Job Description P21599 Confidence 100.00% Date Thu Jan 5 11:38:29 GMT 2012 Rank 3 Aligned Residues 474 % Identity 37% Template c1t5aB_ PDB info PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase, m2 isozyme; PDBTitle: human pyruvate kinase m2 Resolution 2.80 Å

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		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.							.	.	.	.	.	.	.	70	.	.	.	.
Predicted Secondary structure																																																																.	.	.	.	.	.
Query SS confidence																																																																.	.	.	.	.	.
Query Sequence		M	S	R	R	L	R	R	T	K	I	V	T	T	L	G	P	A	T	D	R	D	N	N	L	E	K	V	I	A	A	G	A	N	V	V	R	M	N	F	S	H	G	S	P	E	D	H	K	M	R	A	D	K	V	R	E	I	A	A	K	L	G	.	.	.	.	.	.	R	H	V	A	I	L	G	D	L	Q	G	P
Query Conservation																																																																.	.	.	.	.	.
Alig confidence																																																																.	.	.	.	.	.
Template Conservation
Template Sequence		P	P	I	T	A	R	N	T	G	I	I	C	T	I	G	P	A	S	R	S	V	E	T	L	K	E	M	I	K	S	G	M	N	V	A	R	L	N	F	S	H	G	T	H	E	Y	H	A	E	T	I	K	N	V	R	T	A	T	E	S	F	A	S	D	P	I	L	Y	R	P	V	A	V	A	L	D	T	K	G	P
Template Known Secondary structure					S				S								T	T	T													T								T	T	S	S																		T	T	T	T		T	T	T													S
Template Predicted Secondary structure
Template SS confidence
		38	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.
		75	.	.	.	.	80	.	.	.	.				.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.		.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150
Predicted Secondary structure												.	.	.																		.
Query SS confidence												.	.	.																		.
Query Sequence		K	I	R	V	S	T	F	K	E	G	.	.	.	K	V	F	L	N	I	G	D	K	F	L	L	D	A	N	L	G	.	K	G	E	G	D	K	E	K	V	G	I	D	Y	K	G	L	P	A	D	V	V	P	G	D	I	L	L	L	D	D	G	R	V	Q	L	K	V	L	E	V	Q	G	M	K	V	F	T	E	V
Query Conservation												.	.	.																		.
Alig confidence												.	.	.																		.
Template Conservation
Template Sequence		E	I	R	T	G	L	I	K	G	S	G	T	A	E	V	E	L	K	K	G	A	T	L	K	I	T	L	D	N	A	Y	M	E	K	C	D	E	N	I	L	W	L	D	Y	K	N	I	C	K	V	V	E	V	G	S	K	I	Y	V	D	D	G	L	I	S	L	Q	V	K	Q	K	G	A	D	F	L	V	T	E	V
Template Known Secondary structure					B			B	S	S	S	S	S							T	T									G	G	G	T	T		B	B	T	T				B	S		S	G	G	G	G	T			T	T						T	T	T	T										S	S
Template Predicted Secondary structure
Template SS confidence
		118	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.
		151	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230
Predicted Secondary structure
Query SS confidence
Query Sequence		T	V	G	G	P	L	S	N	N	K	G	I	N	K	L	G	G	G	L	S	A	E	A	L	T	E	K	D	K	A	D	I	K	T	A	A	L	I	G	V	D	Y	L	A	V	S	F	P	R	C	G	E	D	L	N	Y	A	R	R	L	A	R	D	A	G	C	D	A	K	I	V	A	K	V	E	R	A	E	A	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	N	G	G	S	L	G	S	K	K	G	V	N	L	P	G	A	A	V	D	L	P	A	V	S	E	K	D	I	Q	D	L	K	F	G	V	E	Q	D	V	D	M	V	F	A	S	F	I	R	K	A	S	D	V	H	E	V	R	K	V	L	G	E	K	G	K	N	I	K	I	I	S	K	I	E	N	H	E	G	V
Template Known Secondary structure									S	S						S	S							S	S														T	T		S					T	T			S												T	G	G	G	T	T	S								S
Template Predicted Secondary structure
Template SS confidence
		198	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.
		231	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310
Predicted Secondary structure
Query SS confidence
Query Sequence		C	S	Q	D	A	M	D	D	I	I	L	A	S	D	V	V	M	V	A	R	G	D	L	G	V	E	I	G	D	P	E	L	V	G	I	Q	K	A	L	I	R	R	A	R	Q	L	N	R	A	V	I	T	A	T	Q	M	M	E	S	M	I	T	N	P	M	P	T	R	A	E	V	M	D	V	A	N	A	V	L	D
Query Conservation
Alig confidence		.	.	.
Template Conservation		.	.	.
Template Sequence		.	.	.	R	R	F	D	E	I	L	E	A	S	D	G	I	M	V	A	R	G	D	L	G	I	E	I	P	A	E	K	V	F	L	A	Q	K	M	M	I	G	R	C	N	R	A	G	K	P	V	I	C	A	T	Q	M	L	E	S	M	I	K	K	P	R	P	T	R	A	E	G	S	D	V	A	N	A	V	L	D
Template Known Secondary structure		.	.	.		T								S	S													S		G	G	G																T							S	S	T	T	G	G	G	G	T		S	S
Template Predicted Secondary structure		.	.	.
Template SS confidence
					278	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.
		311	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.				.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.
Predicted Secondary structure																																																.	.	.
Query SS confidence																																																.	.	.
Query Sequence		G	T	D	A	V	M	L	S	A	E	T	A	A	G	Q	Y	P	S	E	T	V	A	A	M	A	R	V	C	L	G	A	E	K	I	P	S	I	N	V	S	K	H	R	L	D	V	.	.	.	Q	F	D	N	V	E	E	A	I	A	M	S	A	M	Y	A	A	N	H	L	K	G	V	T	A	I	I	T	M	T	E
Query Conservation																																																.	.	.
Alig confidence																																																.	.	.																							.
Template Conservation																																																																									.
Template Sequence		G	A	D	C	I	M	L	S	G	E	T	A	K	G	D	Y	P	L	E	A	V	R	M	Q	N	L	I	A	R	E	A	E	A	A	I	Y	H	L	Q	L	F	E	E	L	R	R	L	A	P	I	T	S	D	P	T	E	A	T	A	V	G	A	V	E	A	S	F	K	C	C	S	.	G	A	I	I	V	L	T	K
Template Known Secondary structure		T		S					S					T		S																				S													S																						T		.	S							S
Template Predicted Secondary structure																																																																									.
Template SS confidence
		355	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.		.	.	.	.	430	.	.	.
		388	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430							.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.
Predicted Secondary structure																																													.	.	.	.	.	.
Query SS confidence																																													.	.	.	.	.	.
Query Sequence		S	G	R	T	A	L	M	T	S	R	I	S	S	G	L	P	I	F	A	M	S	R	H	E	R	T	L	N	L	T	A	L	Y	R	G	V	T	P	V	H	F	D	S	.	.	.	.	.	.	A	N	D	G	V	A	A	A	S	E	A	V	N	L	L	R	D	K	G	Y	L	M	S	G	D	L	V	I	V	T	Q
Query Conservation																																													.	.	.	.	.	.
Alig confidence																																													.	.	.	.	.	.
Template Conservation
Template Sequence		S	G	R	S	A	H	Q	V	A	R	Y	R	P	R	A	P	I	I	A	V	T	R	N	P	Q	T	A	R	Q	A	H	L	Y	R	G	I	F	P	V	L	C	K	D	P	V	Q	E	A	W	A	E	D	V	D	L	R	V	N	F	A	M	N	V	G	K	A	R	G	F	F	K	K	G	D	V	V	I	V	L	T
Template Known Secondary structure		S	S								T	T			S	S							S								G	G	G	S	T	T								S				S	S																				T	S			S	S
Template Predicted Secondary structure
Template SS confidence
		434	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.
		462	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	D	V	M	S	T	V	G	S	T	N	T	T	R	I	L	T	V
Query Conservation
Alig confidence							.
Template Conservation							.
Template Sequence		G	W	R	P	G	.	S	G	F	T	N	T	M	R	V	V	P	V
Template Known Secondary structure			S	S	S	S	.	S	S
Template Predicted Secondary structure							.
Template SS confidence
		514	.	.	.	.		.	520	.	.	.	.	.	.	.	.	.	530