|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
60 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
Query Sequence |   |
D | K | T | I | A | F | S | L | L | D | L | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | I | P | E | G | S | S | A | R | E | A | F | S | H | S | L | D | L | A | R | L | A | E | K | R | G | Y | H | R | Y | W | L | A | E | H | H | N | M | T | G | I | A | S | A | A | . |
. |
. |
. |
. |
. |
T | S | V | L | I | G | Y |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|   |   |
|
|
|   |   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |
|   |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |
| . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |
Template Sequence |   |
R | K | H | I | H | F | G | V | L | I | Q | G | A | G | A | N | M | N | A | W | K | H | P | . |
S | V | P | P | D | A | S | V | N | F | D | F | Y | V | D | R | A | R | R | A | E | N | A | G | I | A | F | A | F | I | A | D | S | A | Y | V | T | P | K | S | A | P | H | F | L | N | R | F | E | P | I | S | L | L | S | A |
Template Known Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
| T | T |
| S | S | T | T | G | G | G | S | T | . | T | S |
| T | T | G | G | G |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
|
|
|
|
|
|
| T | T | S |
|  |  |  |  | S |
|
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | |
. | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
  |
  |   |
67 | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | |
|
|
. | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | A | A | N | T | T | T | L | H | L | G | S | G | G | V | M | L | P | N | H | S | P | L | V | I | A | E | Q | F | G | T | L | N | T | L | Y | P | G | R | I | D | L | G | L | G | R | A | P | G | S | D | Q | R | T | M | M | A | L | R | R | H | M | . |
. |
. |
S | G | D | I | D | N | F | P | R | D | V | A | E | L | V |
Query Conservation |   |
|
|   |   |
|   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|
|
|
|   |
|
|   |
|
|   |   |
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |
|   |
|
|
|
|
|
|   |
|   | . |   |   |   |   |   |
|   |   |
|
|   |   |   |
|
|
|
|   |
|
|   |
|
|   |   |
|
|
|
|   | . | . |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|
|
Template Sequence |   |
L | A | V | L | T | S | K | I | G | L | V | G | T | M | S | . |
S | S | Y | S | E | P | Y | N | V | A | R | Q | F | A | S | L | D | L | I | S | G | G | R | A | G | W | N | V | V | T | . |
. |
S | S | I | E | G | T | G | K | N | Y | G | R | P | H | P | D | H | A | Q | R | Y | A | I | A | A | E | H | L | D | V | V | Q |
Template Known Secondary structure |   |
 |  | T | T |
| S | S |
|  |  |  |  |  |  |  | . | S | S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  | S | . | . | S |
|
| T | T | G | G | G | G | T | T |
| S | S |
|
| S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |
| . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
| . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | |
. | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | |
|
. | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
  |
  |   |
144 | . | . | . | . | . | 150 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | W | F | D | A | R | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | N | P | H | V | R | P | V | P | G | Y | G | E | K | I | P | V | W | L | L | G | S | S | L | Y | S | A | Q | L | A | A | Q | L | G | L | P | F | A | F | A | S | H | F |
Query Conservation |   |
  |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|   |   |
|   |   |
|   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
G | L | W | D | S | W | D | D | D | A | L | V | R | D | R | A | T | G | R | F | F | D | P | D | K | L | H | R | L | D | H | R | G | R | F | F | S | V | E | G | P | L | N | I | R | R | S | P | Q | G | Q | P | V | I | F | Q | A | G | S | S | D | D | G | I | D | L | A | G | R | S | A | D | A | V | F | S | N | G | S | T |
Template Known Secondary structure |   |
 |  |  | T | S | B |
| T | T |
|
|
|
| B | T | T | T | T | B |
|
|
| G | G | G | B |
|
|
|
|  |  |
| S | S |
|  |  |
|
|
|
| S | S |
|
| B | T | T | B | S |
|  |  |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  |  |
| S |  |  |  |  |
|
| S | S |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
  |
  |   |
194 | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | P | D | M | L | F | Q | A | L | H | L | Y | R | S | N | F | K | P | S | A | R | L | E | K | P | Y | A | M | V | C | I | N | I | I | A | A | D | S | N | R | D | A | E | F | L | F | T | S | M | Q | Q | A | F | V | K | L | R | R | G | E | T | G | Q | L | P | P | P | I | Q | N | M | D | Q | F | W | S | P | S | E | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | D | E | A | R | V | F | Y | R | R | V | K | A | A | A | A | A | A | G | R | N | P | D | H | V | K | V | F | P | G | I | G | P | I | V | G | A | T | Q | Q | E | A | D | D | K | Y | R | Q | V | R | D | L | L | . |
. |
. |
. |
. |
S | P | R | E | A | L | A | Y | L | S | H | F | F | Q | Q | H | D | F | S | V | L | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| G | G | G | S |  |  |  |  |  |  |
|
|  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
| T | T |
|
|  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
239 | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . |
  |
  |   |
274 | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | |
. | . | 330 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Query Sequence |   |
Y | G | V | Q | Q | A | L | S | M | S | L | V | G | D | K | A | K | V | R | H | G | L | Q | S | I | L | R | E | T | D | A | D | E | I | M | V | N | G | Q | I | F | D | H | Q | A | R | L | H | S | F | E | L | A | M | . |
D | V | K | E | E | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
| . |
|   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|   |
|   |   |   |   |
|
|   |
|
|
|   |   |   |
|   |   |   |   |   |   | . | . | . | . | . |   |   |
|   |   |   |   |   |   |
|
|
|   |
|
Template Sequence |   |
E | V | A | Y | E | G | T | S | E | A | F | I | G | T | P | E | A | V | A | S | E | M | I | R | W | V | D | E | G | A | A | D | G | F | M | L | G | L | P | V | T | G | . |
. |
. |
. |
. |
F | G | L | D | D | F | V | D | H | V | L | P | V | L |
Template Known Secondary structure |   |
 |  |  |  |
|
|
| T | T | T | T |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| S |  |  |  |  |
|
| S | S | T | T | . | . | . | . | . |  |  |  |  |  |  |  |  |  | T |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
349 | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 400 | . | . | . | . |
  |