|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
60 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
D | K | T | I | A | F | S | L | L | D | L | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
P | I | P | E | G | S | S | A | R | E | A | F | S | H | S | L | D | L | A | R | L | A | E | K | R | G | Y | H | R | Y | W | L | A | E | H | H | N | M | T | G | I | A | S | A | A | . |
. |
. |
. |
. |
. |
T | S | V | L | I | G | Y | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|   |   |
|
|
|   |   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |
|   |   |   |
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |
|
|   |
|
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|
|
|
Template Sequence |   |
A | D | F | I | Q | F | G | A | M | I | H | G | V | G | G | T | T | D | G | W | R | H | P | D | V | D | P | S | A | S | T | N | I | E | F | Y | M | K | K | A | Q | T | A | E | K | G | L | F | S | F | I | F | I | A | D | G | L | F | I | S | E | K | S | I | P | H | F | L | N | R | F | E | P | I | T | I | L | S | A | L |
Template Known Secondary structure |   |
| S |
|
|  |  |  |  |  |
|
| T | T |
| S | S | S | S | G | G | G | S | T | T |
|
| T | T | G | G | G |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |
|
|
| S |
|
|
| T | T | S |
|  |  |  |  | S |
|
|
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . |
  |
  |   |
68 | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | |
|
|
|
. | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
| . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | N | T | T | T | L | H | L | G | S | G | G | V | M | L | P | N | H | S | P | L | V | I | A | E | Q | F | G | T | L | N | T | L | Y | P | G | R | I | D | L | G | L | G | R | A | P | G | S | D | Q | R | T | M | M | A | L | R | . |
. |
. |
. |
R | H | M | S | G | D | I | D | N | F | P | R | D | V | A | E | L | V |
Query Conservation |   |
|   |   |
|   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|
|
|
|   |
|
|   |
|
|   |   |
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|   |
|
|
|
|
|   |   |
|   | . |   |
|   |   |   |
|   |   |
|
|
|   |   |
|
|
|
|   |
|
|   |
|
|   |   |
|
|
|
|   | . | . |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|
|
Template Sequence |   |
A | S | V | T | K | N | I | G | L | V | G | T | F | S | . |
T | S | F | T | E | P | F | T | I | S | R | Q | L | M | S | L | D | H | I | S | G | G | R | A | G | W | N | L | V | T | . |
. |
S | P | Q | E | G | A | A | R | N | H | S | K | S | N | L | P | E | H | T | E | R | Y | E | I | A | Q | E | H | L | D | V | V | R |
Template Known Secondary structure |   |
 | T | T |
| S | S |
|  |  |  |  |  |  |  | . | T | T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  | S | . | . |
|
|
|  |  |  |  | T | T | T | T |
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |  |  |  | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
| . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
84 | . | . | . | . | . | 90 | . | . | . | . | . | . | . | |
. | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | |
|
. | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
  |
  |   |
144 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | W | F | D | A | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | P | N | P | H | V | R | P | V | P | G | Y | G | E | K | I | P | V | W | L | L | G | S | S | L | Y | S | A | Q | L | A | A | Q | L | G | L | P | F | A | F | A | S | H |
Query Conservation |   |
  |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   | . |   |   |
|
|
|   |   |
|   |   |
|
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
G | L | W | N | S | W | E | H | D | A | F | I | H | N | K | K | T | G | Q | F | F | D | Q | A | K | L | H | R | L | N | H | K | G | K | Y | F | Q | V | E | G | P | L | N | I | G | R | S | K | Q | . |
G | E | P | V | V | F | Q | A | G | S | S | E | T | G | R | Q | F | A | A | K | N | A | D | A | I | F | T | H | S | N |
Template Known Secondary structure |   |
 |  |  | T | S | B |
| T | T |
|
|
|
| B | T | T | T | T | B |
| S |
| G | G | G | B |
|
|
|
|  |  |
| S | S |
|  |  |
|
|
|
| S | S |
|
| B | T | T | . | B | S |
|  |  |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  |  |
| S |  |  |  |  |
|
| S |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | |
210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . |
  |
  |   |
193 | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | A | P | D | M | L | F | Q | A | L | H | L | Y | R | S | N | F | K | P | S | A | R | L | E | K | P | Y | A | M | V | C | I | N | I | I | A | A | D | S | N | R | D | A | E | F | L | F | T | S | M | Q | Q | A | F | V | K | L | R | R | G | E | T | G | Q | L | P | P | P | I | Q | N | M | D | Q | F | W | S | P | S | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |
Template Sequence |   |
S | L | E | E | T | K | A | F | Y | A | D | V | K | S | R | A | A | D | E | G | R | D | P | S | S | V | R | I | F | P | G | I | S | P | I | V | A | D | T | E | E | E | A | E | K | K | Y | R | E | F | A | E | L | I | P | I | E | N | A | V | T | E | A | K | A | R | N | . |
. |
. |
. |
. |
. |
. |
. |
L | T | L | R | E |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| G | G | G | S |  |  |  |  |  |  |
|
|  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| G | G | G | G |
|
|
|
|
|
| S |
| . | . | . | . | . | . | . | . |
|
|  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . |
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | 310 | . |
  |
  |   |
273 | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | |
. | . | 330 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Query Sequence |   |
Q | Y | G | V | Q | Q | A | L | S | M | S | L | V | G | D | K | A | K | V | R | H | G | L | Q | S | I | L | R | E | T | D | A | D | E | I | M | V | N | G | Q | I | F | D | H | Q | A | R | L | H | S | F | E | L | A | M | . |
D | V | K | E | E | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
| . |
|   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |
|   |   |
|
|   |   |
|   |
|   |
|
Template Sequence |   |
V | A | Q | E | M | A | F | P | R | T | L | F | I | G | T | P | E | R | V | A | S | L | I | E | T | W | F | N | A | E | A | A | D | G | F | I | V | G | S | D | I | P | G | . |
. |
. |
. |
. |
. |
T | L | D | A | F | V | E | K | V | I | P | I | L |
Template Known Secondary structure |   |
 |  |  |  |  |  | S |
|
|
| S | S |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| S |  |  |  |  |
|
|
| S | T | T | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
352 | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | |
|
|
|
|
|
. | . | . | . | . | 400 | . | . | . | . | . | . | . |
  |