Job Description P17952 Confidence 100.00% Date Thu Jan 5 11:36:25 GMT 2012 Rank 9 Aligned Residues 368 % Identity 17% Template c2vosA_ PDB info PDB header:ligase Chain: A: PDB Molecule:folylpolyglutamate synthase protein folc; PDBTitle: mycobacterium tuberculosis folylpolyglutamate synthase2 complexed with adp Resolution 2.0 Å

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		94	.	.	.	.	.	100	.	.	.		.	.	.	.	.	.	110	.	.	.	.	.	.					.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.
Predicted Secondary structure												.														.	.	.	.
Query SS confidence												.														.	.	.	.
Query Sequence		E	I	V	A	A	H	E	A	R	I	.	P	V	I	R	R	A	E	M	L	A	E	L	M	.	.	.	.	R	F	R	H	G	I	A	I	A	G	T	H	G	K	T	T	T	T	A	M	V	S	S	I	Y	A	E	A	G	L	D	P	T	F	V	N	G	G	L	V	K	A	A	G	V	H	A	R	L	G	H	G
Query Conservation												.														.	.	.	.
Alig confidence												.														.	.	.	.
Template Conservation
Template Sequence		E	H	L	L	D	Q	R	W	R	I	D	P	S	L	T	R	I	S	A	L	X	D	L	L	G	S	P	Q	R	S	Y	P	S	I	H	I	A	G	T	N	G	K	T	S	V	A	R	X	V	D	A	L	V	T	A	L	H	R	R	T	G	R	T	T	S	P	H	L	Q	S	P	V	E	R	I	S	I	D	G	K
Template Known Secondary structure						T	T	T					T	T											T	T		G	G	G	S	S								S	S	S															T	T								S	S		S	S		G	G	G	G				T	T
Template Predicted Secondary structure
Template SS confidence
		33	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.
																																																				169	170	.	.	.	.	.	.	.	.	.	180			.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.													.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.													.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	R	Y	L	I	A	E	A	D	E	S	D	A	.	.	S	F	L	H	L	Q	P	M	V	A	I	V	T	N	I	E
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.													.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.													.	.
Template Conservation
Template Sequence		P	I	S	P	A	Q	Y	V	A	T	Y	R	E	I	E	P	L	V	A	L	I	D	Q	Q	S	Q	A	S	P	A	X	S	K	F	E	V	L	T	A	X	A	F	A	A	F	A	D	A	P	V	D	V	A	V	V	E	V	G	X	G	G	R	W	D	A	T	N	V	I	N	A	P	V	A	V	I	T	P	I	S
Template Known Secondary structure																																																	T	T		S							S	S	S	S	T	T	S	T	T		S	S			S
Template Predicted Secondary structure
Template SS confidence
		116	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.
		197	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.		.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.
Predicted Secondary structure																													.
Query SS confidence																													.
Query Sequence		A	D	H	M	D	T	Y	Q	G	D	F	E	N	L	K	Q	T	F	I	N	F	L	H	N	L	P	F	.	Y	G	R	A	V	M	C	V	D	D	P	V	I	R	E	L	L	P	R	V	G	R	Q	T	T	T	Y	G	F	S	E	D	A	D	V	R	V	E	D	Y	Q	Q	I	G	P	Q	G	H	F	T	L	L
Query Conservation																													.
Alig confidence																													.
Template Conservation
Template Sequence		I	D	H	V	D	Y	L	G	A	D	I	A	G	I	A	G	E	K	A	G	I	I	T	R	A	P	S	P	D	T	V	A	V	I	G	R	Q	V	P	K	V	X	E	V	L	L	A	E	S	V	R	A	D	A	S	V	A	R	E	D	S	E	F	A	V	L	R	R	Q	I	A	V	G	G	Q	V	L	Q	L	Q
Template Known Secondary structure				B		S		S	S												T	T																															T	T						B	T	T	T	B									T	T
Template Predicted Secondary structure
Template SS confidence
		201	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
		276	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.				.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.
Predicted Secondary structure																																		.	.	.
Query SS confidence																																		.	.	.
Query Sequence		R	Q	D	K	E	P	M	R	V	T	L	N	A	P	G	R	H	N	A	L	N	A	A	A	A	V	A	V	A	T	E	E	.	.	.	G	I	D	D	E	A	I	L	R	A	L	E	S	F	Q	G	T	G	R	R	F	D	F	L	G	E	F	P	L	E	P	V	N	G	K	S	G	T	A	M	L	V	D	D	Y
Query Conservation																																		.	.	.
Alig confidence																																		.	.	.																.										.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																				.										.	.	.	.	.	.	.	.	.	.	.
Template Sequence		G	L	G	G	V	Y	S	D	I	Y	L	P	L	H	G	E	H	Q	A	H	N	A	V	L	A	L	A	S	V	E	A	F	F	G	A	Q	L	D	G	D	A	V	R	A	G	F	A	A	V	T	.	S	P	G	R	L	E	R	X	R	.	.	.	.	.	.	.	.	.	.	.	S	A	P	T	V	F	I	D	A
Template Known Secondary structure			T	T												S																		T	T														T			.		T	T	S	S					.	.	.	.	.	.	.	.	.	.	.	T	T	T
Template Predicted Secondary structure																																																				.										.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		283	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.		.	.	.	.	.	.	.	340	.												.	.	.	.	.	.	.	.	350
		353	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	H	H	P	T	E	V	D	A	T	I	K	A	A	R	A	G	W	P	D	K	N	L	V	M	L	F	Q	P	H	R	F	T	R	T	R	D	L	Y	D	D	F	A	N	V	L	T	Q	V	D	T	L	L	M	L	E	V	Y	P	A	G	E	A	P	I	P	G	A	D	S	R	S	L	C	R	T	I	R	G	R
Query Conservation
Alig confidence																																												.	.	.																	.	.	.	.	.
Template Conservation																																												.	.	.																	.	.	.	.	.
Template Sequence		A	H	N	P	A	G	A	S	A	L	A	Q	T	L	A	H	E	F	D	F	R	F	L	V	G	V	L	S	V	L	G	D	K	D	V	D	G	I	L	A	A	L	.	.	.	E	P	V	F	D	S	V	V	V	T	H	N	G	S	P	R	.	.	.	.	.	A	L	D	V	E	A	L	A	L	A	A	G	E	R
Template Known Secondary structure				S														S				S									B	T	T	B										.	.	.	T	T	T		S								S		T	T	.	.	.	.	.	B
Template Predicted Secondary structure																																												.	.	.																	.	.	.	.	.
Template SS confidence
		355	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.				.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.						.	.	.	.	.	.	.	420	.	.	.	.	.	.
		433	.	.		.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.										.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.
Predicted Secondary structure					.																					.	.	.	.	.	.	.	.	.
Query SS confidence					.																					.	.	.	.	.	.	.	.	.
Query Sequence		G	K	I	.	D	P	I	L	V	P	D	P	A	R	V	A	E	M	L	A	P	V	L	T	.	.	.	.	.	.	.	.	.	G	N	D	L	I	L	V	Q	G	A	G	N	I	G	K	I	A	R	S	L	A	E	I	K	L	K	P	Q
Query Conservation					.																					.	.	.	.	.	.	.	.	.
Alig confidence					.																					.	.	.	.	.	.	.	.	.								.	.
Template Conservation																																										.	.
Template Sequence		F	G	P	D	R	V	R	T	A	E	N	L	R	D	A	I	D	V	A	T	S	L	V	D	D	A	A	A	D	P	D	V	A	G	R	T	G	I	V	I	.	.	T	G	S	V	V	T	A	G	A	A	R	T	L	F	G	R	D	P	Q
Template Known Secondary structure				G	G	G					S	S																	T		T	T	T	T								.	.		S	S											T	T
Template Predicted Secondary structure																																										.	.
Template SS confidence
		427	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.			.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.