Job Description P30011 Confidence 65.85% Date Thu Jan 5 11:45:42 GMT 2012 Rank 312 Aligned Residues 126 % Identity 20% Template c2cw6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Resolution 2.10 Å

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		133	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.												150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.
Predicted Secondary structure																			.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																			.	.	.	.	.	.	.	.	.	.	.
Query Sequence		S	K	V	R	H	Y	V	E	L	L	E	G	T	N	T	Q	L	.	.	.	.	.	.	.	.	.	.	.	L	D	T	R	K	T	L	P	G	L	R	S	A	L	K	Y	A	V	L	C	G	G	G	A	N	H	R	L	G	L	S	D	A	F	L	I	K	E	N	H	I	I	A	S	G	S	V	R	Q	A	V	E
Query Conservation																			.	.	.	.	.	.	.	.	.	.	.
Alig confidence																			.	.	.	.	.	.	.	.	.	.	.																						.	.	.																		.	.	.	.	.
Template Conservation																																																			.	.	.																		.	.	.	.	.
Template Sequence		Q	R	F	D	A	I	L	K	A	A	Q	S	A	N	I	S	V	R	G	Y	V	S	C	A	L	G	C	P	Y	E	G	K	I	S	P	A	K	V	A	E	V	T	K	K	F	Y	S	M	G	.	.	.	C	Y	E	I	S	L	G	D	T	I	G	V	G	T	P	G	I	.	.	.	.	.	M	K	D	M	L	S
Template Known Secondary structure														T	T									S	T	T		B	T	T	T	B	S																T	T	.	.	.		S							T	T								.	.	.	.	.
Template Predicted Secondary structure																																																			.	.	.																		.	.	.	.	.
Template SS confidence
		148	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.				.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.						.	.	.	.	.	.
		202	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.						.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.																.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.
Predicted Secondary structure																			.	.	.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																			.	.	.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		K	A	S	W	L	H	P	D	A	P	V	E	V	E	V	E	N	.	.	.	.	.	L	E	E	L	D	E	A	L	K	A	G	A	D	I	I	M	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	D	N	F	E	T	E	Q	M	R	E	A	V	K	R	T	N	G	K	A	L	L	E	V	S	G	N
Query Conservation																			.	.	.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																			.	.	.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.	.	.	.	.	.
Template Conservation																																																																								.	.	.	.	.	.
Template Sequence		A	V	M	Q	E	V	P	L	A	A	L	A	V	H	C	H	D	T	Y	G	Q	A	L	A	N	T	L	M	A	L	Q	M	G	V	S	V	V	D	S	S	V	A	G	L	G	G	C	P	Y	A	Q	G	A	S	G	N	L	A	T	E	D	L	V	Y	M	L	E	G	L	G	.	.	.	.	.	.	I	H	T	G
Template Known Secondary structure							S		G	G	G						B		T	T	S												T	T							B	T	T	S					T	T	S	S	S				B		B											T	T	.	.	.	.	.	.		B
Template Predicted Secondary structure																																																																								.	.	.	.	.	.
Template SS confidence
		220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.							290	.	.	.
		262	.	.	.	.	.	.	.	270	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	T	D	K	T	L	R	E	F	A	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	N	L	Q	K	L	L	E	A	G	N
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		294	.	.	.	.	.	300	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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