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Job DescriptionP27298
Confidence100.00%DateWed Jan 25 15:20:46 GMT 2012
Rank1Aligned Residues670
% Identity32%Templatec1y791_
PDB info PDB header:hydrolaseChain: 1: PDB Molecule:peptidyl-dipeptidase dcp; PDBTitle: crystal structure of the e.coli dipeptidyl carboxypeptidase2 dcp in complex with a peptidic inhibitor
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2..... ..10.........20.........30.........40.........50.........60.........70.......
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Query Sequence  TNPLLT. . . . PFELPPFSKILPEHVVPAVTKALNDCRENVERVVAQGAPYTWENLCQPLAEVDDVLGRIFSPVSHLNSVK
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Template Conservation   

 
    
    
 
          
              
       
    
  

     
              
Template Sequence  MNPFLVQSTLPYLAPHFDQIANHHYRPAFDEGMQQKRAEIAAIALNPQMPDFNNTILALEQSGELLTRVTSVFFAMTAAH
Template Known Secondary structure 

GGGS


SGGG


TTT

GGGTTSSSS



S
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   3......10.........20.........30.........40.........50.........60.........70.........80..
 
   78.80.........90.........100.........110.........120.........130.........140.........150.......
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Query Sequence  NSPELREAYEQTLPLLSEYSTWVGQHEGLYKAYRDLRDGDHYATLNTAQKKAVDNALRDFELSGIGLPKEKQQRYGEIAT
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Template Conservation                 
      
     

  
           
  
               
  
          
  
Template Sequence  TNDELQRLDEQFSAELAELANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQRFVLAGAKLAQADKAKLKVLNT
Template Known Secondary structure 

S
TTTTS


TTT

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   83......90.........100.........110.........120.........130.........140.........150.........160..
 
   158.160.........170.........180.........190.........200......... 210.........220.........230......
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Query Sequence  RLSELGNQYSNNVLDATMGWTKLVTDEAELAGMPESALAAAKAQAEAKELEG. YLLTLDIPSYLPVMTYCDNQALREEMY
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Template Conservation      
   
                    
 
 
                 
     
        
    
   

 
 
Template Sequence  EAATLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAEAAREKGLDNKWLIPLLNTTQQPALAEMRDRATREKLF
Template Known Secondary structure  T
SS
GGGGTTS
TT
TT



SSSS
GGGGT


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   163......170.........180.........190.........200.........210.........220.........230.........240..
 
   237..240.........250.........260.........270.........280.........290.........300.........310......
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Query Sequence  RAYSTRASDQGPNAGKWDNSKVMEEILALRHELAQLLGFENYAFKSLATKMAENPQQVLDFLTDLAKRARPQGEKELAQL
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Template Conservation   
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Template Sequence  IAGWTRAEKNDAND. . . . TRAIIQRLVEIRAQQATLLGFPHYAAWKIADQMAKTPEAALNFMREIVPAARQRASDELASI
Template Known Secondary structure  TTT
SSSTT
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TT
SSTTSTT
S
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   243......250...... ...260.........270.........280.........290.........300.........310........
 
   317..320.........330.........340.........350.........360... ......370.........380.........390.....
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Query Sequence  RAFAKAEFGVDELQPWDIAYYSEKQKQHLYSISDEQLRPYFPENKAV. NGLFEVVKRIYGITAKERKDVDVWHPDVRFFE
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Template Conservation     
    
   
  

  
                   


    
  

  
   


           
   
    
Template Sequence  QAVIDKQQGGFSAQPWDWAFYAEQVRREKFDLDEAQLKPYFELNTVLNEGVFWTANQLFGIKFVERFDIPVYHPDVRVWE
Template Known Secondary structure  TT

S


S

GGGTGGG
BT

SSS

SSTT
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   319320.........330.........340.........350.........360.........370.........380.........390........
 
   396...400.........410.........420.........430.........440.........450.........460.........470.....
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Query Sequence  LYDENNELRGSFYLDLYARENKRGGAWMDDCVGQMRKADGSLQKPVAYLTCNFNRPVNGKPALFTHDEVITLFHEFGHGL
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Template Sequence  IFDHNGVGLALFYGDFFARDSKSGGAWMGNFVEQST. . . LNKTHPVIYNVCNYQKPAAGEPALLLWDDVITLFHEFGHTL
Template Known Secondary structure 
TTS


TTS
SS


BT...TTTB





TTS

B

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   399400.........410.........420.........430.... .....440.........450.........460.........470.....
 
   476...480.........490.........500.........510.........520.........530.........540.........550.....
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Query Sequence  HHMLTRIETAGVSGISGVPWDAVELPSQFMENWCWEPEALAFISGHYETGEPLPKELLDKMLAAKNYQAALFILRQLEFG
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Template Conservation 
  

       

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Template Sequence  HGLFARQRYATLSG. TNTPRDFVEFPSQINEHWATHPQVFARYARHYQSGAAMPDELQQKMRNASLFNKGYEMSELLSAA
Template Known Secondary structure  T


SSGGGST.T
S
GGGS
B
TTT

B

TTTTT
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   476...480......... 490.........500.........510.........520.........530.........540.........550....
 
   556...560.........570...... ...580.........590.........600.........610.........620.........630....
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Query Sequence  LFDFRLHAEFRPDQGAKILET. LAEIKKLVAVVPSPSWGRFPHAFSHIFAGGYAAGYYSYLWADVLAADAFSRFEEEGIF
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Template Conservation   

   
                                     
 
     
 
 

 
     

  
       
  
Template Sequence  LLDMRWHCLEENEAMQDVDDFELRALVAENMDLPAIPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADDGYQWFVEQGGL
Template Known Secondary structure  TT

GGG



TT

BTTB

SS
GGG
TSS
TTTTTTSS
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   555....560.........570.........580.........590.........600.........610.........620.........630....
 
   635....640.........650.........660.........670.........
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Query Sequence  NRETGQSFLDNILSRGGSEEPMDLFKRFRGREPQLDAMLEHYGIK
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Template Conservation      
       
  


  
 


  
 

 
   
 
   
  
Template Sequence  TRENGLRFREAILSRGNSEDLERLYRQWRGKAPKIMPMLQHRGLN
Template Known Secondary structure 
TTTTTTSS
SS


STT

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   635....640.........650.........660.........670.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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