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Job DescriptionP24171
Confidence100.00%DateThu Jan 5 11:40:46 GMT 2012
Rank9Aligned Residues545
% Identity12%Templatec2c6nA_
PDB info PDB header:hydrolase/hydrolase inhibitorChain: A: PDB Molecule:angiotensin-converting enzyme, somatic isoform; PDBTitle: structure of human somatic angiontensin-i converting enzyme n domain2 with lisinopril
Resolution3.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   4950.........60.........70.........80.........90.........100.........110.........120........
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Query Sequence  NPQMPDFNNTILALEQSGELLTRVTSVFFAMTAAHTNDELQRLDEQFSAELAELANDIYLNGELFARVDAVWQRRESLGL
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Template Sequence  SADEAGAQLFAQSYNSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWG. . . . . . QKAKELYEPIWQNFT
Template Known Secondary structure 
SSGGGS

......SSSTT

S
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   11........20.........30.........40.........50.........60......... 70.........80....
 
   129130.........140.........150.........160.........170.........180.........190.........200........
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Query Sequence  DSESIRLVEVIHQRFVLAGAKLAQADKAKLKVLNTEAATLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAEAA
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Template Sequence  DPQLRRIIGAV. . . RTLGSANLPLAKRQQYNALLSNMSRI. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . YSTAK
Template Known Secondary structure 
...S

TTTTS
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   85....90..... ....100.........110.........120. .....
 
   209210.........220.........230.........240.........250.........260.........270.........280........
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Query Sequence  REKGLDNKWLIPLLNTTQQPALAEMRDRATREKLFIAGWTRAEKNDANDTRAIIQRLVEIRAQQATLLGFPHYAAWKIAD
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Template Sequence  VCLPNKTATCWSLD. PDLTNILASSRSYAMLLFAWEGWHNAAGIP. . . . LKPLYEDFTALSNEAYKQDGFTDTGAYWRSW
Template Known Secondary structure 

SS




TT.T


....TTTT
SSTTT
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   127..130.........140 .........150.........160.........170 .........180.........190.........200.
 
   289290.........300.........310.........320.........330........ .340.........350.........360......
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Query Sequence  QMAKTPEAALNFMREIVPAARQRASDELASIQAVIDKQQGGFSAQPWDWA. . FYAEQVRREKFDLDEAQLKPYFELNTVL
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Template Sequence  . . . YNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLD
Template Known Secondary structure  ...T

TT
TTT

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TTSSSSTT
S

TTS
SS
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   202.......210.........220.........230.........240.........250.........260.........270........
 
   367..370.........380.........390.........400.........410.........420.........430.........440......
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Query Sequence  NEGVFWTANQLFGIKFVERFDIPVYHPDVRVWEIFDHNGVGLALFYGDFFARDSKSGGAWMGNFVEQSTLNKTHPVIYNV
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Template Sequence  VTSTMLQQGWNAT. . . . . . . . . HMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAW. . . DFYNRKDFRIK
Template Known Secondary structure  TTS


.........TT




S
B
S

SS





S
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SSSS
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   279280.........290. ........300.........310.........320.........330..... ....340......
 
   447..450.........460.........470.........480.........490.........500.........510.........520......
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Query Sequence  CNYQKPAAGEPALLLWDDVITLFHEFGHTLHGLFARQRYATLSGTNTPRDFVEFPSQINEHWATHPQVFARYARHYQSGA
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Template Sequence  QCTRV. . . . . . . . . TMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANP. GFHEAIGDVLALSVSTPEHLHKIGLLDRVTN
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TTS
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   347..350. ........360.........370.........380..... ....390.........400.........410......
 
   527..530.........540.........550.........560.........570.........580........ .590.........600..
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Query Sequence  AMPDELQQKMRNASLFNKGYEMSELLSAALLDMRWHCLEENEAMQDVDDFELRALVAENMDL. . . . PAIPPRYRSSYFAH
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Template Sequence  DTESDINYLLKMALEKIAFLPFG. . . . . YLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFH
Template Known Secondary structure  STT.....TSS
GGG

SS


TT

SGGGSTT
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   417..420.........430......... 440.........450.........460.........470.........480.........490.
 
   603......610.........620.........630..... ....640.........650.........660..... ....670
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Query Sequence  IFGGGYAAGYYAYLWTQMLADDGYQWFVEQGGL. . . . . . . . . . . TRENGLRFREAILSRGNSEDLERLYRQWRG. KAPKI
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Template Sequence  V. . . PNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRK. VLQAGSSRPWQEVLKDMVGLDALDA
Template Known Secondary structure  T...TTT


T

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GGG


TT
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SS

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   492 .......500.........510.........520.........530.........540.. .......550.........560.......
 
   671.....
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Query Sequence  MPMLQH
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Template Sequence  QPLLKY
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   568.570...
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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