Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP27243
DateThu Jan 5 11:43:23 GMT 2012
Unique Job ID7d4d6de964902b7a

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2d07A_
Top template information
PDB header:hydrolase
Chain: A: PDB Molecule:g/t mismatch-specific thymine dna glycosylase;
PDBTitle: crystal structure of sumo-3-modified thymine-dna glycosylase
Confidence and coverage
Confidence: 9.3% Coverage: 8%
33 residues ( 8% of your sequence) have been modelled with 9.3% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
Please note: You must be registered and logged in to use Phyrealarm.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLTSFKLHSLKPYTLKSSMILEIITYILCFFSMIIAFVDNTFSIKIYNITAIVCLLSLIL
Secondary structure 








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   .........70.........80.........90.........100.........110.........120
Sequence  RGRQENYNIKNLILPLSIFLIGLLDLIWYSAFKVDNSPFRATYHSYLNTAKIFIFGSFIV
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   .........130.........140.........150.........160.........170.........180
Sequence  FLTLTSQLKSKKESVLYTLYSLSFLIAGYAMYINSIHENDRISFGVGTATGAAYSTMLIG
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   .........190.........200.........210.........220.........230.........240
Sequence  IVSGVAILYTKKNHPFLFLLNSCAVLYVLALTQTRATLLLFPIICVAALIAYYNKSPKKF
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   .........250.........260.........270.........280.........290.........300
Sequence  TSSIVLLIAILASIVIIFNKPIQNRYNEALNDLNSYTNANSVTSLGARLAMYEIGLNIFI
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   .........310.........320.........330.........340.........350.........360
Sequence  KSPFSFRSAESRAESMNLLVAEHNRLRGALEFSNVHLHNEIIEAGSLKGLMGIFSTLFLY
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   .........370.........380.........390.........400.........410.........
Sequence  FSLFYIAYKKRALGLLILTLGIVGIGLSDVIIWARSIPIIIISAIVLLLVINNRNNTIN
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2d07 chain A

3D model

Region: 304 - 350
Aligned: 33
Modelled: 33
Confidence: 9.3%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:g/t mismatch-specific thymine dna glycosylase;
PDBTitle: crystal structure of sumo-3-modified thymine-dna glycosylase

Phyre2

PDB 1mug chain A

3D model

Region: 304 - 350
Aligned: 33
Modelled: 33
Confidence: 8.9%
Identity: 12%
Fold: Uracil-DNA glycosylase-like
Superfamily: Uracil-DNA glycosylase-like
Family: Mug-like

Phyre2

PDB 1a92 chain B

3D model

Region: 301 - 306
Aligned: 6
Modelled: 6
Confidence: 8.4%
Identity: 17%
PDB header:leucine zipper
Chain: B: PDB Molecule:delta antigen;
PDBTitle: oligomerization domain of hepatitis delta antigen

Phyre2

PDB 2rba chain B

3D model

Region: 304 - 350
Aligned: 33
Modelled: 33
Confidence: 7.6%
Identity: 12%
PDB header:hydrolase/dna
Chain: B: PDB Molecule:g/t mismatch-specific thymine dna glycosylase;
PDBTitle: structure of human thymine dna glycosylase bound to abasic and2 undamaged dna

Phyre2

PDB 1wra chain A domain 1

3D model

Region: 306 - 350
Aligned: 45
Modelled: 45
Confidence: 6.8%
Identity: 7%
Fold: Metallo-hydrolase/oxidoreductase
Superfamily: Metallo-hydrolase/oxidoreductase
Family: Pce catalytic domain-like

Phyre2

PDB 2knc chain A

3D model

Region: 344 - 373
Aligned: 30
Modelled: 30
Confidence: 6.4%
Identity: 17%
PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-iib;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex

Phyre2
1

c2d07A_
2

d1muga_
3

c1a92B_
4

c2rbaB_
5

d1wraa1
6

c2kncA_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2d07A_



9.3 15 PDB header:hydrolase
Chain: A: PDB Molecule:g/t mismatch-specific thymine dna glycosylase;
PDBTitle: crystal structure of sumo-3-modified thymine-dna glycosylase
2d1muga_



8.9 12 Fold:Uracil-DNA glycosylase-like
Superfamily:Uracil-DNA glycosylase-like
Family:Mug-like
3c1a92B_



8.4 17 PDB header:leucine zipper
Chain: B: PDB Molecule:delta antigen;
PDBTitle: oligomerization domain of hepatitis delta antigen
4c2rbaB_



7.6 12 PDB header:hydrolase/dna
Chain: B: PDB Molecule:g/t mismatch-specific thymine dna glycosylase;
PDBTitle: structure of human thymine dna glycosylase bound to abasic and2 undamaged dna
5d1wraa1



6.8 7 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Pce catalytic domain-like
6c2kncA_



6.4 17 PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-iib;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0