|   |
28 | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | E | R | A | L | N | A | S | Q | L | T | R | D | D | M | M | A | L | L | S | P | A | A | S | G | Y | L | E | Q | L | A | Q | R | A | Q | R | L | T | R | Q | R | F | G | N | T | V | S | F | Y | V | P | L | Y | L | S | N | L | C | A | N | D | C | T | Y | C | G | F | S | M | S | N | R | I | K | R | K | T | L | D | E |
Query Conservation |   |
|   |
|   |   |   |   |   |   |
|
|   |
|
|   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |
|
|   |
|   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | D | K | V | I | E | G | Y | Q | L | T | D | N | D | L | R | T | L | L | S | L | E | S | K | E | G | L | E | R | L | Y | S | A | A | R | K | V | R | D | H | Y | F | G | N | R | V | F | L | N | C | F | I | Y | F | S | T | Y | C | K | N | Q | C | S | F | C | Y | Y | N | C | R | N | E | I | N | R | Y | R | L | T | M |
Template Known Secondary structure |   |
 |  |  |  |  | T | T |
|
|
|
|  |  |  |  |  |  |  |  | T |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| T | T |
| T | T |
| T | T | S |
|
|
|
|
| B |
|
|  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
14 | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . |
  |
  |   |
108 | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | |
. | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | |
. | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | D | I | A | R | E | S | A | A | I | R | E | M | G | F | E | H | L | L | L | V | T | G | E | H | Q | A | K | V | . |
G | M | D | Y | F | R | R | H | L | P | A | L | R | E | Q | F | S | . |
S | L | Q | M | E | V | Q | P | L | A | E | T | E | Y | A | E | L | K | Q | L | G | L | D | G | V | M | V | Y | Q | E | T | Y |
Query Conservation |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |
|   |   |
|   |   |   | . |   |   |
|   |
|   |   |   |
|   |   |
|
|   |   |   |   | . |   |
|   |
|   |   |
|   |
|   |   |
|   |   |   |   |
|
|
|
|
|
|
|   |   |   |   |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|
|   |
Template Sequence |   |
E | E | I | K | E | T | C | K | T | L | K | G | A | G | F | H | M | V | D | L | T | M | G | E | D | P | Y | Y | Y | E | D | P | N | R | F | V | E | L | V | Q | I | V | K | E | E | L | G | L | P | I | M | I | S | P | G | L | M | D | N | A | T | L | L | K | A | R | E | K | G | A | N | F | L | A | L | Y | Q | E | T | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T | S |
|
| S |  |  |  |  |  |  |
|
|
|  |  |  |  |  | S | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S |
|  |  |  |  |
| S | S |
|
|  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |
|
|
| B |
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
94 | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . |
  |
  |   |
186 | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | E | A | T | Y | A | R | H | H | L | K | G | K | K | Q | D | F | F | W | R | L | E | T | P | D | R | L | G | R | A | G | I | D | K | I | G | L | G | A | L | I | G | L | S | D | N | W | R | V | D | S | Y | M | V | A | E | H | L | L | W | L | Q | Q | H | Y | W | Q | S | R | Y | S | V | S | F | P | R | L | R | P | C |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|   |
|   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   | . |   |
|   |   |   |   |
|   |
|
|   |
|   |   |   | . |
|   |   |   |   |
|   |   |
|   |   |
|   |   |   | . | . | . | . | . | . |   |   |   |
|   |   |   |   |
|   |
Template Sequence |   |
D | T | E | L | Y | R | K | L | R | V | G | . |
. |
. |
Q | S | F | D | G | R | V | N | A | R | R | F | A | K | Q | Q | G | Y | . |
C | V | E | D | G | I | L | T | G | V | G | N | D | I | E | . |
S | T | I | L | S | L | R | G | M | S | T | N | D | P | D | . |
. |
. |
. |
. |
. |
M | V | R | V | M | T | F | L | P | Q |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  | S | T | T | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| . |  |  |  |  |  |  |  |  | S | S | S |
|
|  |  | . |  |  |  |  |  |  |  |  |  |  |  | T |
|
| S | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|  |  |  |  |  |  |  |  |
|
|
|
|  |  | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
174 | . | . | . | . | . | 180 | . | . | . | . | |
|
|
. | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | |
. | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | |
. | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 240 | . | . |
  |
  |   |
266 | . | . | . | |
270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | |
. | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . |
Predicted Secondary structure |   |
|
|
|
| . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | G | G | I | . |
E | P | A | S | I | M | D | E | R | Q | L | V | Q | T | I | C | A | F | R | L | L | A | P | E | I | E | L | S | L | S | T | R | . |
E | S | P | W | F | R | D | R | V | I | P | L | A | I | N | N | V | S | A | F | S | K | T | Q | P | G | G | Y | A | D | N | H | P | E | L | E | Q | F | S | P | H | D |
Query Conservation |   |
  |
|
|   | . |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|
|   |
|
|   |
|
|   |   |   |
|   |   |
|
|   | . |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |
|
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | G | T | P | L | E | G | F | R | D | K | S | N | L | S | E | L | K | I | I | S | V | L | R | L | M | F | P | K | R | L | I | P | A | S | L | D | L | E | G | I | D | G | M | V | L | R | L | N | A | G | A | N | I | V | T | S | I | L | . |
. |
P | P | D | S | Q | L | E | G | V | A | N | Y | D | R | D | L | E | E | R |
Template Known Secondary structure |   |
T | T | S | T | T | T | T |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | S | T | T | S | B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |
| . | . |
| S | S |
|
|
|
|
| S | S |
| T | T | T | T |
| S | S |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
243 | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | |
|
. | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 |
  |
  |   |
344 | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | |
. | . | . | . | . | . | . | 370 |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  | . |  |
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Query Sequence |   |
D | R | R | P | E | A | V | A | A | A | L | T | A | Q | G | L | Q | P | V | . |
W | K | D | W | D | S | Y | L |
Query Conservation |   |
  |
|
|   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|
| . |   |
|
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | R | D | I | K | S | V | V | R | R | L | E | I | M | G | M | K | P | A | R | Q | A | D | F | E | A | V | L |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |
|
|  |  |  |  |  | T | T |
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
321 | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . |
  |