|   |
293 | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | P | E | A | A | L | N | F | M | R | E | I | V | P | A | A | R | Q | R | A | S | D | E | L | A | S | I | Q | A | V | I | D | K | Q | Q | G | G | F | S | A | Q | P | W | D | W | A | F | Y | A | E | Q | V | R | R | E | K | F | D | L | D | E | A | Q | L | K | P | Y | F | E | L | N | T | V | L | N | E | G | V | F | W |
Query Conservation |   |
  |
|
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|
|   |   |   |
|   |   |
|
|   |
|
|   |   |
|
|   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | P | T | Q | I | H | Q | I | G | L | D | E | V | A | R | I | S | G | V | M | N | E | . |
. |
. |
. |
. |
. |
. |
. |
I | L | L | A | Q | G | Y | T | K | G | T | V | G | E | R | M | V | A | L | N | E | E | P | R | F | L | Y | E | D | S | I | A | G | R | E | E | L | L | S | D | I | N | G | Y | I | T | E | V | T | A |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  | T | T |
|
| S | S |
|  |  |  |  |  |  |  |  |  | T | S | G | G | G |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
301 | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . |
  |
  |   |
373 | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | A | N | Q | L | F | G | I | K | F | V | E | R | F | D | I | P | V | Y | H | P | D | V | R | V | W | E | I | F | D | H | N | G | V | G | L | A | L | F | Y | G | D | F | F | A | R | D | S | K | S | G | G | A | W | M | G | N | F | V | E | Q | S | T | L | N | K | T | H | P | V | I | Y | N | V | C | N | Y | Q | K | P |
Query Conservation |   |
  |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |
|   |   |   |   |   | . | . | . | . | . | . |   |   |   |
|
|   |   |   |   |
Template Sequence |   |
K | M | A | P | V | F | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | T | P | S | Y | Q | V | E | V | K | S | F | P | V | E | V | Q | D | G | A | P | G | G | Q | Y | T | S | P | A | V | D | G | S | K | P | G | . |
. |
. |
. |
. |
. |
I | Y | W | I | N | L | R | D | M |
Template Known Secondary structure |   |
 | T | G | G | G |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
| S |
|
|  |  |  |  |  |
|
| T | T | T | T | T | T | S |
| S |  |  |  |  |
|
|
| T | T | S | S |
|
|  | . | . | . | . | . | . |  |  |  |  |
|
| S |
| G |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
373 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | |
|
|
|
|
|
. | . | . | . | 420 | . | . | . | . |
  |
  |   |
453 | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | |
|
. | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | |
|
. | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | G | E | P | A | L | L | L | W | D | D | V | I | T | L | F | H | E | F | . |
. |
G | H | T | L | H | G | L | F | A | R | Q | R | Y | A | T | . |
. |
L | S | G | T | N | T | P | R | D | F | V | E | F | P | S | Q | I | N | E | H | W | A | T | H | P | Q | V | F | A | R | Y | A | R | H | Y | Q | S | G | A | A | M |
Query Conservation |   |
  |   |   |   |   |   |
|
|   |   |   |
|
|   |
|
|   |
|
|
| . | . |
|
|
|   |
|   |   |
|
|   |   |   |   |   |   | . | . |   |   |
|   |   |   |   |   |
|   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |
|   |
|   |   |
Alig confidence |   |
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
  |   |   |   | . | . | . | . |   |   |   |
|   |   |   |   |   |
|
|   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |
|   |   |
|   |
|   | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
Template Sequence |   |
K | A | N | P | . |
. |
. |
. |
K | F | G | L | K | T | L | T | Y | H | E | A | N | P | G | H | H | W | Q | I | A | L | N | L | D | Q | A | E | L | P | F | L | R | R | I | A | P | Y | N | A | Y | T | E | G | W | A | L | Y | S | E | Q | V | A | Y | E | L | G | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | E | N | D |
Template Known Secondary structure |   |
G | G | S |
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | S | T | T | T |  |  |  |  |  |  |  |  |  | T |
| T | T | S |
|  |  |  |  | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | . | . | . | . | . | . | . | . | . | . | T | T | T |
|
Template Predicted Secondary structure |   |
|
|
|
| . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
425 | . | . | . | |
|
|
|
. | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | 490 |
  |
  |   |
529 | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | D | E | L | Q | Q | K | M | R | N | A | S | L | F | N | K | G | Y | E | M | S | E | L | L | S | A | A | L | L | D | M | R | W | H | C | L | E | E | N | E | A | M | Q | D | V | D | D | F | E | L | R | A | L | V | A | E | N | M | D | L | P | A | I | P | P | R | Y | R | S | S | Y | F | A | H | I | F | G | G | G | Y |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
| . |
|
|
Template Conservation |   |
|   |   |   |
|
|   |
|   |   | . | . | . | . | . | . | . | . | . |   |
|   |
|
|   |
|   |
|
|
|   |
|
|
| . | . | . | . | . | . | . |   |   |
|
|
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
| . | . | . | . |
|   | . |   |   |
Template Sequence |   |
P | F | G | D | L | G | R | L | Q | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
E | L | F | R | A | V | R | L | V | V | D | T | G | L | H | . |
. |
. |
. |
. |
. |
. |
D | K | R | W | T | R | E | Q | A | I | S | Y | M | S | E | Q | T | G | T | A | E | S | D | V | V | A | E | I | E | R | . |
. |
. |
. |
Y | M | . |
A | W |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  | . |  | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  | . |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
491 | . | . | . | . | . | . | . | . | 500 | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | |
|
|
|
. | . | |
. | . |
  |
  |   |
609 | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | |
|
. | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | G | Y | Y | A | Y | L | W | T | Q | M | L | A | D | D | G | Y | Q | W | F | V | E | Q | . |
. |
G | G | L | T | R | E | N | G | L | R | F | R | E | A | I | L | S | R | G | N |
Query Conservation |   |
  |   |   |
|
|   |
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |
|
|
| . | . | . |
|   |
|
|   |   |
|
|   |   |
|   |
Template Sequence |   |
P | G | Q | A | L | G | Y | K | L | G | M | L | K | I | L | S | L | R | E | Q | A | K | A | R | L | G | D | K | F | D | L | . |
. |
. |
A | E | F | H | D | V | V | L | L | N | G | A |
Template Known Secondary structure |   |
T | T | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G |
|
|  | . | . | . |  |  |  |  |  |  |  |  | T | T |
| S |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | |
|
|
. | . | . | . | . | . | . | . | . | 590 | . | . |
  |