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Job DescriptionP24171
Confidence100.00%DateThu Jan 5 11:40:46 GMT 2012
Rank3Aligned Residues640
% Identity27%Templated1s4bp_
SCOP infoZincin-like Metalloproteases ("zincins"), catalytic domain Neurolysin-like
Resolution2.00

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   11........20.........30.........40.........50 .........60.........70.........80.........
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Query Sequence  STLPYLAPHFDQIANHHYRPAFDEGMQQKRAEIAAIALNP. QMPDFNNTILALEQSGELLTRVTSVFFAMTAAHTNDELQ
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Template Conservation 


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Template Sequence  WDL. . . . . . . . . . SAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQHVSPSKDIR
Template Known Secondary structure 


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T

GGG

TTTTS
S
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   26.. .30.........40.........50.........60.........70.........80.........90.....
 
   90.........100.........110.........120.........130.........140.........150.........160.........
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Query Sequence  RLDEQFSAELAELANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQRFVLAGAKLAQADKAKLKVLNTEAATLT
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Template Conservation           
      
     
   
           
  
        
      
  
     
    
      
 
Template Sequence  TASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLC
Template Known Secondary structure  T
S
TT
S
TTTTS
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   96...100.........110.........120.........130.........140.........150.........160.........170.....
 
   170.........180.........190.........200.........210.........220.........230.........240.........
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Query Sequence  SQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAEAAREKGLDNKWLIPLLNTTQQPALAEMRDRATREKLFIAGWTR
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Template Conservation    
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Template Sequence  IDFNKNLNEDTTFLPF. . . TLQELGGLPEDFLNSLEKM. . . . . EDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNSR
Template Known Secondary structure 


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TTTTTT

TTTTTSS
.....TTS
SS


TTT
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   176...180.........190. ........200.........210 .........220.........230.........240.......
 
   250.........260.........270.........280.........290.........300.........310.........320.......
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Query Sequence  AEKNDANDTRAIIQRLVEIRAQQATLLGFPHYAAWKIADQMAKTPEAALNFMREIVPAARQRASDELASIQAVIDKQQ. .
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Template Conservation      ....    
  
   
   
 
 

 
     
        
 
  

  
     
                   
Template Sequence  CKEE. . . . NSAILKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAECER
Template Known Secondary structure  T....TT
SSTTSTT
S
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   248.250. ........260.........270.........280.........290.........300.........310.........320...
 
   328.330.........340.........350.........360.........370.........380.........390.........400..
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Query Sequence  . . . . GGFSAQPWDWAFYAEQVRREKFDLDEAQLKPYFELNTVLNEGVFWTANQLFGIKFVERFDIPVYHPDVRVWEIFD.
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Template Conservation          
  

                      
     
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Template Sequence  RGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVT. HGLLGIYQELLGLAFHHEEGASAWHEDVRLYTARDA
Template Known Secondary structure  T



SS

TTTT


TT
B.T
TT


SSTT
T
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   324.....330.........340.........350.........360...... ...370.........380.........390.........400..
 
   403......410.........420.........430..... ....440.........450.........460.........470.........
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Query Sequence  HNGVGLALFYGDFFARDSKSGGAWMGNFVEQST. . . LNKTHPVIYNVCNYQKPAAGEPALLLWDDVITLFHEFGHTLHGL
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Template Conservation        
  


   
 

  

             
    
   
  

          
   

 

 

 


 
  
Template Sequence  ASGEVVGKFYLDLYPREGKYGHAACFGLQPGCLRQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQL
Template Known Secondary structure  TT


S

TTS
SS



TTS







BTTB

B

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   403......410.........420.........430.........440.........450.........460.........470.........480..
 
   480.........490.........500.........510.........520.........530.........540.........550.........
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Query Sequence  FARQRYATLSGTNTPRDFVEFPSQINEHWATHPQVFARYARHYQSGAAMPDELQQKMRNASLFNKGYEMSELLSAALLDM
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Template Conservation 

              
 

  
   
        
            
       
              
   
 

 
Template Sequence  CSQAEFAMFSGTHVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQIVLAKVDQ
Template Known Secondary structure 


SSGGGSTT
S
TTTTTGGGGST


TTT




GGGTT
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   483......490.........500.........510.........520.........530.........540.........550.........560..
 
   560.........570.........580.........590.........600.........610.........620........ .630........
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Query Sequence  RWHCLEENEAMQDVDDFELRALVAENMDLPAIPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADDGYQW. FVEQGGLTRE
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Template Conservation    
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Template Sequence  ALHTQTDAD. . . . . PAEEYARLCQEILGVPATPGTNMPATFGHLAG. GYDAQYYGYLWSEVYSMDMFHTRFKQEGVLNSK
Template Known Secondary structure  TT
SS

.....TTSS


TT

GGGG
GGGGT.T
TTTTTT
TT
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   563......570. ........580.........590.........600... ......610.........620.........630......
 
   639640.........650.........660.........670.........
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Query Sequence  NGLRFREAILSRGNSEDLERLYRQWRGKAPKIMPMLQHRGL
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Template Conservation   
       
  


  
 



 
 
  
   
     

Template Sequence  VGMDYRSCILRPGGSEDASAMLRRFLGRDPKQDAFLLSKGL
Template Known Secondary structure  TTTTGGGS
SS


STT
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   637..640.........650.........660.........670.......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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