|   |
33 | . | . | . | . | . | . | 40 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 50 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 60 | . | . | |
|
. | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  | . | . | . | . | . |  |  |  |  |
|
|  |  |  | . | . | . | . | . | . | . |  |
|
|
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | P | L | A | K | R | Y | A | E | E | G | A | D | E | . |
. |
. |
. |
. |
L | V | F | Y | D | I | T | A | S | . |
. |
. |
. |
. |
. |
. |
S | D | G | R | V | V | D | . |
. |
K | S | W | V | S | R | V | A | E | V | I | D | I | P | F | C | V | A | G | G | I | K | S | L | E | D | A | A | K | I | L | S | F | G | A | D |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |
|
|   |   | . | . | . | . | . |
|   |
|   |
|
|
|   |   | . | . | . | . | . | . | . |   |   |
|   |   |   |   | . | . |   |   |   |
|   |   |
|   |   |   |   |   |   |
|
|   |   |   |
|
|
|   |
|   |
|
|
|   |   |   |
|   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
Template Conservation |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|
|   |
|
|
|   |   |   |   |   |
|   |
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |
| . | . |
|
|   |
|   |   |   |   |   |   |
|   |   |   | . |
|
|
Template Sequence |   |
L | K | V | G | E | E | I | K | R | L | S | E | K | F | K | E | V | E | F | V | F | K | S | S | F | D | K | A | N | R | S | S | I | H | S | F | R | G | H | G | L | E | Y | G | V | K | A | L | R | K | V | K | E | E | F | G | L | K | I | T | T | . |
. |
D | I | H | E | S | W | Q | A | E | P | V | A | E | V | . |
A | D |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |  |  |  |  |  |  |
| B | S |
|
| T | T |
| S | S | T | T | S |
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  | . | . |  |
| S | S | G | G | G |  |  |  |  |  | T | T | . |
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  | . | . |  |
|
|
|  |  |  |  |  |  |  |  |  |  | . |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1020 | . | . | . | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080 | |
|
. | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | |
. | . |
  |
  |   |
99 | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | I | S | I | N | S | P | A | L | A | D | P | T | L | I | T | R | L | A | D | R | F | G | V | Q | C | I | V | V | G | I | D | T | W | Y | D | A | E | T | G | K | Y | H | V | N | Q | Y | T | G | D | E | S | R | T | R | V | T | Q | W | E | T | L | D | W | V | Q | E | V | Q | K | R | G | A | G | E | I | V | L | N | M |
Query Conservation |   |
  |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|
|   |   |   |   |
|   |   |
|
|   |   |   |
|   |   | . | . |
|
|
|
|   |
|
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|   |   |   |
|
|   |   |
|   |
|   |   |
Template Sequence |   |
I | I | Q | I | P | A | F | L | C | R | Q | T | D | L | L | L | A | A | A | K | T | . |
. |
G | R | A | V | N | V | K | K | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | F | L | A | P | W | D | T | K | N | V | V | E | K | L | K | F | G | G | A | K | E | I | Y | L | T | E |
Template Known Secondary structure |   |
 |  |  |  |
| G | G | G | T | T |
|  |  |  |  |  |  |  |  | T | T | . | . | T | S |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T |
|
| G | G | G | G |  |  |  |  |  |  |  |  |  | T | T |
| S | S |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1097 | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | |
|
. | . | 1120 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140 | . | . | . | . | . | . | . | . | . | 1150 | . | . | . |
  |
  |   |
179 | 180 | . | . | . | . | . | . | . | |
|
. | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | |
|
|
|
|
|
. | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
Query Sequence |   |
M | N | Q | D | G | V | R | N | G | . |
. |
Y | D | L | E | Q | L | K | K | V | R | E | V | C | H | V | P | L | I | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | G | G | A | G | T | M | E | H | F | L | E | A | F | R | D | A | D | V | D | G | A | L | A | A | S | . |
. |
. |
. |
. |
. |
V | F |
Query Conservation |   |
|   |   |   |
|   |   |   |
| . | . |   |
|   |
|
|
|   |   |
|   |   |   |   |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|
|   |
|   |   |
|   |   |   |   |
|   |   |   |
|   |
|   |
|
|
|
|   | . | . | . | . | . | . |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
Template Conservation |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   | . | . |
|
|
|   |
|   |
|
|   |   |   |   |
|   |
|   |
|
|
|
|   |
|   |   |   |   |
|   |   |
|   |   |
|
|
|
|   |
|
|   |
|   |
|
|
|   |
|   |   |
|
|   |
|   |
Template Sequence |   |
R | G | T | T | F | G | Y | N | N | L | V | V | D | F | R | S | L | P | I | M | K | Q | W | A | . |
. |
K | V | I | Y | D | A | T | H | S | V | Q | L | P | G | G | L | G | D | K | S | G | G | M | R | E | F | I | F | P | L | I | R | A | A | V | A | V | G | C | D | G | V | F | M | E | T | H | P | E | P | E | K | A | L |
Template Known Secondary structure |   |
|
|  |  |
| S | T | T |
|  |  |
|
| T | T |  |  |  |  |  | T | T | T | S | . | . |  |  |  |  |  | T | T | G | G | G |  |  | T | T |
| S | S | S | S |
|  |  |
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  | S | S | G | G | G |
| S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1154 | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | |
|
. | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200 | . | . | . | . | . | . | . | . | . | 1210 | . | . | . | . | . | . | . | . | . | 1220 | . | . | . | . | . | . | . | . | . | 1230 | . |
  |
  |   |
235 | . | . | |
|
. | . | 240 | . | . | . | . | . | . | . | . | . | 250 |
Predicted Secondary structure |   |
 |
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | K | Q | . |
. |
I | I | N | I | G | E | L | K | A | Y | L | A | T |
Query Conservation |   |
  |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |
|
|   |
|   |
|
|   |   |
|   |   |   |
Template Sequence |   |
S | D | A | S | T | Q | L | P | L | S | Q | L | E | G | I | I | E | A |
Template Known Secondary structure |   |
S |
| T | T | T |
|  |  | G | G | G |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1232 | . | . | . | . | . | . | . | 1240 | . | . | . | . | . | . | . | . | . |
  |