 |
Job Description | P0A9Q7 | Confidence | 48.66% | Date | Thu Jan 5 11:11:00 GMT 2012 |
Rank | 314 | Aligned Residues | 124 |
% Identity | 16% | Template | c3rg9A_ |
PDB info |
PDB header:oxidoreductase/oxidoreductase inhibitor | Chain: A: PDB Molecule:bifunctional dihydrofolate reductase-thymidylate synthase; |
PDBTitle: trypanosoma brucei dihydrofolate reductase (tbdhfr) in complex with2 wr99210
|
Resolution | 2.00 Å |
|
 |
  |   |
403 | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | |
|
|
460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|  | . | . | . |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | G | I | G | D | L | Y | N | F | K | L | A | P | S | L | T | L | G | C | G | S | W | G | G | N | S | I | S | E | N | V | G | P | K | H | L | I | N | K | K | T | V | A | K | R | A | E | N | M | L | W | H | K | L | P | K | S | . |
. |
. |
I | Y | F | R | R | G | S | L | P | I | A | L | D | E | V | I | T | D | G | H |
Query Conservation |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |   | . | . | . |
|   |
|
|   |
|   |
|   |   |
|   |   |   |
|   |   |   |
|   |
Alig confidence |   |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
| . | . |   |   |
|   |
|
|
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|
|
|   |
|
|   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|   |
|
|
|
|   |   |
|
|
|
|
|   |
Template Sequence |   |
G | G | I | G | . |
. |
D | G | G | T | I | P | W | E | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | E | D | M | Q | Y | F | R | R | V | T | T | N | L | R | G | K | N | V | K | P | S | P | S | K | R | N | A | V | V | M | G | R | K | T | W | D | S | L | P | P | K | F | R | P | L | S | N |
Template Known Secondary structure |   |
|  |  |  | . | . | S | S | S | S |
| S |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | S | S | S |
|
|
| B | T | T | B |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| G | G | G | S | S |
| T | T |
Template Predicted Secondary structure |   |
|  |  |  | . | . |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
39 | 40 | . | . | |
|
. | . | . | . | . | . | . | 50 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . |
  |
  |   |
480 | . | . | . | . | . | . | |
|
|
. | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | |
. | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
| . | . | . |
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | R | A | L | I | V | T | . |
. |
. |
D | R | F | L | F | N | N | G | Y | A | D | Q | I | T | S | V | L | K | A | A | G | V | E | T | E | V | F | F | E | V | E | A | D | P | T | L | S | I | V | R | K | G | A | E | L | . |
A | N | S | F | K | P | D | V | I | I | A | L | G | G | G | S | P | M | D | A | A |
Query Conservation |   |
  |   |   |
|
|
|
| . | . | . |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |
|   |   |   |   |   |   | . |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|   |
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|
|   |   |
|
Template Sequence |   |
R | L | N | V | V | L | S | R | S | A | T | K | E | Q | L | L | A | G | I | P | D | P | I | K | R | A | E | A | A | . |
. |
. |
. |
. |
. |
. |
N | D | V | V | A | V | N | G | G | L | E | D | A | L | R | M | L | V | S | K | E | H | T | S | S | I | E | T | V | F | C | I | G | G | G | T | I | Y | K | Q | A |
Template Known Secondary structure |   |
S |  |  |  |  |  |
| S | S |
|
|  |  |  |  |  | T | T |
| S | S |  |  |  |  |  |  |  | G | . | . | . | . | . | . | . | G | G |  |  |  |  | S | S |
|  |  |  |  |  |  |  | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . |
  |
No model constructed - rank, confidence too low
Phyre is for academic use only
Please cite: Protein structure prediction on
the web: a case study using the Phyre server |
Kelley LA and Sternberg MJE. Nature Protocols
4, 363 - 371 (2009) [pdf] [Import into BibTeX] |
  |
|
|