|   |
31 | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | T | D | V | L | L | I | G | G | G | I | M | S | A | T | L | G | T | Y | L | R | E | L | E | P | E | W | S | M | T | M | V | E | R | L | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | V | A | Q | E | S | S | N | G | W | N | N | A | G | T | G | H | S | A | L | M | E | L | N | Y | T | P |
Query Conservation |   |
  |   |
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|   |   |
|
|
|   |   |
|
|   |   |
|   |
|
|
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |
|
|   |   |   |   |
|
|
|   |
|
|   |
|   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|
|
|   |   |
|   |   |   |
|   |   |
|
|   | . |   |   |
|   |   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | F | D | Y | V | V | V | G | A | G | N | A | G | N | V | V | A | A | R | L | T | E | . |
D | P | D | V | S | V | L | V | L | E | A | G | V | S | D | E | N | V | L | G | A | E | A | P | L | L | A | P | G | L | V | P | N | S | I | F | D | W | N | Y | T | T | T | A | Q | A | G | Y | N | G | R | S | I | A | Y | P | R |
Template Known Secondary structure |   |
|  |  |  |  |  | S |
|
| S | T | T |  |  |  |  |  |  |  |  | T | T | . | S | T | T |
|
|  |  |  |  |
| S | S | B |
|
| T | T |
| G | G | G | T | S | G | G | G | S | G | G | G | S | S | S | S | T | T | B |
|
|
| B |
|
|
|
| G | G | G | T | T |
|
|
| B |
|
|
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | |
. | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
  |
  |   |
94 | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
Q | N | A | D | G | S | I | S | I | E | K | A | V | A | I | N | E | A | F | Q | I | S | R | Q | F | W | A | H | Q | V | E | R | G | V | L | R | T | P | R | S | F | I | N | T | V | P | H | M | S | F | V | W | G | E | D | N | V | N | F | L | R | A | R | Y | A | A | L | Q | Q | S | S | L | F | R | G | M | R | Y | S | . |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
|   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | R | M | L | G | G | S | S | S | V | H | Y | M | V | M | M | R | G | S | T | E | D | F | D | R | Y | A | A | V | T | G | D | E | G | W | N | W | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | N | I | Q | Q | F | V | R | K | N | E | M | V | V | P | P | A | D | N | H | N | T | S |
Template Known Secondary structure |   |
B |
| B | T | T | G | G | G | G | T | S |
|
| B |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | T |
| T | T | S | S |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T |
|
|
|
| T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
173 | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | |
210 | . | . | . | . | . | . | . | . | . | 220 | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |
|  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | D | H | A | Q | I | K | E | W | A | P | L | V | M | E | G | R | D | P | Q | Q | K | V | A | A | T | R | T | E | I | G | T | D | V | N | Y | G | . |
E | I | T | R | Q | L | I | A | S | L | Q | K | K |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |
|
|   |   | . |   |
|   |   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |
Template Sequence |   |
G | E | F | I | P | A | V | H | G | T | N | G | S | V | S | I | S | L | P | G | F | P | T | P | L | D | D | R | V | L | A | T | T | Q | E | Q | S | E | E | F | F | F | N | P | D | M | G | T | G | H | P | L | G | I | S | W | S | I | A | S | V | G | N | G | Q | R | S | S | S | S | T | A | Y | L | R | P | A | Q | S | R |
Template Known Secondary structure |   |
T | T | S |
| G | G | G | S |
| B | S | S | S |  |  |  | B | S |
| S | S |
|
| T |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |
| B |
| S |
| G | G | G | S |
|
|
|  |  |  |  |
|
| B | S |  |  | T | T |  |  |
|
|  |  |  |  | T |  |  |  |  | T | T |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
141 | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 |
  |
  |   |
223 | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | |
. | . | . | . | . | . | . | . | 270 | |
. | . | . | . | . | . | . | . | . | 280 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
| . |
|  |  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
S | N | F | S | L | Q | L | S | S | E | V | R | A | L | K | R | N | D | D | N | . |
. |
. |
. |
. |
T | W | T | V | T | V | A | D | L | K | N | G | T | A | Q | N | I | R | A | . |
K | F | V | F | I | G | A | G | G | . |
A | A | L | K | L | L | Q | E | S | G | I | P | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |
|
|   |
|   |   |   |
|   |
|   |   |
|   |   |   |   |
|
| . | . | . | . | . |   |   |   |
|   |
|   |   |   |   |
|
|   |   |   |   |
|   |
| . |
|   |
|
|
|
|
|
|
| . |   |
|   |   |
|
|   |   |
|
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|
|
|
|
|
|
|
|   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |
Template Sequence |   |
P | N | L | S | V | L | I | N | A | Q | V | T | K | L | V | N | S | G | T | T | N | G | L | P | A | F | R | C | V | E | Y | A | E | Q | E | G | A | P | T | T | T | V | C | A | K | K | E | V | V | L | S | A | G | S | V | G | T | P | I | L | L | Q | L | S | G | I | G | D | E | N | D | L | S | S | V | G | I | D | T | I |
Template Known Secondary structure |   |
T | T |  |  |  |  | S | S |
|  |  |  |  |  |  |
|
|  |  |  | T | T |  |  |  |
|
|  |  |  |  |  | S | S | T | T | S |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
|  |  |  |  |  |  | T | T |
|
|
| S |
Template Predicted Secondary structure |   |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
221 | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 |
  |
  |   |
|
|
|
|
|
|
284 | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
A | K | D | Y | A | G | F | P | V | G | G | Q | F | L | V | S | E | N | P |
Query Conservation |   |
. | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | N | N | P | S | V | G | R | N | L | S | D | H | L | L | L | P | A | A | F | F | V | N | S | N |
Template Known Secondary structure |   |
 |  |
| T | T | T | T |
| S | B | B |
|
|  |  |  |
|
|  |  |  |  | S |
| S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
301 | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . |
  |