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Job DescriptionP24171
Confidence100.00%DateThu Jan 5 11:40:46 GMT 2012
Rank2Aligned Residues653
% Identity24%Templated1i1ip_
SCOP infoZincin-like Metalloproteases ("zincins"), catalytic domain Neurolysin-like
Resolution2.30

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   8.10.........20.........30.........40.........50 .........60.........70.........80......
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Query Sequence  LVQSTLPYLAPHFDQIANHHYRPAFDEGMQQKRAEIAAIALNP. QMPDFNNTILALEQSGELLTRVTSVFFAMTAAHTND
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Template Conservation               




          
         
             
  
      
                 
Template Sequence  MSSYTAAGRNVLRWDLSPEQIKTRTEQLIAQTKQVYDTVGTIALKEVTYENCLQVLADIEVTYIVERTMLDFPQHVSSDR
Template Known Secondary structure 

TT

TTT



S


TTS
GGG

TTTTS
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   14.....20.........30.........40.........50.........60.........70.........80.........90...
 
   87..90.........100.........110.........120.........130.........140.........150.........160......
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Query Sequence  ELQRLDEQFSAELAELANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQRFVLAGAKLAQADKAKLKVLNTEAA
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Template Conservation       
             
     
   
           
  
        
      
  
          
     
Template Sequence  EVRAASTEADKKLSRFDIEMSMREDVFQRIVHLQETCDLEKIKPEARRYLEKSIKMGKRNGLHLSEHIRNEIKSMKKRMS
Template Known Secondary structure  T
S
TTSS
TTTTS
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   94.....100.........110.........120.........130.........140.........150.........160.........170...
 
   167..170.........180.........190.........200.........210.........220.........230.........240......
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Query Sequence  TLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAEAAREKGLDNKWLIPLLNTTQQPALAEMRDRATREKLFIAG
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Template Conservation   
   
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Template Sequence  ELCIDFNKNL. . . NEDDTSLVFSKAELGALPDDFIDSLEKT. . . . . DEDKYKVTLKYPHYFPVMKKCCVPETRRKMEMAF
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TGGGTT

TS
B
.....SSS
SS


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   174.....180... ......190.........200.........210. ........220.........230.........240.....
 
   247..250.........260.........270.........280.........290.........300.........310.........320......
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Query Sequence  WTRAEKNDANDTRAIIQRLVEIRAQQATLLGFPHYAAWKIADQMAKTPEAALNFMREIVPAARQRASDELASIQAVIDKQ
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Template Conservation         ....    
  
   
   
   
  
     
        
 
  

                 
       
Template Sequence  HTRCKQE. . . . NTAILQQLLPLRAQVAKLLGYNTHADFVLELNTAKSTSRVAAFLDDLSQKLKPLGEAEREFILSLKKKE
Template Known Secondary structure  TTTT....T
SSTTSTT
S
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   246...250.. .......260.........270.........280.........290.........300.........310.........320.
 
   327 ..330.........340.........350.........360.........370.........380.........390.........400
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Query Sequence  Q. . . . . . GGFSAQPWDWAFYAEQVRREKFDLDEAQLKPYFELNTVLNEGVFWTANQLFGIKFVERFDIPVYHPDVRVWEI
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Template Conservation             
  

                   
  
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Template Sequence  CEERGFEYDGKINAWDLHYYMTQTEELKYSVDQESLKEYFPIEVVT. EGLLSIYQELLGLSFEQVPDAHVWNKSVSLYTV
Template Known Secondary structure  TTT



SS

S


GGG
B.T
TT


SSTT
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   322.......330.........340.........350.........360....... ..370.........380.........390.........400
 
   401. .......410.........420.........430.... .....440.........450.........460.........470......
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Query Sequence  FD. HNGVGLALFYGDFFARDSKSGGAWMGNFVEQS. . . TLNKTHPVIYNVCNYQKPAAGEPALLLWDDVITLFHEFGHTL
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Template Sequence  KDKATGEVLGQFYLDLYPREGKYNHAACFGLQPGCLLPDGSRMMSVAALVVNFSQPVAGRPSLLRHDEVRTYFHEFGHVM
Template Known Secondary structure  TTT


S

TTS

S



B
TTS
B








TTS

B

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   401........410.........420.........430.........440.........450.........460.........470.........480
 
   477..480.........490.........500.........510.........520.........530.........540.........550......
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Query Sequence  HGLFARQRYATLSGTNTPRDFVEFPSQINEHWATHPQVFARYARHYQSGAAMPDELQQKMRNASLFNKGYEMSELLSAAL
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Template Conservation 
  

              
 

  
   
        
            
                      
   
 
Template Sequence  HQICAQTDFARFSGTNVETDFVEVPSQMLENWVWDVDSLRKLSKHYKDGHPITDELLEKLVASRLVNTGLLTLRQIVLSK
Template Known Secondary structure 


SSGGGSTT
S
TTTTGGGG



TTT




TTTTT
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   481........490.........500.........510.........520.........530.........540.........550.........560
 
   557..560.........570.........580.........590.........600.........610.........620...... ...630.....
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Query Sequence  LDMRWHCLEENEAMQDVDDFELRALVAENMDLPAIPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADDGY. QWFVEQGGL
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Template Conservation 

   
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Template Sequence  VDQSLHTNATLD. . . . . AASEYAKYCTEILGVAATPGTNMPATFGHLAG. GYDGQYYGYLWSEVFSMDMFHSCFKKEGIM
Template Known Secondary structure  TTT
SS

.....TSS


TT

GGGG
TTTSS.S
TT
TTT
TT
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   561........570.. .......580.........590.........600.... .....610.........620.........630....
 
   636...640.........650.........660.........670.........
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Query Sequence  TRENGLRFREAILSRGNSEDLERLYRQWRGKAPKIMPMLQHRGL
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Template Conservation              
  


  
 


  
 
  
   
     
 
Template Sequence  NPEVGMKYRNLILKPGGSLDGMDMLQNFLQREPNQKAFLMSRGL
Template Known Secondary structure 
TTTTTTSS
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ST
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   635....640.........650.........660.........670........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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