Job Description P17952 Confidence 100.00% Date Thu Jan 5 11:36:25 GMT 2012 Rank 16 Aligned Residues 353 % Identity 19% Template c3n2aA_ PDB info PDB header:ligase Chain: A: PDB Molecule:bifunctional folylpolyglutamate synthase/dihydrofolate PDBTitle: crystal structure of bifunctional folylpolyglutamate2 synthase/dihydrofolate synthase from yersinia pestis co92 Resolution 1.90 Å

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		85	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.										.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.
Predicted Secondary structure																						.	.	.	.	.	.	.	.	.
Query SS confidence																						.	.	.	.	.	.	.	.	.
Query Sequence		S	S	A	I	S	A	D	N	P	E	I	V	A	A	H	E	A	R	I	P	.	.	.	.	.	.	.	.	.	V	I	R	R	A	E	M	L	A	E	L	M	R	F	R	H	G	I	A	I	A	G	T	H	G	K	T	T	T	T	A	M	V	S	S	I	Y	A	E	A	G	L	D	P	T	F	V	N	G	G	L
Query Conservation																						.	.	.	.	.	.	.	.	.
Alig confidence																						.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		T	P	Q	A	T	S	P	L	A	A	W	L	C	Y	L	E	H	L	H	S	Q	P	I	E	L	G	L	E	R	V	K	Q	V	A	E	R	L	D	L	L	K	P	A	P	K	I	F	T	V	A	G	T	N	G	K	G	T	T	C	C	T	L	E	A	I	L	L	A	A	G	L	R	V	G	V	Y	S	S	P	H
Template Known Secondary structure					T	T	S											T				T	T	S		S	S	S											T		S		S	S	S								S	S																T	T									S
Template Predicted Secondary structure
Template SS confidence
		6	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.
		156	.	.	.	160	.	.	.	.	.																																											.	.	.	.	170	.	.	.	.	.	.	.	.	.	180			.	.	.	.	.	.	.	.	.	190	.
Predicted Secondary structure												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																.	.
Query SS confidence												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																.	.
Query Sequence		V	K	A	A	G	V	H	A	R	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	H	G	R	Y	L	I	A	E	A	D	E	S	D	A	.	.	S	F	L	H	L	Q	P	M	V	A	I
Query Conservation												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																.	.
Alig confidence												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																.	.
Template Conservation
Template Sequence		L	L	R	Y	T	E	R	V	R	I	Q	G	Q	E	L	S	E	A	E	H	S	H	S	F	A	Q	I	E	A	G	R	G	D	I	S	L	T	Y	F	E	F	G	T	L	S	A	L	Q	L	F	K	Q	A	K	L	D	V	V	I	L	E	V	G	L	G	G	R	L	D	A	T	N	I	V	D	S	D	V	A	A
Template Known Secondary structure		S	S		G	G	G	G				T	T																				T	T																				T	T		S							S	S	S	S	T	T	S	G	G	G	G	S			S
Template Predicted Secondary structure
Template SS confidence
		86	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.
		192	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	T	N	I	E	A	D	H	M	D	T	Y	Q	G	D	F	E	N	L	K	Q	T	F	I	N	F	L	H	N	L	P	F	Y	G	R	A	V	M	C	V	D	D	P	V	I	R	E	L	L	P	R	V	G	R	Q	T	T	T	Y	G	F	S	E	D	A	D	V	R	V	E	D	Y	Q	Q	I	G	P	Q	G	H
Query Conservation
Alig confidence																													.	.	.																																																		.
Template Conservation																													.	.	.																																																		.
Template Sequence		I	T	S	I	A	L	D	H	T	D	W	L	G	Y	D	R	E	S	I	G	R	E	K	A	G	V	F	.	.	.	R	G	G	K	P	A	V	V	G	E	P	D	M	P	Q	S	I	A	D	V	A	A	E	L	G	A	Q	L	Y	R	R	D	V	A	W	K	F	S	Q	N	G	W	H	W	Q	C	G	E	R	.
Template Known Secondary structure									S	S			T	T		S										T	T		.	.	.		T	T	S							S	S													T						B	T	T	T													T	T		.
Template Predicted Secondary structure																													.	.	.																																																		.
Template SS confidence
		166	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.				.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.
		272	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	T	L	L	R	Q	D	K	E	P	M	R	V	T	L	N	A	P	G	R	H	N	A	L	N	A	A	A	A	V	A	V	A	T	E	E	G	I	D	D	E	A	I	L	R	A	L	E	S	F	Q	G	T	G	R	R	F	D	F	L	G	E	F	P	L	E	P	V	N	G	K	S	G	T	A	M	L	V	D	D
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.																																																		.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.																																																		.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	Q	L	T	G	L	P	V	P	N	V	P	L	A	N	A	A	T	A	L	A	V	L	H	Y	S	E	L	P	L	S	D	E	A	I	R	Q	G	L	Q	A	A	S	L	P	G	R	F	Q	V	.	.	.	.	.	.	.	.	.	.	V	S	E	Q	P	L	L	I	L	D
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.									S	S																T																		T	T	S	S			.	.	.	.	.	.	.	.	.	.			T	T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.																																																		.	.	.	.	.	.	.	.	.	.
Template SS confidence
													256	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.											.	.	.	.	.	310	.	.	.	.
		352	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	G	H	H	P	T	E	V	D	A	T	I	K	A	A	R	A	G	W	P	D	K	N	L	V	M	L	F	Q	P	H	R	F	T	R	T	R	D	L	Y	D	D	F	A	N	V	L	T	Q	V	D	T	L	L	M	L	E	V	Y	P	A	G	E	A	P	I	P	G	A	D	S	R	S	L	C	R	T	I	R	G
Query Conservation
Alig confidence																			.	.	.																						.	.	.																			.	.	.	.	.												.	.
Template Conservation																			.	.	.																						.	.	.																			.	.	.	.	.												.	.
Template Sequence		V	A	H	N	P	H	A	A	R	Y	L	V	N	R	L	A	Q	.	.	.	V	G	K	V	R	A	V	V	G	M	L	S	D	K	D	I	A	G	T	L	A	.	.	.	C	L	S	E	R	V	D	E	W	Y	C	A	P	L	E	G	P	R	.	.	.	.	.	G	A	S	A	G	Q	L	A	E	H	L	.	.
Template Known Secondary structure					S													T	.	.	.											B	T	T	S								.	.	.			T	T	T		S									T	T	T	.	.	.	.	.	B								T	T		.	.
Template Predicted Secondary structure																			.	.	.																						.	.	.																			.	.	.	.	.												.	.
Template SS confidence
		315	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.				.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.				.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370						.	.	.	.	.	.	.	.	.	380	.
		432	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Predicted Secondary structure
Query SS confidence
Query Sequence		R	G	K	I	D	P	I	L	V	P	D	P	A	R	V	A	E	M	L	A	P	V	L	T	G	N	D	L	I	L	V	Q	G	A	G	N	I	G	K	I	A	R	S	L	A	E	I	K	L
Query Conservation
Alig confidence		.	.	.																														.	.
Template Conservation		.	.	.																														.	.
Template Sequence		.	.	.	V	S	A	R	Q	F	S	D	V	E	T	A	W	R	Q	A	M	Q	D	A	D	T	Q	D	V	V	I	V	C	.	.	G	S	F	H	T	V	A	H	V	M	A	A	L	H	L
Template Known Secondary structure		.	.	.	S	S					S	S														T	T							.	.	S	S												T
Template Predicted Secondary structure		.	.	.																														.	.
Template SS confidence
					391	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.			420	.	.	.	.	.	.	.	.	.	430	.	.	.	.