|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | K | Y | Q | A | V | I | I | G | F | G | K | A | G | K | T | L | A | V | T | L | A | K | A | G | W | R | V | A | L | I | E | Q | S | N | A | M | Y | G | G | T | C | I | N | I | G | C | I | P | T | K | T | L | V | H | D | A | Q | Q | H | T | D | F | V | R | A | I | Q | R | K | N | E | V | V | N | F | L | R | N | K |
Query Conservation |   |
|   |
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|   |
|   |   |
|   |
|
|
|
|   |   |   |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
L | S | . |
. |
V | G | V | I | G | A | G | P | A | G | L | A | A | A | E | E | L | R | A | K | G | Y | E | V | H | V | Y | D | R | Y | D | R | M | G | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | L | V | Y | G | I | P | G | F | K | L | E | K | S | V | V | E | R | R | V | K | L | L | A | D | A |
Template Known Secondary structure |   |
|
| . | . |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
| S | S | S | S |
| S | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  | T | S |
| T | T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|  | . | . |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
148 | . | |
|
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 |
  |
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | |
|
. | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | F | H | N | L | A | D | M | P | N | I | D | V | I | D | G | Q | A | E | F | I | N | N | H | S | L | R | V | H | R | P | E | G | N | L | E | I | H | G | E | K | I | F | I | N | T | G | A | Q | T | V | V | P | P | I | P | G | I | T | T | T | P | G | . |
. |
V | Y | D | S | T | G | L | L | N | L | K | E | L | P | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | V | I | Y | H | P | N | F | E | V | G | R | D | A | S | L | P | E | L | R | R | K | H | V | A | V | L | V | A | T | G | V | Y | K | A | R | D | I | K | A | P | G | S | G | L | G | N | I | V | A | A | L | D | Y | L | T | T | S | N | K | V | S | L | G | D | T | V | E | A | Y | E | N | G | S | L | N | A | A | G | K |
Template Known Secondary structure |   |
T |
|  |  |  | T | T |
|
| B | T | T | T | B |
|  |  |  |  |  | S | S |
| S |  |  |  |  |
|
|
|
|
|  |  |
|
| T | T |
| S |
|
| T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | T |
| S | S |
|
| T | T |
| S |
|
|
|
| S |
Template Predicted Secondary structure |   |
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
211 | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 |
  |
  |   |
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
H | L | G | I | L | G | G | G | Y | I | G | V | E | F | A | S | M | F | A | N | F | G | S | K | V | T | I | L | E | A | A | S | L | F | L | P | R | E | D | R | D | I | A | D | N | I | A | T | I | L | R | D | Q | G | V | D | I | I | L | N | A | H | V | E | R | I | S | H | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|   |
|   |
|   |
|   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
H | V | V | V | L | G | G | G | D | T | A | M | D | C | V | R | T | A | I | R | Q | G | A | T | S | V | K | C | L | Y | . |
. |
. |
R | R | D | R | K | N | M | P | G | S | Q | R | E | V | A | H | A | E | E | E | G | V | E | F | I | W | Q | A | A | P | E | G | F | T | G | D | T | V | V | T | G | V | R | A | V | R | I |
Template Known Secondary structure |   |
 |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |
| . | . | . | S | S |
| S | T | T |
| S | S |
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |
|
| S | S | S |
|
|  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  | . | . | . |  |
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
291 | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | |
|
|
. | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
229 | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | |
. | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
| . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | N | Q | V | Q | V | H | S | E | H | A | Q | L | A | V | D | A | L | L | I | A | S | G | R | Q | P | A | T | A | S | L | H | P | E | N | A | G | I | A | V | N | E | R | G | A | I | V | V | D | K | . |
R | L | H | T | T | A | D | N | I | W | A | M | G | D | V | T | G | G | L |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   | . |   |   |   |
|   |   |   |   |
|
|
|   |
|
|   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |   |
|   |   |   |
|
|
|
|   |
|
|   |
|   |
|   |
Template Sequence |   |
H | L | G | V | A | D | A | T | G | R | Q | T | P | Q | V | I | E | G | S | E | F | T | V | Q | A | D | L | V | I | K | A | L | G | F | E | P | E | D | L | P | N | A | F | D | E | P | E | L | K | V | T | R | W | G | T | L | L | V | D | H | R | T | K | M | T | N | M | D | G | V | F | A | A | G | D | I | V | R | G | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| S |  |  |  |  |
| S |
|  |  |
|
|
|  |  |  |  |  |  | S | T | T | S |
| B |
| T | T | S | S | B |
|
|
| T | T | T |
| B |
| S | S | T | T |  |  |  |
| G | G | G | G | S | S |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
368 | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . |
  |
  |   |
298 | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | F | T | Y | I | S | L | D | D | Y | R | I | V | R | D | E | L |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|
|   |   |
|   |   |
|
|   |   |
|
Template Sequence |   |
S | L | V | V | W | A | I | R | D | G | R | D | A | A | E | G | I |
Template Known Secondary structure |   |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
448 | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . |
  |