Job Description P37659 Confidence 92.59% Date Thu Jan 5 11:56:31 GMT 2012 Rank 14 Aligned Residues 272 % Identity 14% Template c2xrgA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor Resolution 3.20 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.			.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.		.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.
Predicted Secondary structure																				.	.																						.
Query SS confidence																				.	.																						.
Query Sequence		L	L	V	I	N	I	C	S	L	S	W	S	D	I	E	A	A	G	.	.	L	M	S	H	P	L	W	S	H	F	D	I	E	F	K	N	F	N	S	A	T	.	S	Y	S	G	P	A	A	I	R	L	L	R	A	S	C	G	Q	T	S	H	T	N	L	Y	Q	P	A	N	N	D	C	Y	L	F	D	N	L	S
Query Conservation																				.	.																						.
Alig confidence																				.	.																						.															.	.											.	.	.	.	.
Template Conservation																																																										.	.											.	.	.	.	.
Template Sequence		L	I	I	F	S	V	D	G	F	R	A	S	Y	M	K	K	G	S	K	V	M	P	N	I	E	K	L	R	S	C	G	T	H	A	P	Y	M	R	P	V	Y	P	T	K	T	F	P	N	L	Y	T	L	A	T	G	L	.	.	Y	P	E	S	H	G	I	V	G	N	.	.	.	.	.	S	M	Y	D	P	V	F
Template Known Secondary structure									T			G	G	G	G	G	S		T	T	T	S										S				S						S	S		S												S	.	.						S				S	.	.	.	.	.	S				T	T	T
Template Predicted Secondary structure																																																										.	.											.	.	.	.	.
Template SS confidence
		165	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220			.	.	.	.	.	.	.	.	.	230						.	.	.	.	.	.	.
		314	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.				330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.		.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																		.	.	.																																		.
Query SS confidence																		.	.	.																																		.
Query Sequence		K	L	G	F	T	Q	H	L	M	M	G	H	N	G	Q	F	.	.	.	G	G	F	L	K	E	V	R	E	N	G	G	M	Q	S	E	L	M	D	Q	T	N	L	P	V	I	L	L	G	F	D	G	S	.	P	V	Y	D	D	T	A	V	L	N	R	W	L	D	V	T	E	K	D	K	N	S	R	S	A	T	F
Query Conservation																		.	.	.																																		.
Alig confidence																		.	.	.																			.	.	.	.	.	.	.	.	.	.	.					.
Template Conservation																																							.	.	.	.	.	.	.	.	.	.	.
Template Sequence		D	A	S	F	H	L	R	G	R	E	K	F	N	H	R	W	W	G	G	Q	P	L	W	I	T	A	T	K	Q	G	V	R	A	G	T	F	F	.	.	.	.	.	.	.	.	.	.	.	W	S	V	S	I	P	H	E	R	R	I	L	T	I	L	Q	W	L	S	L	P	D	N	E	R	P	S	V	Y	A	F	Y
Template Known Secondary structure		T					S	S	S	S	G	G	G		T	T	S			S									T	T	T			B					.	.	.	.	.	.	.	.	.	.	.			T	T	S													T	T	S		T	T	T			S
Template Predicted Secondary structure																																							.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		238	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.												.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.
		390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.			.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.
Predicted Secondary structure																																													.	.
Query SS confidence																																													.	.
Query Sequence		Y	N	T	L	P	L	H	D	G	N	H	Y	P	G	V	S	K	T	A	D	Y	K	A	R	A	Q	K	F	F	D	E	L	D	A	F	F	T	E	L	E	K	S	G	.	.	R	K	V	M	V	V	V	V	P	E	H	G	G	A	L	K	G	D	R	M	Q	V	S	G	L	R	D	I	P	S	P	S	I	T	D
Query Conservation																																													.	.
Alig confidence						.	.														.																								.	.													.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation						.	.														.																																						.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		S	E	Q	P	.	.	D	F	S	G	H	K	Y	G	P	F	G	P	E	.	M	T	N	P	L	R	E	I	D	K	T	V	G	Q	L	M	D	G	L	K	Q	L	R	L	H	R	C	V	N	V	I	F	V	G	D	H	G	.	.	.	.	.	.	.	.	.	.	.	.	M	E	D	V	T	C	D	R	T	E	F
Template Known Secondary structure						.	.									T	T		G	G	.	G																					T	T		T	T	T								S			.	.	.	.	.	.	.	.	.	.	.	.						S	S	S
Template Predicted Secondary structure						.	.														.																																						.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		307	.	.	310			.	.	.	.	.	.	.	.	.	320	.	.	.		.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360													.	.	.	.	.	.	.	.	.	370	.
		468	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.			.	.	.	.	.	540	.	.	.	.	.
Predicted Secondary structure																																																																					.	.
Query SS confidence																																																																					.	.
Query Sequence		V	P	V	G	V	K	F	F	G	M	K	A	P	H	Q	G	A	P	I	V	I	E	Q	P	S	S	F	L	A	I	S	D	L	V	V	R	V	L	D	G	K	I	F	T	E	D	N	V	D	W	K	K	L	T	S	G	L	P	Q	T	A	P	V	S	E	N	S	.	.	N	A	V	V	I	Q	Y	Q	D	K	P
Query Conservation																																																																					.	.
Alig confidence																													.	.	.																							.	.	.													.	.
Template Conservation																													.	.	.																							.	.	.
Template Sequence		L	S	N	Y	L	T	N	V	D	D	I	T	L	V	P	G	T	L	G	R	I	R	A	K	Y	D	P	.	.	.	K	T	I	I	A	A	L	T	C	K	K	P	D	Q	H	F	K	P	Y	M	K	Q	.	.	.	H	L	P	K	R	L	H	Y	A	N	N	R	R	I	E	D	I	H	L	L	V	D	R	R	W
Template Known Secondary structure		G	G	G	T		S			T	T						B	S											.	.	.						T	T	S	S		S	T	T								G	G	.	.	.	G	S		G	G	G				S	S	T	T	S		S							T	T
Template Predicted Secondary structure																													.	.	.																							.	.	.
Template SS confidence
		372	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.				.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420				.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.
		546	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		H	V
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		452	.

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions