|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | N | K | Y | Q | A | V | I | I | G | F | G | K | A | G | K | T | L | A | V | T | L | A | K | A | G | W | R | V | A | L | I | E | Q | S | N | A | M | Y | G | G | T | C | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | I | G | C | I | P | T | K | T | L | V | H | D | A | Q | Q | H | T | D | F | V |
Query Conservation |   |
|
|   |
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |
|
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
X | Q | H | H | K | V | A | I | I | G | A | G | A | A | G | I | G | X | A | I | T | L | K | D | F | G | I | T | D | V | I | I | L | E | K | G | T | V | G | H | S | F | K | H | W | P | K | S | T | R | T | I | T | P | S | F | T | S | N | G | F | G | X | P | D | X | N | A | I | S | X | D | T | S | P | A | F | T | F | N |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |
| S | S | S | T | T |  |  |  |  | T | S |
| T | T |
| B |
| S | S |
|
|
|
|
| G | G | G | T |
|
|
| T | T |
| S | S | T | T |
|
|  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
  |
  |   |
66 | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | A | I | Q | R | K | N | E | V | V | N | F | L | R | N | K | N | F | H | N | L | A | D | M | P | N | I | D | V | I | D | G | Q | A | E | F | I | N | N | H | S | L | R | V | H | R | P | E | G | N | L | E | I | H | G | E | K | I | F | I | N | T | G | A | Q | T | V | V | P | P | I | P | G | I | T | T | T | P | G | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |
Template Sequence |   |
E | E | H | I | S | G | E | T | Y | A | E | Y | L | Q | V | V | A | N | H | Y | . |
. |
E | L | N | I | F | E | N | T | V | V | T | N | I | S | A | D | D | A | Y | Y | T | I | A | T | T | T | E | T | Y | H | A | D | Y | I | F | V | A | T | G | D | Y | N | F | P | K | K | P | F | K | Y | G | . |
. |
. |
. |
. |
. |
I |
Template Known Secondary structure |   |
| S | S |
| B |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | T |
|  |  |  |
| S |
|
|  |  |  |  |  |  |
| S | S | S |  |  |  |  |  | S | S |
|
|  |  |  |  |  |  |  |  |
|
|
| S | T | T | S | B |
|
|
| S | S | S |
| . | . | . | . | . | . |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | |
|
. | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | |
|
|
|
|
|
. |
  |
  |   |
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | D | S | T | G | L | L | N | L | K | E | L | P | G | H | L | G | I | L | G | G | G | Y | I | G | V | E | F | A | S | M | F | A | N | F | G | S | K | V | T | I | L | E | A | A | S | L | F | L | P | R | E | D | R | D | I | A | D | N | I | A | T | I | L | R | D | Q | G | V | D | I | I | L | N | A | H | V | E | R | I |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |
|   |   |
|   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
H | Y | S | E | I | E | D | F | D | N | F | N | K | G | Q | Y | V | V | I | G | G | N | E | S | G | F | D | A | A | Y | Q | L | A | K | N | G | S | D | I | A | L | Y | T | S | P | S | V | R | L | S | . |
. |
P | Y | T | R | Q | R | L | G | N | V | I | K | Q | G | A | R | I | E | X | N | V | H | Y | T | V | K | D | I |
Template Known Secondary structure |   |
 | G | G | G |
| S |
| G | G | G | S |
| S | S |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
|
|
| T | T | S |
|
| . | . |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
| S |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  |
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
153 | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | |
|
. | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 |
  |
  |   |
226 | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | |
|
. | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | |
|
|
|
Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  | . | . |
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
S | H | H | E | N | Q | V | Q | V | H | S | E | H | A | Q | L | . |
. |
A | V | D | A | L | L | I | A | S | G | R | Q | P | A | T | A | S | L | H | P | E | N | A | G | I | A | V | N | E | R | G | A | I | V | V | D | K | R | L | H | T | T | A | D | N | I | W | A | M | G | D | V | T | G | G | L | Q | F | . |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
| . | . |   |   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |
|   |   |   |   |
|
|
|   |
|
|   |   |   |   |   |   |   | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | F | N | N | G | Q | Y | H | I | S | F | D | S | G | Q | S | V | H | T | P | H | E | P | I | L | A | T | G | F | D | A | T | K | N | P | I | V | Q | Q | L | F | . |
. |
V | T | T | N | Q | D | I | K | L | T | T | H | D | E | S | T | R | Y | P | N | I | F | X | I | G | A | T | V | E | N | D | N | A | K | L | C | Y |
Template Known Secondary structure |   |
 |  |  | T | T |  |  |  |  |  |  | S | S | S |
|
|  |  |  | S | S |
|
|  |  |
|
|
| B |
| G | G | G | S |  |  |  |  |  |  | S | . | . |
|
| T | T | S |
|
|
| B |
| T | T | S | B | B | S | S | S | T | T |  |  |  |
| S | T | T |
|
|
| S | S |
|
|
|
| S |
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |
|  |  |
|
|  |  |  |  |  |  |
|
|
| . | . |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
241 | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | |
|
. | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . |
  |
  |   |
300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | Y | I | S | L | D | D | Y | R | I | V | R | D | E | L | L | G |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
Template Sequence |   |
I | Y | K | F | R | A | R | F | A | V | L | A | H | L | L | T | Q |
Template Known Secondary structure |   |
 |  |  |  | G | G | G |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
319 | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . |
  |