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Job DescriptionP60664
Confidence98.95%DateThu Jan 5 12:07:01 GMT 2012
Rank91Aligned Residues154
% Identity16%Templatec2fptA_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial; PDBTitle: dual binding mode of a novel series of dhodh inhibitors
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   85....90.........100........ .110.........120.........130.........140.........150......
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Query Sequence  SLEDAAKILSFGADKISINSPALA. . . . . . . . DPTLITRLADRFGVQCIVVGIDTWYDAETGKYHVNQYTGDESRTRVTQ
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Template Sequence  DYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTK. . . . . VLQERDGLRRVHRPAVLVKIA. . . . . . PDLTS
Template Known Secondary structure  GGG
S


TTSTTSGGGGS.....TS
GGG


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   194.....200.........210.........220.........230...... ...240.........250....... ..260..
 
   157..160.........170.........180......... 190.........200 .........210......
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Query Sequence  WETLDWVQEVQKRGAGEIVLNMMNQDGVRNGYD. . . . . . . . . . . . . . . . . . LEQLKKVREVC. . HVPLIASGGAGTMEHF
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Template Sequence  QDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDA
Template Known Secondary structure  T




BS


TT


TTTTSSSTTT
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S
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   263......270.........280.........290.........300.........310.........320.........330.........340..
 
   217..220.........230.... .....240.........250
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Query Sequence  LEAFRDADVDGALAASVF. HKQIINIGELKAYLAT
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Template Sequence  LEKI. RAGASLVQLYTALTFWGPPVVGKVKRELEA
Template Known Secondary structure  .T
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T
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   343... ...350.........360.........370......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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