d1jroa4 100.0 25 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CO dehydrogenase flavoprotein N-terminal domain-like 16 d3b9jb2 100.0 21 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CO dehydrogenase flavoprotein N-terminal domain-like 17 d1v97a4 99.9 16 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:CO dehydrogenase flavoprotein C-terminal domain-like Family:CO dehydrogenase flavoprotein C-terminal domain-like 18 d1jroa3 99.9 21 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:CO dehydrogenase flavoprotein C-terminal domain-like Family:CO dehydrogenase flavoprotein C-terminal domain-like 19 d1t3qc1 99.8 18 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:CO dehydrogenase flavoprotein C-terminal domain-like Family:CO dehydrogenase flavoprotein C-terminal domain-like 20 d1n62c1 99.8 22 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:CO dehydrogenase flavoprotein C-terminal domain-like Family:CO dehydrogenase flavoprotein C-terminal domain-like 21 d1ffvc1 not modelled 99.8 30 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:CO dehydrogenase flavoprotein C-terminal domain-like Family:CO dehydrogenase flavoprotein C-terminal domain-like 22 d1rm6b1 not modelled 99.8 22 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:CO dehydrogenase flavoprotein C-terminal domain-like Family:CO dehydrogenase flavoprotein C-terminal domain-like 23 c2wdwB_ not modelled 97.8 19 PDB header:oxidoreductase Chain: B: PDB Molecule:putative hexose oxidase; PDBTitle: the native crystal structure of the primary hexose oxidase (2 dbv29) in antibiotic a40926 biosynthesis 24 c2uuvC_ not modelled 97.7 18 PDB header:transferase Chain: C: PDB Molecule:alkyldihydroxyacetonephosphate synthase; PDBTitle: alkyldihydroxyacetonephosphate synthase in p1 25 c3fwaA_ not modelled 97.7 20 PDB header:flavoprotein Chain: A: PDB Molecule:reticuline oxidase; PDBTitle: structure of berberine bridge enzyme, c166a variant in complex with2 (s)-reticuline 26 c2vfvA_ not modelled 97.6 19 PDB header:oxidoreductase Chain: A: PDB Molecule:xylitol oxidase; PDBTitle: alditol oxidase from streptomyces coelicolor a3(2): complex2 with sulphite 27 c2ipiD_ not modelled 97.3 14 PDB header:oxidoreductase Chain: D: PDB Molecule:aclacinomycin oxidoreductase (aknox); PDBTitle: crystal structure of aclacinomycin oxidoreductase 28 d1hska1 not modelled 97.3 16 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain 29 c3popD_ not modelled 97.1 15 PDB header:oxidoreductase Chain: D: PDB Molecule:gilr oxidase; PDBTitle: the crystal structure of gilr, an oxidoreductase that catalyzes the2 terminal step of gilvocarcin biosynthesis 30 c1zr6A_ not modelled 97.1 16 PDB header:oxidoreductase Chain: A: PDB Molecule:glucooligosaccharide oxidase; PDBTitle: the crystal structure of an acremonium strictum glucooligosaccharide2 oxidase reveals a novel flavinylation 31 c2y3rC_ not modelled 97.0 15 PDB header:oxidoreductase Chain: C: PDB Molecule:taml; PDBTitle: structure of the tirandamycin-bound fad-dependent2 tirandamycin oxidase taml in p21 space group 32 c3bw7A_ not modelled 97.0 17 PDB header:oxidoreductase Chain: A: PDB Molecule:cytokinin dehydrogenase 1; PDBTitle: maize cytokinin oxidase/dehydrogenase complexed with the allenic2 cytokinin analog ha-1 33 c1f0xA_ not modelled 97.0 15 PDB header:oxidoreductase Chain: A: PDB Molecule:d-lactate dehydrogenase; PDBTitle: crystal structure of d-lactate dehydrogenase, a peripheral2 membrane respiratory enzyme. 34 c3d2hA_ not modelled 97.0 20 PDB header:oxidoreductase Chain: A: PDB Molecule:berberine bridge-forming enzyme; PDBTitle: structure of berberine bridge enzyme from eschscholzia californica,2 monoclinic crystal form 35 d1f0xa2 not modelled 96.8 16 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:FAD-linked oxidases, N-terminal domain 36 c2bvfA_ not modelled 96.7 21 PDB header:oxidase Chain: A: PDB Molecule:6-hydroxy-d-nicotine oxidase; PDBTitle: crystal structure of 6-hydoxy-d-nicotine oxidase from2 arthrobacter nicotinovorans. crystal form 3 (p1) 37 c1hskA_ not modelled 96.7 17 PDB header:oxidoreductase Chain: A: PDB Molecule:udp-n-acetylenolpyruvoylglucosamine reductase; PDBTitle: crystal structure of s. aureus murb 38 c1mbbA_ not modelled 96.6 14 PDB header:oxidoreductase Chain: A: PDB Molecule:uridine diphospho-n-acetylenolpyruvylglucosamine PDBTitle: oxidoreductase 39 c2exrA_ not modelled 96.6 13 PDB header:oxidoreductase Chain: A: PDB Molecule:cytokinin dehydrogenase 7; PDBTitle: x-ray structure of cytokinin oxidase/dehydrogenase (ckx)2 from arabidopsis thaliana at5g21482 40 c3pm9A_ not modelled 96.3 21 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a putative dehydrogenase (rpa1076) from2 rhodopseudomonas palustris cga009 at 2.57 a resolution 41 d2i0ka2 not modelled 96.3 13 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:FAD-linked oxidases, N-terminal domain 42 c3js8A_ not modelled 96.1 14 PDB header:oxidoreductase Chain: A: PDB Molecule:cholesterol oxidase; PDBTitle: solvent-stable cholesterol oxidase 43 c3i99A_ not modelled 95.7 16 PDB header:oxidoreductase Chain: A: PDB Molecule:udp-n-acetylenolpyruvoylglucosamine reductase; PDBTitle: the crystal structure of the udp-n-acetylenolpyruvoylglucosamine2 reductase from the vibrio cholerae o1 biovar tor 44 c1i19B_ not modelled 95.6 13 PDB header:oxidoreductase Chain: B: PDB Molecule:cholesterol oxidase; PDBTitle: crystal structure of cholesterol oxidase from b.sterolicum 45 d1wvfa2 not modelled 95.3 10 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:FAD-linked oxidases, N-terminal domain 46 c1wveB_ not modelled 95.1 10 PDB header:oxidoreductase Chain: B: PDB Molecule:4-cresol dehydrogenase [hydroxylating] PDBTitle: p-cresol methylhydroxylase: alteration of the structure of2 the flavoprotein subunit upon its binding to the3 cytochrome subunit 47 d1uxya1 not modelled 94.1 14 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain 48 c1ahuB_ not modelled 92.8 8 PDB header:flavoenzyme Chain: B: PDB Molecule:vanillyl-alcohol oxidase; PDBTitle: structure of the octameric flavoenzyme vanillyl-alcohol2 oxidase in complex with p-cresol 49 d1e8ga2 not modelled 91.0 8 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:FAD-linked oxidases, N-terminal domain 50 c2gquA_ not modelled 86.6 21 PDB header:oxidoreductase Chain: A: PDB Molecule:udp-n-acetylenolpyruvylglucosamine reductase; PDBTitle: crystal structure of udp-n-acetylenolpyruvylglucosamine2 reductase (murb) from thermus caldophilus 51 d1w1oa2 not modelled 85.3 13 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:FAD-linked oxidases, N-terminal domain 52 c2yvsA_ not modelled 83.2 15 PDB header:oxidoreductase Chain: A: PDB Molecule:glycolate oxidase subunit glce; PDBTitle: crystal structure of glycolate oxidase subunit glce from thermus2 thermophilus hb8 53 d1j3ka_ not modelled 38.8 22 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 54 c2blcA_ not modelled 38.8 25 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrofolate reductase-thymidylate synthase; PDBTitle: sp21 double mutant p. vivax dihydrofolate reductase in2 complex with des-chloropyrimethamine 55 d3dfra_ not modelled 26.0 19 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 56 d1a9xa3 not modelled 24.1 17 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 57 c3dg8B_ not modelled 20.4 22 PDB header:oxidoreductase, transferase Chain: B: PDB Molecule:bifunctional dihydrofolate reductase-thymidylate PDBTitle: quadruple mutant (n51i+c59r+s108n+i164l) plasmodium2 falciparum dihydrofolate reductase-thymidylate synthase3 (pfdhfr-ts) complexed with rjf670, nadph, and dump 58 c3jsuA_ not modelled 12.3 22 PDB header:oxidoreductase, transferase Chain: A: PDB Molecule:dihydrofolate reductase-thymidylate synthase; PDBTitle: quadruple mutant(n51i+c59r+s108n+i164l) plasmodium falciparum2 dihydrofolate reductase-thymidylate synthase(pfdhfr-ts) complexed3 with qn254, nadph, and dump 59 d1i1ga2 not modelled 11.9 16 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Lrp/AsnC-like transcriptional regulator C-terminal domain 60 d1qwga_ not modelled 11.6 13 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 61 d1u83a_ not modelled 11.4 13 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 62 c1u83A_ not modelled 11.4 13 PDB header:lyase Chain: A: PDB Molecule:phosphosulfolactate synthase; PDBTitle: psl synthase from bacillus subtilis 63 c2kr1A_ not modelled 10.4 21 PDB header:ligase Chain: A: PDB Molecule:ubiquitin protein ligase e3a; PDBTitle: solution nmr structure of zinc binding n-terminal domain of ubiquitin-2 protein ligase e3a from homo sapiens. northeast structural genomics3 consortium (nesg) target hr3662 64 d1vdra_ not modelled 10.0 25 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 65 c2e1aD_ not modelled 9.4 12 PDB header:transcription Chain: D: PDB Molecule:75aa long hypothetical regulatory protein asnc; PDBTitle: crystal structure of ffrp-dm1 66 d1jr1a4 not modelled 9.4 21 Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair 67 c3q94B_ not modelled 9.4 9 PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase, class ii; PDBTitle: the crystal structure of fructose 1,6-bisphosphate aldolase from2 bacillus anthracis str. 'ames ancestor' 68 d1mo1a_ not modelled 9.2 7 Fold:HPr-like Superfamily:HPr-like Family:HPr-like 69 d1gvfa_ not modelled 9.1 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class II FBP aldolase 70 c2zxkB_ not modelled 9.0 4 PDB header:oxidoreductase Chain: B: PDB Molecule:red chlorophyll catabolite reductase, PDBTitle: crystal structure of semet-red chlorophyll catabolite2 reductase 71 c3e0bA_ not modelled 8.9 33 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrofolate reductase; PDBTitle: bacillus anthracis dihydrofolate reductase complexed with2 nadph and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-3 ynyl)-6-ethylpyrimidine (ucp120b) 72 c2dyoB_ not modelled 8.8 56 PDB header:protein turnover/protein turnover Chain: B: PDB Molecule:autophagy protein 16; PDBTitle: the crystal structure of saccharomyces cerevisiae atg5-2 atg16(1-57) complex 73 d1li4a2 not modelled 8.7 20 Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:S-adenosylhomocystein hydrolase 74 d1ou0a_ not modelled 8.4 20 Fold:Flavodoxin-like Superfamily:Precorrin-8X methylmutase CbiC/CobH Family:Precorrin-8X methylmutase CbiC/CobH 75 c1zdrB_ not modelled 8.2 20 PDB header:oxidoreductase Chain: B: PDB Molecule:dihydrofolate reductase; PDBTitle: dhfr from bacillus stearothermophilus 76 d1v8ba2 not modelled 7.2 13 Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:S-adenosylhomocystein hydrolase 77 c3ihsB_ not modelled 7.0 9 PDB header:transport protein Chain: B: PDB Molecule:phosphocarrier protein hpr; PDBTitle: crystal structure of a phosphocarrier protein hpr from2 bacillus anthracis str. ames 78 c3dhyC_ not modelled 6.6 22 PDB header:hydrolase Chain: C: PDB Molecule:adenosylhomocysteinase; PDBTitle: crystal structures of mycobacterium tuberculosis s-adenosyl-l-2 homocysteine hydrolase in ternary complex with substrate and3 inhibitors 79 c2djwF_ not modelled 6.6 25 PDB header:unknown function Chain: F: PDB Molecule:probable transcriptional regulator, asnc family; PDBTitle: crystal structure of ttha0845 from thermus thermophilus hb8 80 d1aoea_ not modelled 6.5 23 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 81 d1t6t1_ not modelled 6.3 21 Fold:Toprim domain Superfamily:Toprim domain Family:Toprim domain 82 d1a9xa4 not modelled 6.1 30 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 83 c2zbcH_ not modelled 6.0 11 PDB header:transcription Chain: H: PDB Molecule:83aa long hypothetical transcriptional regulator asnc; PDBTitle: crystal structure of sts042, a stand-alone ram module protein, from2 hyperthermophilic archaeon sulfolobus tokodaii strain7. 84 d1cm3a_ not modelled 5.9 13 Fold:HPr-like Superfamily:HPr-like Family:HPr-like 85 c3gxxB_ not modelled 5.9 17 PDB header:transcription Chain: B: PDB Molecule:transcription elongation factor spt6; PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b 86 d1ou5a2 not modelled 5.8 17 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:Poly A polymerase head domain-like 87 c3d64A_ not modelled 5.8 18 PDB header:hydrolase Chain: A: PDB Molecule:adenosylhomocysteinase; PDBTitle: crystal structure of s-adenosyl-l-homocysteine hydrolase from2 burkholderia pseudomallei 88 c3oneA_ not modelled 5.7 18 PDB header:hydrolase/hydrolase substrate Chain: A: PDB Molecule:adenosylhomocysteinase; PDBTitle: crystal structure of lupinus luteus s-adenosyl-l-homocysteine2 hydrolase in complex with adenine 89 c1v8bA_ not modelled 5.6 13 PDB header:hydrolase Chain: A: PDB Molecule:adenosylhomocysteinase; PDBTitle: crystal structure of a hydrolase 90 d2cg4a2 not modelled 5.2 12 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Lrp/AsnC-like transcriptional regulator C-terminal domain 91 c3e56A_ not modelled 5.2 10 PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: the 2.0 angstrom resolution crystal structure of npr1517, a putative2 heterocyst differentiation inhibitor from nostoc punctiforme 92 c3n58D_ not modelled 5.2 20 PDB header:hydrolase Chain: D: PDB Molecule:adenosylhomocysteinase; PDBTitle: crystal structure of s-adenosyl-l-homocysteine hydrolase from brucella2 melitensis in ternary complex with nad and adenosine, orthorhombic3 form

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0