|   |
47 | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | |
|
|
. | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | T | W | E | N | L | C | Q | P | L | A | E | V | D | D | V | L | G | R | I | F | S | P | V | S | H | L | N | . |
. |
. |
S | V | K | N | S | P | E | L | R | E | A | Y | E | Q | T | L | P | L | L | S | E | Y | S | T | W | V | G | Q | H | E | G | L | Y | K | A | Y | R | D | L | R | D | G | D | H | Y | A | T | L | N |
Query Conservation |   |
  |
|   |   |   |   |
|   |   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|
|   |   |
|   |
|
|   |   |   |   |   |   |
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
M | T | P | E | A | A | Y | Q | N | L | L | E | F | Q | R | E | T | A | Y | L | A | S | L | G | A | L | A | A | W | D | Q | R | T | M | I | P | K | K | G | H | E | H | R | A | R | Q | M | A | A | L | A | R | L | L | H | Q | R | M | T | D | P | R | I | G | E | W | L | E | K | V | E | G | S | P | L | V | Q | D | P | L |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  |  | T | T | S | G | G | G | S | S | T | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
  |
  |   |
124 | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | A | Q | K | K | A | V | D | N | A | L | R | D | F | E | L | S | G | I | G | L | P | K | E | K | Q | Q | R | Y | G | E | I | A | T | R | L | S | E | L | G | N | Q | Y | S | N | N | V | L | D | A | T | M | G | W | T | K | L | V | T | D | E | A | E | L | A | G | M | P | E | S | A | L | A | A | A | K | A | Q | A | E |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
S | D | A | A | V | N | V | R | E | W | R | Q | A | Y | E | R | A | R | A | . |
I | P | E | R | L | A | V | E | L | A | Q | A | E | S | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | |
100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
204 | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | |
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
A | K | E | L | E | G | Y | L | L | T | L | D | I | P | S | Y | L | P | V | M | T | Y | C | D | N | Q | A | L | R | E | E | M | Y | R | A | Y | S | T | R | A | S | D | Q | G | P | N | A | G | K | W | D | N | S | K | V | M | E | E | I | L | A | L | R | H | E | L | A | Q | L | L | G | F | E | . |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|
|   | . | . | . | . | . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |
|   |
|   |
|   |   |
|
|   |
|   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | E | S | F | W | E | E | A | R | P | R | D | D | W | R | G | F | L | P | Y | L | K | R | V | Y | A | L | T | K | E | K | A | E | V | L | F | A | L | P | P | A | P | G | D | P |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  | T | T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|
| S | T | T | S |
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
115 | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
277 | . | . | 280 | . | . | . | . | . | . | . | . | . | |
290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . |
Predicted Secondary structure |   |
. | . | . |
|  |  |  |  |  |  |  |
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
N | Y | A | F | K | S | L | A | T | K | M | A | E | . |
N | P | Q | Q | V | L | D | F | L | T | D | L | A | K | R | A | R | P | Q | G | E | K | E | L | A | Q | L | R | A | F | A | K | A | E | F | G | V | D | E | L | Q | P | W | D | I | A | Y | Y | S | E | K | Q | K | Q | H | L | Y | S | I | S | D | E | Q |
Query Conservation |   |
. | . | . |
|   |   |   |   |   |
|   |   |   |   |   |   | . |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|   |
|
|
|   |
|
|   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | Y | G | E | L | Y | D | A | L | L | D | G | Y | E | P | G | M | R | A | R | E | L | L | P | L | F | A | E | L | K | E | G | L | K | G | L | L | D | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | L | G | S | G | K | R | P | D | T | S | I |
Template Known Secondary structure |   |
|
|
| S |  |  |  |  |  |  |  |  |  | S | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  | T | T |
|
|
|
|
| G | G | G |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 200 | . | . | . | . | . | . | . | . | . | 210 |
  |
  |   |
353 | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | |
. | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | P | Y | F | P | E | N | K | A | V | N | G | L | F | E | V | V | K | R | I | Y | G | I | T | A | K | E | R | K | D | V | D | V | W | H | P | D | V | R | F | F | E | L | Y | D | E | N | N | E | L | R | G | S | F | Y | L | D | L | . |
Y | A | R | E | N | K | R | G | G | A | W | M | D | D | C | V | G | Q | M | R |
Query Conservation |   |
  |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |
|
|
|   | . |   |   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |
|
|
|
|   |
|   |
|
|
|   |   |   |   |   |   |   |
|
|
Template Sequence |   |
L | H | R | P | Y | P | V | E | A | Q | R | R | F | A | L | E | L | L | S | A | C | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | D | L | E | A | G | R | L | D | P | T | A | H | P | F | E | I | A | I | G | P | G | D | V |
Template Known Secondary structure |   |
G | G | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
| G | G | G |  |  |  |  |  |
| S | S |
|
|  |  |  |  |  | T | T |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
211 | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . |
  |
  |   |
432 | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | |
|
. | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | A | D | G | S | L | Q | K | P | V | A | Y | L | T | C | N | F | N | R | P | V | N | G | K | P | A | L | F | T | . |
. |
H | D | E | V | I | T | L | F | H | E | F | G | H | G | L | H | H | M | L | T | R | I | E | T | A | G | V | S | G | I | S | G | V | P | W | D | A | V | E | L | P | S | Q | F | M | E | N | W | C |
Query Conservation |   |
  |   |   |   |   |   |
|   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   | . | . |   |   |
|
|   |
|
|   |
|
|
|
|
|
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |
|
|   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|   |
|   |   | . | . | . | . | . | . | . | . | . |   |
|
|   |   |   |
|   |
|   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|
|
|
|
|   |   |   |
|
|   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | I | T | T | R | Y | Y | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
D | F | F | N | A | G | I | F | G | T | L | H | E | M | G | H | A | L | Y | E | Q | G | L | P | K | E | H | W | G | T | P | R | G | D | A | V | S | L | G | V | H | E | S | Q | S | R | T | W | E | N | L | V |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
| T | . | . | . | . | . | . | . | . | . | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| G | G | G | T | T | S | G | G | G | S |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
257 | . | . | 260 | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . |
  |
  |   |
|
510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | |
|
|
|
|
|
. | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. |  |
|  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
W | E | P | E | A | L | A | F | I | S | G | H | Y | E | . |
. |
. |
. |
. |
T | G | E | P | L | P | K | E | L | L | D | K | M | L | A | A | K | N | Y | Q | A | . |
. |
. |
. |
. |
. |
A | L | F | I | L | R | Q | L | E | F | G | L | F | D | F | R | L | H | A | E | F | R | P | D | Q | G | A | K | I | L | E | T | L |
Query Conservation |   |
. |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |
|   |
|   |   |   |
|
|
|   |
|
|
|
|   |
|
|   |
|
|
|   |
|
|   |
|   |
|
|   |
|   | . | . |   |
|   |
|   |   |   |
|
|   |   |   |
|
Template Sequence |   |
G | R | S | L | G | F | W | E | R | F | F | P | R | A | R | E | V | F | A | S | L | G | D | V | S | L | E | D | F | H | F | A | V | N | A | V | E | P | S | L | I | R | V | E | A | D | E | V | T | Y | N | L | H | I | L | V | R | L | E | L | E | L | A | L | F | . |
. |
R | G | E | L | S | P | E | D | L | P | E | A | W |
Template Known Secondary structure |   |
T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G | T | T |
|
|  |  |  |  |  |  |  | T | T |
|
|
|
|
| S |
| T | T | T |
|
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | T | T | S |
|
| G | G | G |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
317 | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | |
|
. | . | . | . | . | . | . | . | 390 | . | . | . | . |
  |
  |   |
578 | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | 640 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | E | I | K | K | L | V | A | V | V | P | S | P | S | W | G | R | F | P | H | A | F | S | H | I | F | A | G | G | Y | A | A | G | Y | Y | S | Y | L | W | A | D | V | L | A | A | D | A | F | S | R | F | E | E | E | G | I | F | N | R | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
T | G | Q | S | F | L | D | N | I | L | S |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|
|
|
|   |
|   |   |
|   |   |
|   |
|
|
|   |
| . |
|
|   |
|   |   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
Template Sequence |   |
A | E | K | Y | R | D | H | L | G | V | A | P | K | D | Y | K | D | G | V | M | Q | D | V | H | . |
W | A | G | G | L | F | G | Y | F | P | T | Y | T | L | G | N | L | Y | A | A | Q | F | F | Q | K | A | E | A | E | L | G | P | L | E | P | R | F | A | R | G | E | F | Q | P | F | L | D | W | T | R | A | R | I | H | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | S |
|
|
| S | S | S | T | T | T | G | G | G |
| S | G | . | G | G | G | T |
|
| S |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  | T | G | G |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
395 | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | |
. | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . |
  |
  |   |
649 | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | G | G | S | E | E | P | M | D | L | F | K | R | F | R | G | R | E | P | Q | L | D | A | M | L | E | H | Y |
Query Conservation |   |
  |
|
|
|   |   |
|   |
|   |
|   |   |
|
|
|
|   |   |   |   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |   |   |   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |
|
|
Template Sequence |   |
E | G | S | R | F | R | P | R | V | L | V | E | R | V | T | G | E | A | P | S | A | R | P | F | L | A | Y | L |
Template Known Secondary structure |   |
G | T | T | S | S |
|  |  |  |  |  |  |  |  |  | S | S |
|
|
| S |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
474 | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . |
  |