|   |
45 | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | P | Y | T | W | E | N | L | C | Q | P | L | A | E | V | D | D | V | L | G | R | I | F | S | P | V | S | H | L | N | S | V | K | N | S | P | E | L | R | E | A | Y | E | Q | T | L | P | L | L | S | E | Y | S | T | W | V | G | Q | H | E | G | L | Y | K | A | Y | R | D | L | R | D | G | D | H | Y | A | T | L | N | T |
Query Conservation |   |
  |   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |
|   |   |   |   |   |   |
| . |   |   |
|   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   | . | . | . |   |   |   |   |   |
|   |
|
Template Sequence |   |
Q | N | E | T | I | K | Q | I | L | A | K | Y | R | R | I | . |
W | A | I | G | H | A | Q | S | V | L | G | W | D | L | E | V | N | M | P | K | E | G | I | L | E | R | S | V | A | Q | G | E | L | S | V | L | S | H | E | L | L | L | H | P | E | F | V | N | L | V | E | K | A | . |
. |
. |
K | G | L | E | N | L | N | E |
Template Known Secondary structure |   |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  |  | . | . | . |  |  |
| S |
|
|
|  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  | . | . | . |  |
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
6 | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | |
. | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | |
|
|
. | . | . | . | . | . | 80 | . |
  |
  |   |
125 | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | Q | K | K | A | V | D | N | A | L | R | D | F | E | L | S | G | I | G | L | P | K | E | K | Q | Q | R | Y | G | E | I | A | T | R | L | S | E | L | G | N | Q | Y | S | N | N | V | L | D | A | T | M | G | W | T | K | L | V | T | D | E | A | E | L | A | G | M | P | E | S | A | L | A | A | A | K | A | Q | A | E | A |
Query Conservation |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   | . | . | . | . | . |   |   |
|   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
Y | E | R | G | I | V | R | V | L | D | R | S | I | R | I | A | R | . |
A | F | P | P | E | F | I | R | E | V | S | E | T | T | S | L | A | T | K | A | W | E | E | A | K | A | . |
. |
. |
. |
. |
K | D | D | F | S | K | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | T | T |
| G | G | G | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |  |
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | |
. | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 130 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
205 | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | E | L | E | G | Y | L | L | T | L | D | I | P | S | Y | L | P | V | M | T | Y | C | D | N | Q | A | L | R | E | E | M | Y | R | A | Y | S | T | R | A | S | D | Q | G | P | N | A | G | K | W | D | N | S | K | V | M | E | E | I | L | A | L | R | H | E | L | A | Q | L | L | G | F | E | N | Y | A | F | K | S | L | A |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |
|   |   |
|
|   |
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |
|
|   |
|
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | P | W | L | D | K | I | I | S | L | A | K | R | A | A | E | Y | L | G | Y | E | E | E | P | Y | D | A | L | L |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | S |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
132 | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
  |
  |   |
285 | . | . | . | |
|
. | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . |
Predicted Secondary structure |   |
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | K | M | A | . |
. |
E | N | P | Q | Q | V | L | D | F | L | T | D | L | A | K | R | A | R | P | Q | G | E | K | E | L | A | Q | L | R | A | F | A | K | A | E | F | G | V | D | E | L | Q | P | W | D | I | A | Y | Y | S | E | K | Q | K | Q | H | L | Y | S | I | S | D | E | Q | L | R | P | Y | F | P | E | N | K | A |
Query Conservation |   |
  |   |   |   | . | . |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |   |   |
|
Alig confidence |   |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
D | L | Y | E | E | G | L | R | T | R | D | V | E | K | M | F | E | V | L | E | K | K | L | K | P | L | L | D | K | I | L | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | G | K | V | P | R | E | H | P | L | E | K | E | K | Y | E | R | E | W | M |
Template Known Secondary structure |   |
 |  |  | S | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
| S | S |
| S |
|
| G | G | G | T |
| B |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . |
  |
  |   |
363 | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | N | G | L | F | E | V | V | K | R | I | Y | G | I | T | A | K | E | R | K | D | V | D | V | W | H | P | D | V | R | F | F | E | L | Y | D | E | N | N | E | L | R | G | S | F | Y | L | D | L | Y | A | R | E | N | K | R | G | G | A | W | M | D | D | C | V | G | Q | M | R | K | A | D | G | S | L | Q | K | P | V | A |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   | . |
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
E | R | V | N | L | W | I | L | Q | K | . |
F | G | F | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | G | T | R | A | R | L | D | V | S | A | H | P | F | T | T | E | F | G | I | R | D | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | . |  | T |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | B | T | T | T |  |  |  |  |  |
| S | S |
|
|  |  |  |  |  | T | T |  |  | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | . |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
213 | . | . | . | . | . | . | 220 | . | . | |
. | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
  |
  |   |
443 | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | |
|
. | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
510 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |  |
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
Query Sequence |   |
Y | L | T | C | N | F | N | R | P | V | N | G | K | P | A | L | F | T | . |
. |
H | D | E | V | I | T | L | F | H | E | F | G | H | G | L | H | H | M | L | T | R | I | E | T | A | G | V | S | G | I | S | G | V | P | W | D | A | V | E | L | P | S | Q | F | M | E | N | W | C | . |
. |
. |
. |
. |
W | E | P | E | A | L |
Query Conservation |   |
  |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   | . | . |   |   |
|
|   |
|
|   |
|
|
|
|
|
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |
|
|   |   |
|   |   |   |
|   |   |   | . | . | . | . | . |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|   |   |   |   | . | . | . | . | . | . | . | . | . |   |
|
|   |   |   |
|   |
|   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|
|
|
|
|   |   |   |
|   |   |
|   |   |
|   |   |
|   |   |   |
|   |
Template Sequence |   |
R | I | T | T | R | Y | E | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
Y | D | F | R | R | T | I | L | S | T | V | H | E | F | G | H | A | L | Y | E | L | Q | Q | D | E | R | F | M | F | T | P | I | A | G | G | V | S | L | G | I | H | E | S | Q | S | R | F | W | E | N | I | I | G | R | S | K | E | F | V | E | L | I | Y |
Template Known Secondary structure |   |
 |  |  |  |
|
|
| S | . | . | . | . | . | . | . | . | . | B |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
| G | G | G | T | T | S | T | T | S | S |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T | T | S |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
250 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 |
  |
  |   |
516 | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | F | I | S | G | H | Y | E | T | G | E | P | L | P | K | E | L | L | D | K | M | L | A | A | K | N | Y | Q | A | A | L | F | I | L | R | Q | L | E | F | G | L | . |
. |
. |
. |
. |
. |
. |
F | D | F | R | L | H | A | E | F | R | P | D | Q | G | A | K | I | L | E | T | L | A | E | I | K | K | L | V | A | V | V | P |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   | . | . | . | . | . | . | . |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|
|
|   |
|
|   |   |
|
|   |
|
|   |
|   |
|   |   |
|   | . | . |   |
|   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |   |   |
|   |
|
|   |
Template Sequence |   |
P | V | L | K | E | N | L | P | F | M | S | N | Y | T | P | E | D | V | Y | L | Y | F | N | I | V | R | P | D | F | I | R | T | E | A | D | V | V | T | Y | N | F | H | I | L | L | R | F | K | L | E | R | L | M | V | . |
. |
S | E | E | I | K | A | K | D | L | P | E | M | W | N | D | E | M | E | R | L | L | G | I | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |
| G | G | G | G | G |
|
|  |  |  |  |  |  |  |  | T |
|
|
|
|
| S |
| G | G | G |
|
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  | S |
|
|
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
321 | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | |
|
. | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . |
  |
  |   |
589 | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | P | S | W | G | R | F | P | H | A | F | S | H | I | F | A | G | G | Y | A | A | G | Y | Y | S | Y | L | W | A | D | V | L | A | A | D | A | F | S | R | F | E | E | E | G | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
F | N | R | E | T | G | Q | S | F | L | D | N | I | L | S | R | G | G | S | E | E | P | M | D | L | F |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |
|   |
|
|
|   |
|
|   |   | . |
|   |   |
|
|
|   |
|
|   |
|
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |
|   |
|   |   |   |   |
|
|
|
Template Sequence |   |
P | R | K | Y | S | E | G | I | L | Q | D | I | H | W | A | H | . |
G | S | I | G | Y | F | P | T | Y | T | I | G | T | L | L | S | A | Q | L | Y | Y | H | I | K | K | D | I | P | D | F | E | E | K | V | A | K | A | E | F | D | P | I | K | A | W | L | R | E | K | I | H | R | W | G | S | I | Y | P | P | K | E | L | L |
Template Known Secondary structure |   |
| S | S | G | G | G | T | T | T | S |
| S |  |  |  |  | . | T |
|
| S |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | T | T |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |  |  |  | T | G | G | G | T | T | S | S |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
399 | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | |
. | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . |
  |
  |   |
660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | R | F | R | G | R | E | P | Q | L | D | A | M | L | E | H | Y |
Query Conservation |   |
  |   |
|
|
|
|   |   |   |   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|   |   |
|   |   |   |   |   |   |   |
|
|
Template Sequence |   |
K | K | A | I | G | E | D | M | D | A | E | Y | F | V | R | W | V |
Template Known Secondary structure |   |
 |  |  |  | S | S |
|
|
| T |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
478 | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . |
  |