|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
K | L | T | I | G | L | I | G | N | P | N | S | G | K | T | T | L | F | N | Q | L | T | G | S | R | Q | R | V | G | N | W | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |
|   |
|
|
|
|
|   |
|
|   |
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |
|
|
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|
|
|
|
|
|
|   |   |
|
|
|
|
|
|   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|
|
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
E | V | K | L | L | L | L | G | A | G | E | S | G | K | S | T | I | V | K | Q | M | K | I | I | H | E | A | G | Y | S | E | E | E | C | K | Q | Y | K | A | V | V | Y | S | N | T | I | Q | S | I | I | A | I | I | R | A | M | G | R | L | K | I | D | F | G | D | S | A | R | A | D | D | A | R | Q | L | F | V | L | A | E |
Template Known Secondary structure |   |
|  |  |  |  |  |  |
| S | T | T | S | S | S |  |  |  |  |  |  |  |  |  | T | T | S |
|
|
|
| T | T | G | G | G | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| S | S | G | G | G |  |  |  |  |  |  |  | T | T | T |
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
33 | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
35 | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | V | T | V | E | R | K | E | G | Q | F | S | T | T | D | H | Q | V | T | L | V | D | L | P |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |
|
|   |
|   |   |
|
|   |   |   |   |
|   |   |   |   |   |
|   |
|
|   |   |
|
|
|   |   |
|   |
|
|   |   |   |   |
|   |
|
|   |   |
|
|
|   |   |
|   |   |
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
Template Sequence |   |
L | A | G | V | I | K | R | L | W | K | D | S | G | V | Q | A | C | F | N | R | S | R | E | Y | Q | L | N | D | S | A | A | Y | Y | L | N | D | L | D | R | I | A | Q | P | N | Y | I | P | T | Q | Q | D | V | L | R | T | R | V | K | T | T | G | I | V | E | T | H | F | T | F | K | D | L | H | F | K | M | F | D | V | G |
Template Known Secondary structure |   |
T | T | T | T | T |  |  |  |  | T | S | S |  |  |  |  |  | T | T |
| G | G | G | S |
|
|
| T | T |  |  |  |  |  | T | T |
| T | T | T |
| S | S | S |
|
|
|
|  |  |  |  |  | S |
|
|
|
|
|
| S |
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
123 | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . |
  |
  |   |
59 | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 100 | . | . | . | . | . | . | . | . | . | 110 | |
|
|
|
. | . | . | . | . | . | . | . | . | 120 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | T | Y | S | L | T | T | I | S | S | Q | T | S | L | D | E | Q | I | A | C | H | Y | I | L | S | G | D | A | D | L | L | I | N | V | V | D | A | S | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | E | R | N | L | Y | L | T | L | Q | L | L | E | . |
. |
. |
. |
L | G | I | P | C | I | V | A | L | N | M |
Query Conservation |   |
|
|
|
|
|   |   |   |   |   |   |   |
|   |
|
|   |
|
|
|   |   |
|   |   |   |   |   |
|
|
|
|   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|   |
|   |
|   |   |
|
|   |
| . | . | . | . |
|
|   |
|
|
|
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |
|   |
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |
|
|
|
|
|   |
|
|
|   |
|
|   |   |   |
|   |   |   |   |
|
|
|   |
|
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|
Template Sequence |   |
G | Q | R | S | E | R | K | K | W | I | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
C | F | E | G | V | T | A | I | I | F | C | V | A | L | S | D | Y | D | L | V | L | A | E | D | E | E | M | N | R | M | H | E | S | M | K | L | F | D | S | I | C | N | N | K | W | F | T | D | T | S | I | I | L | F | L | N | K |
Template Known Secondary structure |   |
| S | G | G | G | G | G | G | G | G | G | . | . | . | . | . | . | . | . | . | . | . | . | G |
| S | S |
|
|  |  |  |  |  |  |  | G | G | G | T | T |
| B |
| S | S | S | T | T | S | B |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| S | T | T | S | S | S |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
203 | . | . | . | . | . | . | 210 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 |
  |
  |   |
122 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | D | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | E | K | Q | N | I | R | I | E | I | D | A | L | S | A | R | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | C | P | V | I | P | L | V | S | T | R | G | R | G | I | E | A | L | K | L | A | I | D | R | Y |
Query Conservation |   |
  |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |
|   |   |
|
|   |   |   |
|
|   |   |
| . | . | . | . | . | . | . | . | . | . |
|   |
|
|
|   |
|
|
|   |   |
|   |
|
|   |
|
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|   |   |
|
|   |   |   |   |
|   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |
|   |
|   |
Template Sequence |   |
K | D | L | F | E | E | K | I | K | K | S | P | L | T | I | C | Y | P | E | Y | A | G | S | N | T | Y | E | E | A | A | A | Y | I | Q | C | Q | F | E | D | L | N | K | R | K | D | T | K | E | I | Y | T | H | F | T | C | A | T | D | T | K | N | V | Q | F | V | F | D | A | V | T | D | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T | T | S |
| G | G | G | T |
| T | T |
|
| S |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| S |
| T | T | T |
|
|  |  |  |  |  |  |
| T | T | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
271 | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . |
  |